Protagonist Therapeutics, Inc (PTGX) · Insider trading
What Protagonist Therapeutics's directors, officers and largest holders bought and sold themselves, from the Form 4 each of them files with the SEC within two business days of a trade. Open-market purchases and sales first: those are the trades somebody chose to make at the market price.
Bought, 12 months
$0
0 insiders, 0 trades
Sold, 12 months
$87.71M
7 insiders, 59% under a plan
Net, 12 months
−$87.71M
bought less sold
Latest filing
2026-10-02
filings read to 2026-10-19
Who traded, two years
| Insider | Bought | Sold | Trades | Last trade | Holds after |
|---|---|---|---|---|---|
| Patel Dinesh V Ph DDirector, President and CEO | – | $61.41M | 20 | 2026-09-10 | 522,968 |
| Ali AsifChief Financial Officer | – | $17.17M | 11 | 2026-09-30 | 105,037 |
| Molina Arturo MDChief Medical Officer | – | $8.81M | 15 | 2026-03-26 | 84,115 |
| Waddill William D.Director | – | $6.29M | 9 | 2026-06-23 | 7,825 |
| Giraudo BryanDirector | – | $5.92M | 4 | 2026-05-08 | – |
| Gupta SuneelChief Development Officer | – | $5.64M | 2 | 2024-11-26 | 266,983 |
| Selick Harold eDirector | – | $2.52M | 1 | 2026-03-26 | 60,845 |
| Williams Lewis TDirector | – | $1.48M | 1 | 2026-02-17 | 7,825 |
Open-market purchases and sales
Newest first. “Plan” marks a trade made under a 10b5-1 plan set up in advance.
| Date | Insider | Trade | Shares | Price | Value | Holds after | Filing |
|---|---|---|---|---|---|---|---|
| 2026-09-30 | Ali AsifChief Financial Officer | Saleplan | 12,595 | 141.77 | $1.79M | 105,037 | Form 4 |
| 2026-09-30 | Ali AsifChief Financial Officer | Saleplan | 46,034 | 141.78 | $6.53M | 59,003 | Form 4 |
| 2026-09-10 | Patel Dinesh V Ph DDirector, President and CEO | Saleplan | 7,278 | 144.10 | $1.05M | 522,968 | Form 4 |
| 2026-09-09 | Patel Dinesh V Ph DDirector, President and CEO | Saleplan | 63,548 | 146.18 | $9.29M | 522,968 | Form 4 |
| 2026-09-08 | Patel Dinesh V Ph DDirector, President and CEO | Saleplan | 54,174 | 145.87 | $7.90M | 522,968 | Form 4 |
| 2026-08-11 | Patel Dinesh V Ph DDirector, President and CEO | Saleplan | 34,239 | 148.52 | $5.09M | 523,478 | Form 4 |
| 2026-08-10 | Patel Dinesh V Ph DDirector, President and CEO | Saleplan | 65,761 | 149.11 | $9.81M | 523,478 | Form 4 |
| 2026-06-23 | Waddill William D.Director | Saleplan | 9,000 | 117.94 | $1.06M | 7,825 | Form 4 |
| 2026-06-10 | Waddill William D.Director | Saleplan | 9,000 | 107.68 | $969,120 | 7,825 | Form 4 |
| 2026-05-29 | Waddill William D.Director | Saleplan | 9,000 | 99.64 | $896,760 | 7,825 | Form 4 |
| 2026-05-12 | Patel Dinesh V Ph DDirector, President and CEO | Saleplan | 75,000 | 100.12 | $7.51M | 523,478 | Form 4/A |
| 2026-05-08 | Giraudo BryanDirector | Saleindirect | 6,000 | 100.00 | $600,000 | 0 | Form 4 |
