BeOne Medicines Ltd. (ONC) · Insider trading
What BeOne Medicines's directors, officers and largest holders bought and sold themselves, from the Form 4 each of them files with the SEC within two business days of a trade. Open-market purchases and sales first: those are the trades somebody chose to make at the market price.
Bought, 12 months
$0
0 insiders, 0 trades
Sold, 12 months
$369.20M
12 insiders, 96% under a plan
Net, 12 months
−$369.20M
bought less sold
Latest filing
2026-10-02
filings read to 2026-10-19
Who traded, two years
| Insider | Bought | Sold | Trades | Last trade | Holds after |
|---|---|---|---|---|---|
| Hillhouse Investment Management, Ltd.10% owner | – | $3.57B | 1 | 2024-12-02 | – |
| Oyler JohnDirector, Chief Executive Officer | – | $407.13M | 181 | 2026-08-12 | 52,912 |
| Baker JulianDirector | – | $385.00M | 10 | 2026-05-22 | – |
| Wang XiaodongDirector, Other | – | $102.44M | 97 | 2026-09-28 | 30,868 |
| Wu XiaobinPresident and COO | – | $78.19M | 59 | 2026-08-25 | 0 |
| Lee Chan HenrySVP, General Counsel | – | $16.15M | 39 | 2026-09-30 | 0 |
| Wang LaiPresident, Global Head of R&D | – | $6.77M | 24 | 2026-06-23 | 0 |
| Sanders Corazon (Corsee) D.Director | – | $1.86M | 4 | 2026-05-22 | 0 |
| Rosenberg AaronChief Financial Officer | – | $870,110 | 3 | 2026-08-03 | 0 |
| Ball Titus B.Principal Accounting Officer | – | $201,826 | 7 | 2026-09-01 | 0 |
| Dugan MargaretDirector | – | $65,635 | 1 | 2026-05-22 | 0 |
| Riva AlessandroDirector | – | $65,616 | 1 | 2026-05-22 | 0 |
| Yi QingqingDirector | – | $65,596 | 1 | 2026-06-01 | 0 |
Open-market purchases and sales
Newest first. “Plan” marks a trade made under a 10b5-1 plan set up in advance.
| Date | Insider | Trade | Shares | Price | Value | Holds after | Filing |
|---|---|---|---|---|---|---|---|
| 2026-09-30 | Lee Chan HenrySVP, General Counsel | Saleplan | 1,115 | 375.00 | $418,125 | 0 | Form 4 |
| 2026-09-28 | Wang XiaodongDirector, Other | Saleplan | 160 | 356.97 | $57,115 | 30,868 | Form 4 |
| 2026-09-28 | Wang XiaodongDirector, Other | Saleplan | 120 | 358.71 | $43,045 | 30,748 | Form 4 |
| 2026-09-28 | Wang XiaodongDirector, Other | Saleplan | 40 | 359.16 | $14,366 | 30,708 | Form 4 |
| 2026-09-28 | Wang XiaodongDirector, Other | Saleplan | 2,241 | 361.05 | $809,113 | 28,467 | Form 4 |
| 2026-09-28 | Wang XiaodongDirector, Other | Saleplan | 4,239 | 362.17 | $1.54M | 24,228 | Form 4 |
| 2026-09-28 | Wang XiaodongDirector, Other | Saleplan | 3,499 | 363.10 | $1.27M | 20,729 | Form 4 |
| 2026-09-28 | Wang XiaodongDirector, Other | Saleplan | 3,419 | 364.07 | $1.24M | 17,310 | Form 4 |
| 2026-09-28 | Wang XiaodongDirector, Other | Saleplan | 2,047 | 365.85 | $748,895 | 15,263 | Form 4 |
| 2026-09-28 | Wang XiaodongDirector, Other | Saleplan | 14,525 | 366.58 | $5.32M | 738 | Form 4 |
| 2026-09-28 | Wang XiaodongDirector, Other | Saleplan | 738 | 367.23 | $271,016 | 0 | Form 4 |
| 2026-09-08 | Wang XiaodongDirector, Other | Saleplan | 1,181 | 345.38 | $407,894 | 6,079 | Form 4 |
| 2026-09-08 | Wang XiaodongDirector, Other | Saleplan | 2,841 | 346.16 | $983,441 | 3,238 | Form 4 |
| 2026-09-08 | Wang XiaodongDirector, Other | Saleplan | 1,517 | 347.39 | $526,991 | 1,721 | Form 4 |
| 2026-09-08 | Wang XiaodongDirector, Other | Saleplan | 1,721 | 348.01 | $598,925 | 0 | Form 4 |
| 2026-09-08 | Wang XiaodongDirector, Other | Saleplan | 7,492 | 348.31 | $2.61M | 23,535 | Form 4 |
| 2026-09-08 | Wang XiaodongDirector, Other | Saleplan | 10,688 | 349.28 | $3.73M | 12,847 | Form 4 |
| 2026-09-08 | Wang XiaodongDirector, Other | Saleplan | 6,569 | 350.27 | $2.30M | 6,278 | Form 4 |
