SPDR® S&P Biotech ETF (XBI)
Every component of XBI and its weight in the fund, as of 2026-10-19.
| Component | Weight | % | Sector |
|---|---|---|---|
| MRNAModerna Inc · United States | 2.51% | Healthcare | |
| TWSTTwist Bioscience Corp · United States | 1.82% | Healthcare | |
| NTRANatera Inc · United States | 1.81% | Healthcare | |
| HALOHalozyme Therapeutics Inc · United States | 1.74% | Healthcare | |
| BIIBBiogen Inc · United States | 1.73% | Healthcare | |
| ABBVAbbVie Inc · United States | 1.73% | Healthcare | |
| AMGNAmgen Inc · United States | 1.72% | Healthcare | |
| UTHRUnited Therapeutics Corporation · United States | 1.66% | Healthcare | |
| IOVAIovance Biotherapeutics Inc · United States | 1.65% | Healthcare | |
| EXELExelixis Inc · United States | 1.63% | Healthcare | |
| TGTXTG Therapeutics Inc · United States | 1.61% | Healthcare | |
| GILDGilead Sciences Inc · United States | 1.59% | Healthcare | |
| VRTXVertex Pharmaceuticals Inc · United States | 1.54% | Healthcare | |
| REGNRegeneron Pharmaceuticals Inc · United States | 1.50% | Healthcare | |
| CRSPCrispr Therapeutics AG · United States | 1.46% | Healthcare | |
| SYRESpyre Therapeutics Inc. · United States | 1.41% | Healthcare | |
| INCYIncyte Corporation · United States | 1.41% | Healthcare | |
| PTGXProtagonist Therapeutics Inc · United States | 1.41% | Healthcare | |
| KRYSKrystal Biotech Inc · United States | 1.41% | Healthcare | |
| ALNYAlnylam Pharmaceuticals Inc · United States | 1.40% | Healthcare | |
| NBIXNeurocrine Biosciences Inc · United States | 1.39% | Healthcare | |
| BMRNBiomarin Pharmaceutical Inc · United States | 1.38% | Healthcare | |
| ALKSAlkermes Plc · United States | 1.35% | Healthcare | |
| PCVXVaxcyte Inc · United States | 1.34% | Healthcare | |
| RVMDRevolution Medicines Inc · United States | 1.33% | Healthcare | |
| ERASErasca Inc · United States | 1.32% | Healthcare | |
| PTCTPTC Therapeutics Inc · United States | 1.32% | Healthcare | |
| GRALGRAIL, LLC · United States | 1.31% | Healthcare | |
| CYTKCytokinetics Inc · United States | 1.29% | Healthcare | |
| MDGLMadrigal Pharmaceuticals Inc · United States | 1.29% | Healthcare | |
| BBIOBridgeBio Pharma Inc · United States | 1.28% | Healthcare | |
| ROIVRoivant Sciences Ltd · United States | 1.26% | Healthcare | |
| ORKAOruka Therapeutics, Inc. · United States | 1.25% | Healthcare | |
| NKNantKwest Inc · United States | 1.23% | Healthcare | |
| IONSIonis Pharmaceuticals Inc · United States | 1.23% | Healthcare | |
| UMRXCogent Biosciences Inc · United States | 1.22% | Healthcare | |
| KYMRKymera Therapeutics Inc · United States | 1.21% | Healthcare | |
| INSMInsmed Inc · United States | 1.19% | Healthcare | |
| TVTXTravere Therapeutics Inc · United States | 1.15% | Healthcare | |
| KODKodiak Sciences Inc · United States | 1.14% | Healthcare | |
| RYTMRhythm Pharmaceuticals Inc · United States | 1.11% | Healthcare | |
| PRAXPraxis Precision Medicines Inc · United States | 1.10% | Healthcare | |
| ARWRArrowhead Pharmaceuticals Inc · United States | 1.10% | Healthcare | |
| DNTHDianthus Therapeutics Inc. · United States | 1.07% | Healthcare | |
| VCYTVeracyte Inc · United States | 1.05% | Healthcare | |
| MIRMMirum Pharmaceuticals Inc · United States | 1.02% | Healthcare | |
| CGONCG Oncology, Inc. Common stock · United States | 1.01% | Healthcare | |
| VKTXViking Therapeutics Inc · United States | 0.99% | Healthcare | |
| ARQTArcutis Biotherapeutics Inc · United States | 0.93% | Healthcare | |
| BCTGBCTG Acquisition Corp · United States | 0.92% | Financial Services | |
| CDNACareDx Inc · United States | 0.86% | Healthcare | |
| RLAYRelay Therapeutics Inc · United States | 0.83% | Healthcare | |