| 2026-05-08 | Giraudo BryanDirector | Sale | 5,130 | 100.00 | $513,000 | 12,695 | Form 4 |
| 2026-05-07 | Giraudo BryanDirector | Sale | 36,000 | 100.14 | $3.61M | 27,825 | Form 4 |
| 2026-05-07 | Giraudo BryanDirector | Saleindirect | 12,000 | 100.07 | $1.20M | 6,000 | Form 4 |
| 2026-04-20 | Ali AsifChief Financial Officer | Sale | 1,750 | 105.47 | $184,572 | 59,003 | Form 4 |
| 2026-03-26 | Ali AsifChief Financial Officer | Sale | 24,765 | 104.24 | $2.58M | 60,753 | Form 4 |
| 2026-03-26 | Selick Harold eDirector | Sale | 24,000 | 105.00 | $2.52M | 60,845 | Form 4 |
| 2026-03-26 | Molina Arturo MDChief Medical Officer | Sale | 15,000 | 104.79 | $1.57M | 84,115 | Form 4 |
| 2026-03-25 | Patel Dinesh V Ph DDirector, President and CEO | Sale | 54,641 | 101.00 | $5.52M | 524,938 | Form 4 |
| 2026-03-24 | Patel Dinesh V Ph DDirector, President and CEO | Sale | 59 | 101.00 | $5,959 | 524,938 | Form 4 |
| 2026-02-17 | Williams Lewis TDirector | Sale | 18,000 | 82.42 | $1.48M | 7,825 | Form 4 |
| 2026-02-06 | Waddill William D.Director | Sale | 20,000 | 83.68 | $1.67M | 7,825 | Form 4 |
| 2026-01-27 | Molina Arturo MDChief Medical Officer | Sale | 5,000 | 82.00 | $410,000 | 84,115 | Form 4 |
| 2026-01-27 | Ali AsifChief Financial Officer | Sale | 28,000 | 83.13 | $2.33M | 78,523 | Form 4 |
| 2026-01-27 | Ali AsifChief Financial Officer | Sale | 18,203 | 83.14 | $1.51M | 60,320 | Form 4 |
| 2026-01-27 | Patel Dinesh V Ph DDirector, President and CEO | Sale | 4,068 | 83.19 | $338,417 | 574,505 | Form 4 |
| 2026-01-26 | Molina Arturo MDChief Medical Officer | Sale | 5,000 | 82.28 | $411,400 | 84,115 | Form 4 |
| 2026-01-26 | Patel Dinesh V Ph DDirector, President and CEO | Sale | 10,685 | 84.00 | $897,540 | 574,505 | Form 4 |
| 2026-01-26 | Patel Dinesh V Ph DDirector, President and CEO | Sale | 14,205 | 84.05 | $1.19M | 574,505 | Form 4 |
| 2026-01-23 | Molina Arturo MDChief Medical Officer | Sale | 13,151 | 82.42 | $1.08M | 84,115 | Form 4 |
| 2026-01-23 | Patel Dinesh V Ph DDirector, President and CEO | Sale | 19,315 | 84.59 | $1.63M | 574,505 | Form 4 |
| 2026-01-20 | Ali AsifChief Financial Officer | Sale | 8,588 | 82.48 | $708,338 | 78,077 | Form 4 |
| 2026-01-20 | Patel Dinesh V Ph DDirector, President and CEO | Sale | 34,438 | 82.48 | $2.84M | 580,505 | Form 4 |
| 2026-01-20 | Molina Arturo MDChief Medical Officer | Sale | 9,514 | 82.48 | $784,715 | 97,266 | Form 4 |
| 2025-11-17 | Molina Arturo MDChief Medical Officer | Sale | 2,712 | 84.77 | $229,896 | 81,180 | Form 4 |
| 2025-10-10 | Waddill William D.Director | Saleplan | 4,000 | 69.25 | $277,000 | 13,130 | Form 4 |
| 2025-10-10 | Waddill William D.Director | Saleplan | 8,000 | 87.81 | $702,480 | 5,130 | Form 4 |