| 2026-09-08 | Wang XiaodongDirector, Other | Saleplan | 6,278 | 351.25 | $2.21M | 0 | Form 4 |
| 2026-09-01 | Ball Titus B.Principal Accounting Officer | Sale | 132 | 355.86 | $46,974 | 0 | Form 4 |
| 2026-08-25 | Wu XiaobinPresident and COO | Saleplan | 280 | 380.00 | $106,400 | 0 | Form 4 |
| 2026-08-12 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 1,980 | 354.71 | $702,326 | 52,912 | Form 4 |
| 2026-08-12 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 2,515 | 356.43 | $896,421 | 50,397 | Form 4 |
| 2026-08-12 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 15,396 | 357.63 | $5.51M | 35,001 | Form 4 |
| 2026-08-12 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 20,899 | 358.41 | $7.49M | 14,102 | Form 4 |
| 2026-08-12 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 14,102 | 359.12 | $5.06M | 0 | Form 4 |
| 2026-08-11 | Lee Chan HenrySVP, General Counsel | Saleplan | 2,666 | 360.00 | $959,760 | 0 | Form 4 |
| 2026-08-11 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 13,695 | 359.32 | $4.92M | 112,104 | Form 4 |
| 2026-08-11 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 8,081 | 360.33 | $2.91M | 104,023 | Form 4 |
| 2026-08-11 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 14,569 | 361.47 | $5.27M | 89,454 | Form 4 |
| 2026-08-11 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 11,568 | 362.34 | $4.19M | 77,886 | Form 4 |
| 2026-08-11 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 13,403 | 363.45 | $4.87M | 64,483 | Form 4 |
| 2026-08-11 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 5,211 | 364.31 | $1.90M | 59,272 | Form 4 |
| 2026-08-11 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 3,176 | 365.26 | $1.16M | 56,096 | Form 4 |
| 2026-08-11 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 1,200 | 366.31 | $439,572 | 54,896 | Form 4 |
| 2026-08-11 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 4 | 367.00 | $1,468 | 54,892 | Form 4 |
| 2026-08-10 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 67 | 350.00 | $23,450 | 240,743 | Form 4 |
| 2026-08-10 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 2,813 | 351.80 | $989,613 | 237,930 | Form 4 |
| 2026-08-10 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 3,673 | 353.32 | $1.30M | 234,257 | Form 4 |
| 2026-08-10 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 6,717 | 354.78 | $2.38M | 227,540 | Form 4 |
388 more
| 2026-08-10 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 3,476 | 355.66 | $1.24M | 224,064 | Form 4 |
| 2026-08-10 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 12,418 | 356.62 | $4.43M | 211,646 | Form 4 |
| 2026-08-10 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 15,869 | 357.67 | $5.68M | 195,777 | Form 4 |
| 2026-08-10 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 45,044 | 358.70 | $16.16M | 150,733 | Form 4 |
| 2026-08-10 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 21,254 | 359.50 | $7.64M | 129,479 | Form 4 |
| 2026-08-10 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 3,680 | 360.63 | $1.33M | 125,799 | Form 4 |
| 2026-08-03 | Rosenberg AaronChief Financial Officer | Sale | 1,157 | 312.72 | $361,817 | 0 | Form 4 |
| 2026-07-30 | Lee Chan HenrySVP, General Counsel | Sale | 1,044 | 323.69 | $337,932 | 0 | Form 4 |
| 2026-07-22 | Lee Chan HenrySVP, General Counsel | Saleplan | 1,669 | 325.00 | $542,425 | 0 | Form 4 |
| 2026-07-21 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 15,379 | 316.26 | $4.86M | 46,018 | Form 4 |
| 2026-07-21 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 20,029 | 316.91 | $6.35M | 25,989 | Form 4 |
