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Praxis Precision Medicines, Inc. (PRAX) · Insider trading

What Praxis Precision Medicines's directors, officers and largest holders bought and sold themselves, from the Form 4 each of them files with the SEC within two business days of a trade. Open-market purchases and sales first: those are the trades somebody chose to make at the market price.

Bought, 12 months
$0
0 insiders, 0 trades
Sold, 12 months
$11.08M
3 insiders, 33% under a plan
Net, 12 months
−$11.08M
bought less sold
Latest filing
2026-07-08
filings read to 2026-10-19

Bought and sold at the market, by month

Two years. Purchases above the line, sales below, in dollars.

2024-11: $1.09M sold 2025-01 2025-07 2025-10: $33.20M sold 2025-11: $7.46M sold 2026-01 2026-06: $3.61M sold 2026-07
Bought Sold Largest month: $33.20M

Who traded, two years

InsiderBoughtSold TradesLast tradeHolds after
Atchinson Robert10% owner – $33.20M 10 2025-10-16 –
Nemiroff AlexGeneral Counsel and Secretary – $5.51M 5 2025-11-20 44,248
DeSimone JillDirector – $3.61M 12 2026-06-24 13,927
Mastrocola LaurenPrincipal Accounting Officer – $3.04M 3 2025-11-20 12,587

Open-market purchases and sales

Newest first. “Plan” marks a trade made under a 10b5-1 plan set up in advance.

DateInsiderTradeShares PriceValueHolds afterFiling
2026-06-24 DeSimone JillDirector Saleplan 10 301.44 $3,014 13,927 Form 4
2026-06-24 DeSimone JillDirector Saleplan 120 303.13 $36,376 13,807 Form 4
2026-06-24 DeSimone JillDirector Saleplan 320 305.31 $97,699 13,487 Form 4
2026-06-24 DeSimone JillDirector Saleplan 683 306.77 $209,524 12,804 Form 4
2026-06-24 DeSimone JillDirector Saleplan 1,240 308.24 $382,218 11,564 Form 4
2026-06-24 DeSimone JillDirector Saleplan 999 309.38 $309,071 10,565 Form 4
2026-06-24 DeSimone JillDirector Saleplan 1,750 310.89 $544,058 8,815 Form 4
2026-06-24 DeSimone JillDirector Saleplan 2,854 311.91 $890,191 5,961 Form 4
2026-06-24 DeSimone JillDirector Saleplan 1,004 312.83 $314,081 4,957 Form 4
2026-06-24 DeSimone JillDirector Saleplan 504 313.66 $158,085 4,453 Form 4
2026-06-24 DeSimone JillDirector Saleplan 1,279 314.90 $402,757 3,174 Form 4
2026-06-24 DeSimone JillDirector Saleplan 837 315.71 $264,249 2,337 Form 4
2025-11-20 Mastrocola LaurenPrincipal Accounting Officer Sale 11,455 191.96 $2.20M 12,587 Form 4
2025-11-20 Mastrocola LaurenPrincipal Accounting Officer Sale 2,145 192.71 $413,363 10,442 Form 4
2025-11-20 Nemiroff AlexGeneral Counsel and Secretary Sale 1,714 190.86 $327,134 44,248 Form 4
2025-11-20 Nemiroff AlexGeneral Counsel and Secretary Sale 13,339 192.53 $2.57M 30,909 Form 4
2025-11-20 Nemiroff AlexGeneral Counsel and Secretary Sale 977 193.23 $188,786 29,932 Form 4
2025-11-20 Nemiroff AlexGeneral Counsel and Secretary Sale 9,100 194.30 $1.77M 20,832 Form 4
2025-10-16 Atchinson Robert10% ownerwith Gross Phillip, Adage Capital Management, L.P. Saleindirect 12,600 90.00 $1.13M 2,361,485 Form 4
2025-10-16 Atchinson Robert10% ownerwith Gross Phillip, Adage Capital Management, L.P. Saleindirect 447 91.04 $40,695 2,361,038 Form 4
2025-10-16 Atchinson Robert10% ownerwith Gross Phillip, Adage Capital Management, L.P. Saleindirect 1,363 92.03 $125,437 2,359,675 Form 4
2025-10-16 Atchinson Robert10% ownerwith Gross Phillip, Adage Capital Management, L.P. Saleindirect 559 100.11 $55,961 2,359,116 Form 4
2025-10-16 Atchinson Robert10% ownerwith Gross Phillip, Adage Capital Management, L.P. Saleindirect 27,287 101.00 $2.76M 2,331,829 Form 4
2025-10-16 Atchinson Robert10% ownerwith Gross Phillip, Adage Capital Management, L.P. Saleindirect 250,000 104.31 $26.08M 2,081,829 Form 4
2025-10-16 Atchinson Robert10% ownerwith Gross Phillip, Adage Capital Management, L.P. Saleindirect 1,661 130.10 $216,096 2,080,168 Form 4
2025-10-16 Atchinson Robert10% ownerwith Gross Phillip, Adage Capital Management, L.P. Saleindirect 487 131.64 $64,109 2,079,681 Form 4
2025-10-16 Atchinson Robert10% ownerwith Gross Phillip, Adage Capital Management, L.P. Saleindirect 308 132.19 $40,715 2,079,373 Form 4
2025-10-16 Atchinson Robert10% ownerwith Gross Phillip, Adage Capital Management, L.P. Saleindirect 19,198 140.00 $2.69M 2,060,175 Form 4
2024-11-14 Mastrocola LaurenPrincipal Accounting Officer Sale 5,188 81.78 $424,302 5,613 Form 4
2024-11-14 Nemiroff AlexGeneral Counsel and Secretary Sale 8,239 80.20 $660,794 10,301 Form 4