| 2025-09-22 | Waddill William D.Director | Saleplan | 4,000 | 64.25 | $257,000 | 5,130 | Form 4 |
| 2025-08-27 | Waddill William D.Director | Saleplan | 4,000 | 59.25 | $237,000 | 9,130 | Form 4 |
23 more
| 2025-07-25 | Patel Dinesh V Ph DDirector, President and CEO | Sale | 10,415 | 54.78 | $570,534 | 520,603 | Form 4 |
| 2025-07-23 | Patel Dinesh V Ph DDirector, President and CEO | Sale | 17,520 | 54.79 | $959,921 | 531,018 | Form 4 |
| 2025-07-22 | Patel Dinesh V Ph DDirector, President and CEO | Sale | 22,065 | 55.05 | $1.21M | 548,538 | Form 4 |
| 2025-07-21 | Patel Dinesh V Ph DDirector, President and CEO | Sale | 12,859 | 54.86 | $705,445 | 570,603 | Form 4 |
| 2025-06-10 | Molina Arturo MDChief Medical Officer | Sale | 10,000 | 57.03 | $570,300 | 83,892 | Form 4 |
| 2025-06-09 | Molina Arturo MDChief Medical Officer | Sale | 10,000 | 55.51 | $555,100 | 83,892 | Form 4 |
| 2025-04-22 | Ali AsifChief Financial Officer | Sale | 1,756 | 46.00 | $80,776 | 61,065 | Form 4 |
| 2025-03-17 | Waddill William D.Director | Saleplan | 4,000 | 54.25 | $217,000 | 13,130 | Form 4 |
| 2025-03-13 | Molina Arturo MDChief Medical Officer | Sale | 30,514 | 55.74 | $1.70M | 83,892 | Form 4 |
| 2025-03-12 | Ali AsifChief Financial Officer | Sale | 24,903 | 58.73 | $1.46M | 62,821 | Form 4 |
| 2025-02-19 | Patel Dinesh V Ph DDirector, President and CEO | Sale | 5,359 | 38.18 | $204,607 | 540,260 | Form 4 |
| 2025-01-16 | Ali AsifChief Financial Officer | Sale | 1,317 | – | – | 65,422 | Form 4 |
| 2025-01-16 | Ali AsifChief Financial Officer | Sale | 2,601 | – | – | 62,821 | Form 4 |
| 2025-01-16 | Molina Arturo MDChief Medical Officer | Sale | 388 | – | – | 87,144 | Form 4 |
| 2025-01-16 | Molina Arturo MDChief Medical Officer | Sale | 3,252 | – | – | 83,892 | Form 4 |
| 2024-11-27 | Molina Arturo MDChief Medical Officer | Sale | 10,000 | 44.50 | $445,000 | 46,444 | Form 4 |
| 2024-11-27 | Molina Arturo MDChief Medical Officer | Sale | 16,000 | 44.83 | $717,280 | 46,444 | Form 4 |
| 2024-11-26 | Patel Dinesh V Ph DDirector, President and CEO | Sale | 21,480 | 46.25 | $993,450 | 408,455 | Form 4 |
| 2024-11-26 | Gupta SuneelChief Development Officer | Sale | 19,191 | 45.50 | $873,190 | 266,983 | Form 4 |
| 2024-11-26 | Molina Arturo MDChief Medical Officer | Sale | 5,529 | 45.60 | $252,122 | 46,444 | Form 4 |
| 2024-11-25 | Patel Dinesh V Ph DDirector, President and CEO | Sale | 78,520 | 46.96 | $3.69M | 435,208 | Form 4 |
| 2024-11-25 | Gupta SuneelChief Development Officer | Sale | 103,437 | 46.04 | $4.76M | 256,174 | Form 4 |
| 2024-11-15 | Molina Arturo MDChief Medical Officer | Sale | 1,906 | 40.98 | $78,108 | 46,444 | Form 4 |
Grants, exercises and other transactions
Pay, tax and paperwork rather than a choice to trade at the market price. Two years.