| 2026-07-21 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 7,842 | 318.41 | $2.50M | 18,147 | Form 4 |
| 2026-07-21 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 15,807 | 319.29 | $5.05M | 2,340 | Form 4 |
| 2026-07-21 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 2,340 | 320.06 | $748,940 | 0 | Form 4 |
| 2026-07-20 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 5,146 | 310.08 | $1.60M | 9,180 | Form 4 |
| 2026-07-20 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 6,273 | 310.75 | $1.95M | 2,907 | Form 4 |
| 2026-07-20 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 2,907 | 311.80 | $906,403 | 0 | Form 4 |
| 2026-07-20 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 15,499 | 312.29 | $4.84M | 18,491 | Form 4 |
| 2026-07-20 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 14,326 | 312.96 | $4.48M | 4,165 | Form 4 |
| 2026-07-20 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 1,850 | 313.91 | $580,734 | 2,315 | Form 4 |
| 2026-07-20 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 1,512 | 315.26 | $476,673 | 803 | Form 4 |
| 2026-07-20 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 523 | 316.14 | $165,341 | 280 | Form 4 |
| 2026-07-20 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 280 | 318.30 | $89,124 | 0 | Form 4 |
| 2026-07-17 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 1,440 | 305.20 | $439,488 | 63,188 | Form 4 |
| 2026-07-17 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 597 | 306.96 | $183,255 | 62,591 | Form 4 |
| 2026-07-17 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 680 | 309.05 | $210,154 | 61,911 | Form 4 |
| 2026-07-17 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 4,833 | 310.37 | $1.50M | 57,078 | Form 4 |
| 2026-07-17 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 5,543 | 311.42 | $1.73M | 51,535 | Form 4 |
| 2026-07-17 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 35,829 | 312.17 | $11.18M | 15,706 | Form 4 |
| 2026-07-17 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 14,915 | 313.19 | $4.67M | 791 | Form 4 |
| 2026-07-17 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 740 | 314.32 | $232,597 | 51 | Form 4 |
| 2026-07-17 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 51 | 315.06 | $16,068 | 0 | Form 4 |
| 2026-07-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 233 | 311.98 | $72,691 | 166,364 | Form 4 |
| 2026-07-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 4,881 | 314.08 | $1.53M | 161,483 | Form 4 |
| 2026-07-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 9,516 | 314.73 | $2.99M | 151,967 | Form 4 |
| 2026-07-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 19,752 | 316.00 | $6.24M | 132,215 | Form 4 |
| 2026-07-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 32,224 | 316.82 | $10.21M | 99,991 | Form 4 |
| 2026-07-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 42,798 | 317.79 | $13.60M | 57,193 | Form 4 |
| 2026-07-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 6,402 | 318.55 | $2.04M | 50,791 | Form 4 |
| 2026-07-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 15,097 | 319.99 | $4.83M | 35,694 | Form 4 |
| 2026-07-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 20,505 | 321.00 | $6.58M | 15,189 | Form 4 |
| 2026-07-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 13,109 | 321.61 | $4.22M | 2,080 | Form 4 |
| 2026-07-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 1,560 | 322.71 | $503,428 | 520 | Form 4 |
| 2026-07-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 520 | 323.59 | $168,267 | 0 | Form 4 |
| 2026-07-15 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 6,067 | 310.02 | $1.88M | 110,490 | Form 4 |
