Upstream Bio, Inc. (UPB)

Every figure below is the company's own, as filed. Nothing is estimated and nothing is smoothed — a period the filing does not support is left blank rather than drawn. Quarters are the company's own, counted from its financial year ending 12-31. Amounts in USD.

Revenue Quarterly

0 400K 800K 1.2M Q3 '23: 621K Q4 '23: 450K Q1 '24: 640K Q2 '24: 510K Q3 '24: 607K Q4 '24: 613K Q1 '25: 566K Q2 '25: 937K Q3 '25: 683K Q4 '25: 668K Q1 '26: 1M Q2 '26: 773K Q4 '23 Q2 '24 Q4 '24 Q2 '25 Q4 '25 Q2 '26

Gross Profit Quarterly

Nothing in this filer's XBRL supports this figure for the periods asked for, so there is nothing to draw. That is a gap in the filing, not a zero.

Operating Income Quarterly

-60M -40M -20M 0 20M 40M 60M Q3 '23: -9.4M Q4 '23: -14.3M Q1 '24: -15M Q2 '24: -17.5M Q3 '24: -18.9M Q4 '24: -26.3M Q1 '25: -32M Q2 '25: -44.3M Q3 '25: -37.8M Q4 '25: -46.2M Q1 '26: -43.6M Q2 '26: -42.4M Q4 '23 Q2 '24 Q4 '24 Q2 '25 Q4 '25 Q2 '26

Net Income Quarterly

-45M -30M -15M 0 15M 30M 45M Q1 '23: -3.1M Q2 '23: -2.5M Q3 '23: -3.1M Q4 '23: -11.8M Q1 '24: -10.9M Q2 '24: -14.7M Q3 '24: -16M Q4 '24: -21.2M Q1 '25: -27.3M Q2 '25: -40M Q3 '25: -33.7M Q4 '25: -42.5M Q1 '26: -40.6M Q2 '26: -39.7M Q2 '23 Q4 '23 Q2 '24 Q4 '24 Q2 '25 Q4 '25 Q2 '26

Cost of Revenue Quarterly

Nothing in this filer's XBRL supports this figure for the periods asked for, so there is nothing to draw. That is a gap in the filing, not a zero.

Operating Cash Flow Quarterly

-60M -40M -20M 0 20M 40M 60M Q4 '23: -16.1M Q1 '24: -17.6M Q2 '24: -8M Q3 '24: -14M Q4 '24: -19.6M Q1 '25: -41.2M Q2 '25: -39.2M Q3 '25: -22.2M Q4 '25: -30.6M Q1 '26: -47.9M Q2 '26: -35.6M Q4 '23 Q2 '24 Q4 '24 Q2 '25 Q4 '25 Q2 '26

Free Cash Flow Quarterly

-45M -30M -15M 0 15M 30M 45M Q4 '23: -16.1M Q4 '24: -19.8M Q3 '25: -22.3M Q4 '25: -30.7M Q4 '23 Q4 '24 Q3 '25 Q4 '25

Operating cash flow minus capital expenditure.

Shares Outstanding Quarterly

0 20M 40M 60M Q3 '23: 3M Q1 '24: 3M Q2 '24: 3M Q3 '24: 3M Q1 '25: 53.6M Q2 '25: 53.8M Q3 '25: 53.9M Q1 '26: 54.3M Q2 '26: 54.6M Q3 '23 Q2 '24 Q1 '25 Q3 '25 Q2 '26

Weighted average diluted, as the filer reports it for each period. An average cannot be added across periods, so this one is always shown per period the filer tagged rather than as a trailing year.

EPS TTM

-24.00 -16.00 -8.00 0.00 8.00 16.00 24.00 Q2 '24: -18.34 Q3 '24: -23.19 Q4 '24: -5.58 Q1 '25: -1.41 Q2 '25: 4.35 Q3 '25: 10.68 Q4 '25: -2.66 Q1 '26: -2.90 Q2 '26: -2.89 Q2 '24 Q4 '24 Q2 '25 Q4 '25 Q2 '26

The filer's own published earnings a share for each quarter, four quarters added up. The company page divides trailing net income by the share count instead, which lands within about 1% of this and is not the same sum, so the two are named differently rather than presented as one figure.