| BEAMBeam Therapeutics Inc · United States | 0.83% | Healthcare | |
| RAREUltragenyx · United States | 0.80% | Healthcare | |
| SRRKScholar Rock Holding Corp · United States | 0.75% | Healthcare | |
| RXRXRecursion Pharmaceuticals Inc · United States | 0.74% | Healthcare | |
| CELCCelcuity LLC · United States | 0.72% | Healthcare | |
| DYNDyne Therapeutics Inc · United States | 0.69% | Healthcare | |
| SLSSellas Life Sciences Group Inc · United States | 0.64% | Healthcare | |
| NVAXNovavax Inc · United States | 0.59% | Healthcare | |
| IMVTImmunovant Inc · United States | 0.59% | Healthcare | |
| AGIOAgios Pharm · United States | 0.59% | Healthcare | |
| DNLIDenali Therapeutics Inc · United States | 0.59% | Healthcare | |
| PURRHyperliquid Strategies Inc Common Stock · United States | 0.58% | Financial Services | |
| NRIXNurix Therapeutics Inc · United States | 0.57% | Healthcare | |
| BCRXBioCryst Pharmaceuticals Inc · United States | 0.57% | Healthcare | |
| SMMTSummit Therapeutics PLC · United States | 0.56% | Healthcare | |
| VERAVera Therapeutics Inc · United States | 0.54% | Healthcare | |
| IDYAIdeaya Biosciences Inc · United States | 0.53% | Healthcare | |
| SRPTSarepta Therapeutics Inc · United States | 0.53% | Healthcare | |
| NTLAIntellia Therapeutics Inc · United States | 0.52% | Healthcare | |
| VRDNViridian Therapeutics Inc · United States | 0.51% | Healthcare | |
| ACADACADIA Pharmaceuticals Inc · United States | 0.51% | Healthcare | |
| ADMAADMA Biologics Inc · United States | 0.49% | Healthcare | |
| CLDXCelldex Therapeutics Inc · United States | 0.49% | Healthcare | |
| RCUSArcus Biosciences Inc · United States | 0.47% | Healthcare | |
| QUREUniqure NV · United States | 0.45% | Healthcare | |
| PVLAPalvella Therapeutics, Inc · United States | 0.45% | Healthcare | |
| ABSIAbsci Corp · United States | 0.45% | Healthcare | |
| VCELVericel Corp Ord · United States | 0.45% | Healthcare | |
| PGENPrecigen Inc · United States | 0.41% | Healthcare | |
| IRONDisc Medicine Inc. · United States | 0.41% | Healthcare | |
| BHVNBiohaven Ltd. · United States | 0.41% | Healthcare | |
| NKTRNektar Therapeutics · United States | 0.39% | Healthcare | |
| SNDXSyndax Pharmaceuticals Inc · United States | 0.35% | Healthcare | |
| IMNMImmunome Inc · United States | 0.34% | Healthcare | |
| STOKStoke Therapeutics Inc · United States | 0.33% | Healthcare | |
| MLYSMineralys Therapeutics, Inc. Common Stock · United States | 0.33% | Healthcare | |
| TRAXFirst Tracks Biotherapeutics · United States | 0.32% | Healthcare | |
| XNCRXencor Inc · United States | 0.31% | Healthcare | |
| ANABAnaptysBio Inc · United States | 0.31% | Healthcare | |
| ORICOric Pharmaceuticals Inc · United States | 0.30% | Healthcare | |
| REPLReplimune Group Inc · United States | 0.30% | Healthcare | |
| INBXInhibrx Biosciences, Inc. · United States | 0.29% | Healthcare | |
| ZBIOZenas BioPharma, Inc. Common Stock · United States | 0.28% | Healthcare | |
| VIRVir Biotechnology Inc · United States | 0.27% | Healthcare | |
| JBIOJade Biosciences, Inc. · United States | 0.24% | Healthcare | |
| KURAKura Oncology Inc · United States | 0.24% | Healthcare | |
| ARDXArdelyx Inc · United States | 0.24% | Healthcare | |
| MNKDMannKind Corp · United States | 0.24% | Healthcare | |
| GERNGeron Corporation · United States | 0.23% | Healthcare | |
| RIGLRigel Pharmaceuticals Inc · United States | 0.23% | Healthcare | |
| VORVor Biopharma Inc · United States | 0.23% | Healthcare | |
| ANNXAnnexon Inc · United States | 0.22% | Healthcare | |
| TYRA_OLDTYRA · United States | 0.22% | Healthcare | |
| GLUEMonte Rosa Therapeutics Inc · United States | 0.21% | Healthcare | |
| VSTMVerastem Inc · United States | 0.20% | Healthcare | |