| 2026-07-15 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 41,336 | 310.92 | $12.85M | 69,154 | Form 4 |
| 2026-07-15 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 12,857 | 311.71 | $4.01M | 56,297 | Form 4 |
| 2026-07-15 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 48,657 | 312.86 | $15.22M | 7,640 | Form 4 |
| 2026-07-15 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 7,640 | 313.58 | $2.40M | 0 | Form 4 |
| 2026-07-14 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 4,139 | 303.07 | $1.25M | 8,122 | Form 4 |
| 2026-07-14 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 8,122 | 303.93 | $2.47M | 0 | Form 4 |
| 2026-07-14 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 39,090 | 305.02 | $11.92M | 94,510 | Form 4 |
| 2026-07-14 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 45,895 | 306.21 | $14.05M | 48,615 | Form 4 |
| 2026-07-14 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 40,781 | 306.93 | $12.52M | 7,834 | Form 4 |
| 2026-07-14 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 7,834 | 307.57 | $2.41M | 0 | Form 4 |
| 2026-07-13 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 798 | 301.94 | $240,948 | 47,722 | Form 4 |
| 2026-07-13 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 4,584 | 302.79 | $1.39M | 43,138 | Form 4 |
| 2026-07-13 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 26,294 | 303.83 | $7.99M | 16,844 | Form 4 |
| 2026-07-13 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 8,438 | 304.68 | $2.57M | 8,406 | Form 4 |
| 2026-07-13 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 846 | 305.57 | $258,512 | 7,560 | Form 4 |
| 2026-07-13 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 7,240 | 306.82 | $2.22M | 320 | Form 4 |
| 2026-07-13 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 320 | 307.41 | $98,371 | 0 | Form 4 |
| 2026-07-10 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 1,493 | 296.07 | $442,033 | 10,205 | Form 4 |
| 2026-07-10 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 1,314 | 297.23 | $390,560 | 8,891 | Form 4 |
| 2026-07-10 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 3,074 | 298.35 | $917,128 | 5,817 | Form 4 |
| 2026-07-10 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 5,143 | 298.94 | $1.54M | 674 | Form 4 |
| 2026-07-10 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 370 | 300.12 | $111,044 | 304 | Form 4 |
| 2026-07-10 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 150 | 301.18 | $45,177 | 154 | Form 4 |
| 2026-07-10 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 136 | 302.19 | $41,098 | 18 | Form 4 |
| 2026-07-10 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 18 | 303.03 | $5,455 | 0 | Form 4 |
| 2026-07-08 | Lee Chan HenrySVP, General Counsel | Saleplan | 664 | 302.46 | $200,833 | 0 | Form 4 |
| 2026-06-23 | Oyler JohnDirector, Chief Executive Officer | Sale | 1,800 | 273.30 | $491,940 | 1,610 | Form 4 |
| 2026-06-23 | Oyler JohnDirector, Chief Executive Officer | Sale | 1,290 | 274.12 | $353,615 | 320 | Form 4 |
| 2026-06-23 | Oyler JohnDirector, Chief Executive Officer | Sale | 320 | 275.10 | $88,032 | 0 | Form 4 |
| 2026-06-23 | Wu XiaobinPresident and COO | Sale | 1,292 | 276.26 | $356,928 | 0 | Form 4 |
| 2026-06-23 | Wang LaiPresident, Global Head of R&D | Sale | 1,068 | 276.74 | $295,558 | 0 | Form 4 |
| 2026-06-16 | Oyler JohnDirector, Chief Executive Officer | Sale | 1,650 | 264.87 | $437,036 | 2,043 | Form 4 |
| 2026-06-16 | Oyler JohnDirector, Chief Executive Officer | Sale | 1,710 | 265.99 | $454,843 | 333 | Form 4 |