Grants, exercises and other transactions

Pay, tax and paperwork rather than a choice to trade at the market price. Two years.

31 × grant or award23 × shares withheld for tax19 × option exercise3 × gift
Show them
DateInsiderWhatShares PriceHolds afterFiling
2026-07-08 Souza MarcioDirector, Chief Executive Officer Gift G −20,521 – 56,495 Form 4
2026-07-08 Souza MarcioDirector, Chief Executive Officer Gift G −2,600 – 0 Form 4
2026-06-24 DeSimone JillDirector Option exercise M +8,566 44.25 10,903 Form 4
2026-06-24 DeSimone JillDirector Option exercise M +3,034 147.30 13,937 Form 4
2026-06-10 Norden GregoryDirector Grant or award A +1,371 – 1,559 Form 4
2026-06-10 Kindler Jeffrey BDirector Grant or award A +1,371 – 2,537 Form 4
2026-06-10 Mitchell Dean JDirector Grant or award A +1,371 – 18,622 Form 4
2026-06-10 Cudkowicz Merit EsterDirector Grant or award A +1,371 – 1,371 Form 4
2026-06-10 DeSimone JillDirector Grant or award A +1,371 – 2,337 Form 4
2026-06-10 Young William DDirector Grant or award A +1,371 – 3,269 Form 4
2026-06-10 Chodakewitz JeffreyDirector Grant or award A +1,371 – 1,371 Form 4
2026-06-10 Arbuckle Stuart ADirector Grant or award A +1,371 – 2,537 Form 4
2026-05-14 Kelly Timothy EdwinChief Financial Officer Grant or award A +121 167.94 31,167 Form 4
2026-05-14 Souza MarcioDirector, Chief Executive Officer Grant or award A +126 167.94 77,016 Form 4
2026-05-14 Sniecinski MeganChief Operating Officer Grant or award A +89 167.94 28,664 Form 4
2026-05-14 Mastrocola LaurenPrincipal Accounting Officer Grant or award A +127 167.94 13,573 Form 4
2026-05-14 Nemiroff AlexGeneral Counsel and Secretary Grant or award A +78 167.94 26,011 Form 4
2026-02-06 Kindler Jeffrey BDirector Grant or award A +688 – 688 Form 4
2026-02-06 Kindler Jeffrey BDirector Grant or award A +478 – 1,166 Form 4
2026-02-06 Arbuckle Stuart ADirector Grant or award A +688 – 688 Form 4
2026-02-06 Arbuckle Stuart ADirector Grant or award A +478 – 1,166 Form 4
2026-01-12 Sniecinski MeganChief Operating Officer Shares withheld for tax F −885 275.74 28,530 Form 4
2026-01-12 Mastrocola LaurenPrincipal Accounting Officer Shares withheld for tax F −344 275.74 13,446 Form 4
2026-01-12 Nemiroff AlexGeneral Counsel and Secretary Shares withheld for tax F −768 275.74 25,933 Form 4
2026-01-12 Kelly Timothy EdwinChief Financial Officer Shares withheld for tax F −943 275.74 31,046 Form 4
2026-01-10 Souza MarcioDirector, Chief Executive Officer Shares withheld for tax F −4,252 288.45 76,890 Form 4
2026-01-10 Kelly Timothy EdwinChief Financial Officer Shares withheld for tax F −1,335 288.45 31,989 Form 4
2026-01-10 Nemiroff AlexGeneral Counsel and Secretary Shares withheld for tax F −917 288.45 26,701 Form 4
2026-01-10 Sniecinski MeganChief Operating Officer Shares withheld for tax F −1,087 288.45 29,415 Form 4