| CADLCandel Therapeutics Inc · United States | 0.20% | Healthcare | |
| TSHATaysha Gene Therapies Inc · United States | 0.20% | Healthcare | |
| JANXJanux Therapeutics Inc · United States | 0.19% | Healthcare | |
| BCAXBicara Therapeutics Inc. Common Stock · United States | 0.19% | Healthcare | |
| IMMXImmix Biopharma Inc · United States | 0.19% | Healthcare | |
| CRVSCorvus Pharmaceuticals Inc · United States | 0.19% | Healthcare | |
| AVTXAvalo Therapeutics Inc · United States | 0.19% | Healthcare | |
| CGEMCullinan Oncology LLC · United States | 0.18% | Healthcare | |
| COAGHemab Therapeutics Holdings, Inc. Common Stock · United States | 0.16% | Healthcare | |
| FDMT4D Molecular Therapeutics Inc · United States | 0.16% | Healthcare | |
| SVRASavara Inc · United States | 0.16% | Healthcare | |
| AVBPArriVent BioPharma, Inc. Common Stock · United States | 0.16% | Healthcare | |
| OLMAOlema Pharmaceuticals Inc · United States | 0.15% | Healthcare | |
| RGNXRegenxbio Inc · United States | 0.15% | Healthcare | |
| ACHVAchieve Life Sciences Inc · United States | 0.15% | Healthcare | |
| KLRAKailera Therapeutics, Inc. Common Stock · United States | 0.15% | Healthcare | |
| PRMEPrime Medicine, Inc. Common Stock · United States | 0.13% | Healthcare | |
| DMRADamora Therapeutics, Inc. · United States | 0.13% | Healthcare | |
| MYGNMyriad Genetics Inc · United States | 0.13% | Healthcare | |
| IRWDIronwood Pharmaceuticals Inc · United States | 0.13% | Healthcare | |
| SANASana Biotechnology Inc · United States | 0.13% | Healthcare | |
| TKMArbutus Biopharma Corp · Canada | 0.13% | Other | |
| CAPRCapricor Therapeutics Inc · United States | 0.13% | Healthcare | |
| CTMXCytomX Therapeutics Inc · United States | 0.12% | Healthcare | |
| ALLOAllogene Therapeutics Inc · United States | 0.12% | Healthcare | |
| ELYMEliem Therapeutics Inc · United States | 0.12% | Healthcare | |
| EBSEmergent Biosolutions Inc · United States | 0.11% | Healthcare | |
| MNPRMonopar Therapeutics Inc · United States | 0.11% | Healthcare | |
| DSGNDesign Therapeutics Inc · United States | 0.10% | Healthcare | |
| SGMTSagimet Biosciences Inc. Series A Common Stock · United States | 0.10% | Healthcare | |
| EDITEditas Medicine Inc · United States | 0.10% | Healthcare | |
| ALTAltimmune Inc · United States | 0.10% | Healthcare | |
| STTKShattuck Labs Inc · United States | 0.10% | Healthcare | |
| SLDBSolid Biosciences LLC · United States | 0.10% | Healthcare | |
| SPRYARS Pharmaceuticals, Inc · United States | 0.09% | Healthcare | |
| OCGNOcugen Inc · United States | 0.09% | Healthcare | |
| MDXGMiMedx Group Inc · United States | 0.09% | Healthcare | |
| AKTSAktis Oncology, Inc. Common stock · United States | 0.08% | Healthcare | |
| VNDAVanda Pharmaceuticals Inc · United States | 0.08% | Healthcare | |
| PRTAProthena Corporation plc · United States | 0.08% | Healthcare | |
| CABACabaletta Bio Inc · United States | 0.08% | Healthcare | |
| NGNENeurogene Inc · United States | 0.07% | Healthcare | |
| OVIDOvid Therapeutics Inc · United States | 0.07% | Healthcare | |
| ASMBAssembly Biosciences Inc · United States | 0.06% | Healthcare | |
| AURAAura Biosciences Inc · United States | 0.06% | Healthcare | |
| FTHFaeth Therapeutics, Inc. · United States | 0.05% | Healthcare | |
| LXEOLexeo Therapeutics, Inc. Common Stock · United States | 0.05% | Healthcare | |
| CMPX_OLDCompass Therapeutics Inc. · United States | 0.05% | Other | |
| CBIOCrescent Biopharma, Inc. · United States | 0.04% | Healthcare | |
| BBOTBridgeBio Oncology Therapeutics, Inc. · United States | 0.02% | Healthcare |
From the market data provider's fund data, read 2026-10-19. Returns are the fund's own; past returns say nothing certain about future ones. None of this is advice.