| 2026-06-16 | Oyler JohnDirector, Chief Executive Officer | Sale | 333 | 266.69 | $88,808 | 0 | Form 4 |
| 2026-06-16 | Wu XiaobinPresident and COO | Sale | 1,357 | 266.76 | $361,993 | 0 | Form 4 |
| 2026-06-16 | Wang LaiPresident, Global Head of R&D | Sale | 1,169 | 265.39 | $310,241 | 0 | Form 4 |
| 2026-06-16 | Lee Chan HenrySVP, General Counsel | Sale | 590 | 265.98 | $156,928 | 0 | Form 4 |
| 2026-06-11 | Oyler JohnDirector, Chief Executive Officer | Sale | 741 | 256.23 | $189,866 | 1,208 | Form 4 |
| 2026-06-11 | Oyler JohnDirector, Chief Executive Officer | Sale | 859 | 257.59 | $221,270 | 349 | Form 4 |
| 2026-06-11 | Oyler JohnDirector, Chief Executive Officer | Sale | 200 | 258.28 | $51,656 | 149 | Form 4 |
| 2026-06-11 | Oyler JohnDirector, Chief Executive Officer | Sale | 149 | 258.81 | $38,563 | 0 | Form 4 |
| 2026-06-11 | Ball Titus B.Principal Accounting Officer | Sale | 49 | 256.39 | $12,563 | 120 | Form 4 |
| 2026-06-11 | Ball Titus B.Principal Accounting Officer | Sale | 120 | 257.53 | $30,904 | 0 | Form 4 |
| 2026-06-11 | Wu XiaobinPresident and COO | Sale | 626 | 261.20 | $163,511 | 0 | Form 4 |
| 2026-06-11 | Wang LaiPresident, Global Head of R&D | Sale | 756 | 261.00 | $197,316 | 0 | Form 4 |
| 2026-06-11 | Lee Chan HenrySVP, General Counsel | Sale | 428 | 257.64 | $110,270 | 0 | Form 4 |
| 2026-06-11 | Rosenberg AaronChief Financial Officer | Sale | 631 | 257.74 | $162,634 | 0 | Form 4 |
| 2026-06-08 | Oyler JohnDirector, Chief Executive Officer | Sale | 3,820 | 270.38 | $1.03M | 1,120 | Form 4 |
| 2026-06-08 | Oyler JohnDirector, Chief Executive Officer | Sale | 1,120 | 271.14 | $303,677 | 0 | Form 4 |
| 2026-06-08 | Ball Titus B.Principal Accounting Officer | Sale | 100 | 271.06 | $27,106 | 36 | Form 4 |
| 2026-06-08 | Ball Titus B.Principal Accounting Officer | Sale | 36 | 272.08 | $9,795 | 0 | Form 4 |
| 2026-06-08 | Wu XiaobinPresident and COO | Sale | 1,444 | 269.33 | $388,913 | 40 | Form 4 |
| 2026-06-08 | Wu XiaobinPresident and COO | Sale | 40 | 270.55 | $10,822 | 0 | Form 4 |
| 2026-06-08 | Wang LaiPresident, Global Head of R&D | Sale | 1,327 | 269.34 | $357,414 | 40 | Form 4 |
| 2026-06-08 | Wang LaiPresident, Global Head of R&D | Sale | 40 | 270.73 | $10,829 | 0 | Form 4 |
| 2026-06-08 | Lee Chan HenrySVP, General Counsel | Sale | 711 | 270.24 | $192,141 | 160 | Form 4 |
| 2026-06-08 | Lee Chan HenrySVP, General Counsel | Sale | 160 | 271.26 | $43,402 | 0 | Form 4 |
| 2026-06-01 | Yi QingqingDirector | Sale | 235 | 279.13 | $65,596 | 0 | Form 4 |
| 2026-05-22 | Baker JulianDirectorwith Baker Felix, Baker Bros. Advisors LP, Baker Brothers Life Sciences LP, 667, L.P., Baker Bros. Advisors (gp) LLC | Saleindirect | 2,743 | 23.85 | $65,421 | 145,322 | Form 4 |
| 2026-05-22 | Baker JulianDirectorwith Baker Felix, Baker Bros. Advisors LP, Baker Brothers Life Sciences LP, 667, L.P., Baker Bros. Advisors (gp) LLC | Saleindirect | 2,743 | 23.85 | $65,421 | 145,326 | Form 4 |
| 2026-05-22 | Baker JulianDirectorwith Baker Felix, Baker Bros. Advisors LP, Baker Brothers Life Sciences LP, 667, L.P., Baker Bros. Advisors (gp) LLC | Saleindirect | 2,756 | 23.79 | $65,565 | 142,566 | Form 4 |
| 2026-05-22 | Baker JulianDirectorwith Baker Felix, Baker Bros. Advisors LP, Baker Brothers Life Sciences LP, 667, L.P., Baker Bros. Advisors (gp) LLC | Saleindirect | 2,756 | 23.79 | $65,565 | 142,570 | Form 4 |
| 2026-05-22 | Sanders Corazon (Corsee) D.Director | Sale | 212 | 309.59 | $65,633 | 0 | Form 4 |
| 2026-05-22 | Riva AlessandroDirector | Sale | 212 | 309.51 | $65,616 | 0 | Form 4 |
| 2026-05-22 | Dugan MargaretDirector | Sale | 212 | 309.60 | $65,635 | 0 | Form 4 |