51 × option exercise17 × grant or award11 × gift1 × shares withheld for tax
Show them
| Date | Insider | What | Shares | Price | Holds after | Filing |
|---|---|---|---|---|---|---|
| 2026-09-30 | Ali AsifChief Financial Officer | Option exercise M | +9,229 | 38.98 | 68,232 | Form 4 |
| 2026-09-30 | Ali AsifChief Financial Officer | Option exercise M | +28,438 | 23.42 | 96,670 | Form 4 |
| 2026-09-30 | Ali AsifChief Financial Officer | Option exercise M | +15,650 | 19.19 | 112,320 | Form 4 |
| 2026-09-30 | Ali AsifChief Financial Officer | Option exercise M | +5,312 | 12.17 | 117,632 | Form 4 |
| 2026-09-10 | Patel Dinesh V Ph DDirector, President and CEO | Option exercise M | +7,278 | 21.58 | 530,246 | Form 4 |
| 2026-09-09 | Patel Dinesh V Ph DDirector, President and CEO | Option exercise M | +63,548 | 21.58 | 586,516 | Form 4 |
| 2026-09-08 | Patel Dinesh V Ph DDirector, President and CEO | Option exercise M | +54,174 | 21.58 | 577,142 | Form 4 |
| 2026-09-03 | Patel Dinesh V Ph DDirector, President and CEO | Gift G | −510 | – | 522,968 | Form 4 |
| 2026-08-11 | Patel Dinesh V Ph DDirector, President and CEO | Option exercise M | +34,239 | 21.58 | 557,717 | Form 4 |
| 2026-08-10 | Patel Dinesh V Ph DDirector, President and CEO | Option exercise M | +65,761 | 21.58 | 589,239 | Form 4 |
| 2026-06-23 | Waddill William D.Director | Option exercise M | +9,000 | 16.54 | 16,825 | Form 4 |
| 2026-06-10 | Waddill William D.Director | Option exercise M | +3,000 | 11.80 | 10,825 | Form 4 |
| 2026-06-10 | Waddill William D.Director | Option exercise M | +6,000 | 16.54 | 16,825 | Form 4 |
| 2026-05-29 | Waddill William D.Director | Option exercise M | +9,000 | 11.80 | 16,825 | Form 4 |
| 2026-05-12 | Patel Dinesh V Ph DDirector, President and CEO | Option exercise M | +75,000 | 21.58 | 598,478 | Form 4/A |
| 2026-05-07 | Giraudo BryanDirector | Option exercise M | +24,000 | 6.45 | 31,825 | Form 4 |
| 2026-05-07 | Giraudo BryanDirector | Option exercise M | +12,000 | 6.98 | 43,825 | Form 4 |
| 2026-04-23 | Patel Dinesh V Ph DDirector, President and CEO | Gift G | −1,460 | – | 523,478 | Form 4 |
| 2026-03-26 | Ali AsifChief Financial Officer | Option exercise M | +19,500 | 19.19 | 80,253 | Form 4 |
| 2026-03-26 | Ali AsifChief Financial Officer | Option exercise M | +5,265 | 12.17 | 85,518 | Form 4 |
| 2026-03-26 | Selick Harold eDirector | Option exercise M | +24,000 | 12.88 | 84,845 | Form 4 |
| 2026-03-26 | Molina Arturo MDChief Medical Officer | Option exercise M | +15,000 | 8.04 | 99,115 | Form 4 |
| 2026-03-25 | Patel Dinesh V Ph DDirector, President and CEO | Option exercise M | +54,641 | 8.58 | 579,579 | Form 4 |
| 2026-03-24 | Patel Dinesh V Ph DDirector, President and CEO | Option exercise M | +59 | 8.58 | 524,997 | Form 4 |
| 2026-03-23 | Patel Dinesh V Ph DDirector, President and CEO | Gift G | −50,000 | – | 524,938 | Form 4 |
| 2026-02-17 | Williams Lewis TDirector | Option exercise M | +18,000 | 10.84 | 25,825 | Form 4 |
| 2026-02-06 | Waddill William D.Director | Option exercise M | +20,000 | 8.31 | 27,825 | Form 4 |
| 2026-01-27 | Molina Arturo MDChief Medical Officer | Option exercise M | +5,000 | 8.04 | 89,115 | Form 4 |
| 2026-01-27 | Ali AsifChief Financial Officer | Option exercise M | +16,000 | 19.19 | 94,523 | Form 4 |