2026-01-10 Mastrocola LaurenPrincipal Accounting Officer Shares withheld for tax F −367 288.45 13,790 Form 4
2026-01-08 Souza MarcioDirector, Chief Executive Officer Grant or award A +27,640 – 81,142 Form 4
2026-01-08 Kelly Timothy EdwinChief Financial Officer Grant or award A +8,800 – 33,324 Form 4
2026-01-08 Nemiroff AlexGeneral Counsel and Secretary Grant or award A +6,875 – 27,618 Form 4
2026-01-08 Sniecinski MeganChief Operating Officer Grant or award A +9,625 – 30,502 Form 4
2026-01-08 Mastrocola LaurenPrincipal Accounting Officer Grant or award A +3,750 – 14,157 Form 4
2026-01-07 Souza MarcioDirector, Chief Executive Officer Shares withheld for tax F −405 292.63 53,502 Form 4
2026-01-07 Mastrocola LaurenPrincipal Accounting Officer Shares withheld for tax F −35 292.63 10,407 Form 4
2026-01-07 Nemiroff AlexGeneral Counsel and Secretary Shares withheld for tax F −89 292.63 20,743 Form 4
2026-01-07 Kelly Timothy EdwinChief Financial Officer Shares withheld for tax F −139 292.63 24,524 Form 4
2025-12-30 Souza MarcioDirector, Chief Executive Officer Gift G −400 – 2,600 Form 4
2025-11-20 Mastrocola LaurenPrincipal Accounting Officer Option exercise M +1,047 49.50 11,489 Form 4
2025-11-20 Mastrocola LaurenPrincipal Accounting Officer Option exercise M +508 83.85 11,997 Form 4
2025-11-20 Mastrocola LaurenPrincipal Accounting Officer Option exercise M +1,557 133.65 13,554 Form 4
2025-11-20 Mastrocola LaurenPrincipal Accounting Officer Option exercise M +2,680 43.37 16,234 Form 4
2025-11-20 Mastrocola LaurenPrincipal Accounting Officer Option exercise M +207 44.40 16,441 Form 4
2025-11-20 Mastrocola LaurenPrincipal Accounting Officer Option exercise M +2,351 44.40 18,792 Form 4
2025-11-20 Mastrocola LaurenPrincipal Accounting Officer Option exercise M +5,250 56.94 24,042 Form 4
2025-11-20 Nemiroff AlexGeneral Counsel and Secretary Option exercise M +1,714 83.85 22,546 Form 4
2025-11-20 Nemiroff AlexGeneral Counsel and Secretary Option exercise M +6,230 133.65 28,776 Form 4
2025-11-20 Nemiroff AlexGeneral Counsel and Secretary Option exercise M +2,434 44.40 31,210 Form 4
2025-11-20 Nemiroff AlexGeneral Counsel and Secretary Option exercise M +5,652 44.40 36,862 Form 4
2025-11-20 Nemiroff AlexGeneral Counsel and Secretary Option exercise M +9,100 56.94 45,962 Form 4
2025-11-14 Kelly Timothy EdwinChief Financial Officer Grant or award A +384 31.62 24,663 Form 4
2025-09-24 Mitchell Dean JDirector Option exercise M +1,932 14.36 6,932 Form 4
2025-09-24 Mitchell Dean JDirector Option exercise M +8,566 44.25 15,498 Form 4
2025-09-24 Mitchell Dean JDirector Option exercise M +1,753 44.04 17,251 Form 4
2025-05-14 Kelly Timothy EdwinChief Financial Officer Grant or award A +249 31.54 24,279 Form 4
2025-05-14 Souza MarcioDirector, Chief Executive Officer Grant or award A +348 31.54 53,907 Form 4
2025-02-12 Souza MarcioDirector, Chief Executive Officer Shares withheld for tax F −401 85.40 53,559 Form 4