| 2026-01-27 | Ali AsifChief Financial Officer | Option exercise M | +12,000 | 12.17 | 106,523 | Form 4 |
| 2026-01-27 | Patel Dinesh V Ph DDirector, President and CEO | Option exercise M | +4,068 | 21.58 | 578,573 | Form 4 |
| 2026-01-26 | Molina Arturo MDChief Medical Officer | Option exercise M | +5,000 | 8.04 | 89,115 | Form 4 |
| 2026-01-26 | Patel Dinesh V Ph DDirector, President and CEO | Option exercise M | +10,685 | 4.21 | 585,190 | Form 4 |
| 2026-01-26 | Patel Dinesh V Ph DDirector, President and CEO | Option exercise M | +14,205 | 21.58 | 588,710 | Form 4 |
| 2026-01-23 | Patel Dinesh V Ph DDirector, President and CEO | Gift G | −6,000 | – | 574,505 | Form 4 |
| 2026-01-23 | Patel Dinesh V Ph DDirector, President and CEO | Option exercise M | +19,315 | 4.21 | 593,820 | Form 4 |
| 2026-01-09 | Selick Harold eDirector | Option exercise M | +14,299 | 4.21 | 60,845 | Form 4 |
| 2026-01-02 | Molina Arturo MDChief Medical Officer | Grant or award A | +25,600 | – | 106,780 | Form 4 |
| 2026-01-02 | Ali AsifChief Financial Officer | Grant or award A | +25,600 | – | 86,665 | Form 4 |
| 2026-01-02 | Patel Dinesh V Ph DDirector, President and CEO | Grant or award A | +95,400 | – | 614,943 | Form 4 |
| 2026-01-02 | O'Dowd Sarah ADirector | Grant or award A | +2,695 | – | 7,825 | Form 4 |
| 2026-01-02 | Williams Lewis TDirector | Grant or award A | +2,695 | – | 7,825 | Form 4 |
| 2026-01-02 | Giraudo BryanDirector | Grant or award A | +2,695 | – | 17,825 | Form 4 |
| 2026-01-02 | Waddill William D.Director | Grant or award A | +2,695 | – | 7,825 | Form 4 |
| 2026-01-02 | Selick Harold eDirector | Grant or award A | +2,695 | – | 46,546 | Form 4 |
| 2025-11-21 | Patel Dinesh V Ph DDirector, President and CEO | Gift G | −440 | – | 519,543 | Form 4 |
| 2025-10-10 | Waddill William D.Director | Option exercise M | +12,000 | 6.98 | 17,130 | Form 4 |
| 2025-09-16 | Patel Dinesh V Ph DDirector, President and CEO | Gift G | −620 | – | 519,983 | Form 4 |
| 2025-07-21 | Patel Dinesh V Ph DDirector, President and CEO | Grant or award A | +25,000 | – | 583,462 | Form 4 |
| 2025-07-16 | Patel Dinesh V Ph DDirector, President and CEO | Gift G | −5,000 | – | 558,462 | Form 4 |
| 2025-06-16 | Patel Dinesh V Ph DDirector, President and CEO | Gift G | −685 | – | 562,905 | Form 4 |
| 2025-06-13 | Patel Dinesh V Ph DDirector, President and CEO | Gift G | −670 | – | 563,590 | Form 4 |
| 2025-06-10 | Molina Arturo MDChief Medical Officer | Option exercise M | +10,000 | 8.04 | 93,892 | Form 4 |
| 2025-06-09 | Molina Arturo MDChief Medical Officer | Option exercise M | +10,000 | 8.04 | 93,892 | Form 4 |
| 2025-04-28 | Selick Harold eDirector | Option exercise M | +10,725 | 1.16 | 43,851 | Form 4 |
| 2025-03-13 | Molina Arturo MDChief Medical Officer | Option exercise M | +28,437 | 23.42 | 112,329 | Form 4 |
| 2025-03-13 | Molina Arturo MDChief Medical Officer | Option exercise M | +2,077 | 38.98 | 114,406 | Form 4 |
| 2025-03-12 | Ali AsifChief Financial Officer | Option exercise M | +15,203 | 12.17 | 78,024 | Form 4 |
| 2025-03-12 | Ali AsifChief Financial Officer | Option exercise M | +9,700 | 19.19 | 87,724 | Form 4 |