2025-02-12 Mastrocola LaurenPrincipal Accounting Officer Shares withheld for tax F −40 85.40 10,442 Form 4
2025-02-12 Nemiroff AlexGeneral Counsel and Secretary Shares withheld for tax F −51 85.40 20,832 Form 4
2025-01-12 Nemiroff AlexGeneral Counsel and Secretary Shares withheld for tax F −579 63.15 20,883 Form 4
2025-01-12 Kelly Timothy EdwinChief Financial Officer Shares withheld for tax F −676 63.15 24,030 Form 4
2025-01-12 Mastrocola LaurenPrincipal Accounting Officer Shares withheld for tax F −390 63.15 10,482 Form 4
2025-01-10 Nemiroff AlexGeneral Counsel and Secretary Grant or award A +11,250 – 21,462 Form 4
2025-01-10 Kelly Timothy EdwinChief Financial Officer Grant or award A +12,500 – 24,706 Form 4
2025-01-10 Souza MarcioDirector, Chief Executive Officer Grant or award A +37,500 – 53,960 Form 4
2025-01-10 Mastrocola LaurenPrincipal Accounting Officer Grant or award A +5,000 – 10,872 Form 4
2025-01-07 Kelly Timothy EdwinChief Financial Officer Shares withheld for tax F −139 77.52 12,206 Form 4
2025-01-07 Nemiroff AlexGeneral Counsel and Secretary Shares withheld for tax F −89 77.52 10,212 Form 4
2025-01-07 Mastrocola LaurenPrincipal Accounting Officer Shares withheld for tax F −35 77.52 5,872 Form 4
2025-01-07 Souza MarcioDirector, Chief Executive Officer Shares withheld for tax F −434 77.52 16,460 Form 4
2024-11-14 Kelly Timothy EdwinChief Financial Officer Grant or award A +205 37.40 12,345 Form 4
2024-11-14 Mastrocola LaurenPrincipal Accounting Officer Grant or award A +294 37.40 5,907 Form 4
2024-11-14 Mastrocola LaurenPrincipal Accounting Officer Option exercise M +4,374 56.94 10,801 Form 4
2024-11-14 Nemiroff AlexGeneral Counsel and Secretary Option exercise M +7,583 56.94 18,540 Form 4

How to read it

Buy, sale
Code P and S on the form: shares bought or sold in the market, at the market price. The other codes are mostly pay (a grant, an option exercised) or tax (shares the company withheld), and say little about what the insider thinks of the price.
Plan
A sale or purchase under a Rule 10b5-1 plan, set up in advance and running on its own schedule. Since April 2023 the form has a box for it. Much executive selling is planned and says more about diversifying than about the company.
Holds after
The shares the insider still held after the trade, in the form the trade was in (directly, or indirectly through a trust or a fund).
Value
Shares times the price the form reports, which is often an average over several fills on the day.

Read from the SEC's own quarterly data sets of Forms 3, 4 and 5, and from each day's filings since the last one. A correcting amendment replaces the lines it restates. Every row links to its filing. None of this is advice: insiders sell for many reasons, and buy for fewer.

Praxis Precision Medicines's scores and multiples ›