| 2025-03-05 | Patel Dinesh V Ph DDirector, President and CEO | Option exercise M | +24,000 | 4.21 | 564,260 | Form 4 |
| 2025-01-15 | Patel Dinesh V Ph DDirector, President and CEO | Shares withheld for tax F | −12,636 | – | 545,619 | Form 4 |
| 2025-01-02 | Ali AsifChief Financial Officer | Grant or award A | +31,779 | – | 66,739 | Form 4 |
| 2025-01-02 | Molina Arturo MDChief Medical Officer | Grant or award A | +41,088 | – | 87,532 | Form 4 |
| 2025-01-02 | Giraudo BryanDirector | Grant or award A | +5,130 | – | 15,130 | Form 4 |
| 2025-01-02 | Patel Dinesh V Ph DDirector, President and CEO | Grant or award A | +149,800 | – | 558,255 | Form 4 |
| 2025-01-02 | Selick Harold eDirector | Grant or award A | +5,130 | – | 33,126 | Form 4 |
| 2025-01-02 | Williams Lewis TDirector | Grant or award A | +5,130 | – | 5,130 | Form 4 |
| 2025-01-02 | O'Dowd Sarah ADirector | Grant or award A | +5,130 | – | 5,130 | Form 4 |
| 2025-01-02 | Waddill William D.Director | Grant or award A | +5,130 | – | 17,130 | Form 4 |
| 2024-11-27 | Molina Arturo MDChief Medical Officer | Option exercise M | +10,000 | 8.04 | 56,444 | Form 4 |
| 2024-11-27 | Molina Arturo MDChief Medical Officer | Option exercise M | +16,000 | 8.04 | 62,444 | Form 4 |
| 2024-11-26 | Gupta SuneelChief Development Officer | Option exercise M | +30,000 | 12.17 | 286,174 | Form 4 |
| 2024-11-26 | Gupta SuneelChief Development Officer | Option exercise M | +450 | 12.17 | 267,433 | Form 4 |
| 2024-11-26 | Molina Arturo MDChief Medical Officer | Option exercise M | +5,529 | 8.04 | 51,973 | Form 4 |
| 2024-11-25 | Patel Dinesh V Ph DDirector, President and CEO | Gift G | −7,000 | – | 428,208 | Form 4 |
| 2024-11-25 | Patel Dinesh V Ph DDirector, President and CEO | Option exercise M | +1,727 | 21.58 | 429,935 | Form 4 |
| 2024-11-25 | Gupta SuneelChief Development Officer | Option exercise M | +45,000 | 7.38 | 229,611 | Form 4 |
| 2024-11-25 | Gupta SuneelChief Development Officer | Option exercise M | +45,000 | 8.02 | 274,611 | Form 4 |
| 2024-11-25 | Gupta SuneelChief Development Officer | Option exercise M | +85,000 | 7.80 | 359,611 | Form 4 |
| 2024-11-19 | Patel Dinesh V Ph DDirector, President and CEO | Gift G | −1,000 | – | 513,415 | Form 4 |
How to read it
- Buy, sale
- Code P and S on the form: shares bought or sold in the market, at the market price. The other codes are mostly pay (a grant, an option exercised) or tax (shares the company withheld), and say little about what the insider thinks of the price.
- Plan
- A sale or purchase under a Rule 10b5-1 plan, set up in advance and running on its own schedule. Since April 2023 the form has a box for it. Much executive selling is planned and says more about diversifying than about the company.
- Holds after
- The shares the insider still held after the trade, in the form the trade was in (directly, or indirectly through a trust or a fund).
- Value
- Shares times the price the form reports, which is often an average over several fills on the day.
Read from the SEC's own quarterly data sets of Forms 3, 4 and 5, and from each day's filings since the last one. A correcting amendment replaces the lines it restates. Every row links to its filing. None of this is advice: insiders sell for many reasons, and buy for fewer.