| 2026-05-13 | Lee Chan HenrySVP, General Counsel | Saleplan | 332 | 310.72 | $103,159 | 0 | Form 4 |
| 2026-04-08 | Lee Chan HenrySVP, General Counsel | Saleplan | 332 | 311.59 | $103,448 | 0 | Form 4 |
| 2026-03-11 | Lee Chan HenrySVP, General Counsel | Saleplan | 341 | 300.00 | $102,300 | 0 | Form 4 |
| 2026-02-04 | Lee Chan HenrySVP, General Counsel | Saleplan | 664 | 348.79 | $231,597 | 996 | Form 4 |
| 2026-02-04 | Lee Chan HenrySVP, General Counsel | Saleplan | 996 | 350.00 | $348,600 | 0 | Form 4 |
| 2026-01-07 | Lee Chan HenrySVP, General Counsel | Saleplan | 664 | 331.76 | $220,289 | 0 | Form 4 |
| 2025-12-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 1,877 | 300.80 | $564,602 | 22,492 | Form 4 |
| 2025-12-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 600 | 300.98 | $180,588 | 21,892 | Form 4 |
| 2025-12-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 2,567 | 301.79 | $774,695 | 19,325 | Form 4 |
| 2025-12-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 1,512 | 302.31 | $457,093 | 17,813 | Form 4 |
| 2025-12-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 7,470 | 302.74 | $2.26M | 10,343 | Form 4 |
| 2025-12-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 1,633 | 303.13 | $495,011 | 8,710 | Form 4 |
| 2025-12-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 5,442 | 303.72 | $1.65M | 3,268 | Form 4 |
| 2025-12-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 1,255 | 304.13 | $381,683 | 2,013 | Form 4 |
| 2025-12-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 1,973 | 304.36 | $600,502 | 40 | Form 4 |
| 2025-12-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 40 | 305.24 | $12,210 | 0 | Form 4 |
| 2025-12-15 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 1,791 | 301.58 | $540,130 | 98,209 | Form 4 |
| 2025-12-15 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 6,389 | 302.29 | $1.93M | 91,820 | Form 4 |
| 2025-12-15 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 1,896 | 303.60 | $575,626 | 89,924 | Form 4 |
| 2025-12-15 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 5,829 | 304.37 | $1.77M | 84,095 | Form 4 |
| 2025-12-15 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 3,940 | 305.55 | $1.20M | 80,155 | Form 4 |
| 2025-12-15 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 4,949 | 306.39 | $1.52M | 75,206 | Form 4 |
| 2025-12-15 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 5,118 | 307.38 | $1.57M | 70,088 | Form 4 |
| 2025-12-15 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 14,163 | 308.41 | $4.37M | 55,925 | Form 4 |
| 2025-12-15 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 10,650 | 309.37 | $3.29M | 45,275 | Form 4 |
| 2025-12-15 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 16,318 | 310.48 | $5.07M | 28,957 | Form 4 |
| 2025-12-15 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 2,344 | 311.33 | $729,758 | 26,613 | Form 4 |
| 2025-12-15 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 121 | 311.93 | $37,744 | 26,492 | Form 4 |
| 2025-12-15 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 929 | 313.52 | $291,260 | 25,563 | Form 4 |
| 2025-12-15 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 1,194 | 314.92 | $376,014 | 24,369 | Form 4 |
| 2025-12-11 | Lee Chan HenrySVP, General Counsel | Saleplan | 332 | 325.00 | $107,900 | 0 | Form 4 |
| 2025-12-10 | Lee Chan HenrySVP, General Counsel | Saleplan | 332 | 318.28 | $105,669 | 0 | Form 4 |
| 2025-11-26 | Sanders Corazon (Corsee) D.Director | Sale | 1,823 | 340.20 | $620,185 | 804 | Form 4 |
| 2025-11-26 | Sanders Corazon (Corsee) D.Director | Sale | 804 | 342.47 | $275,346 | 0 | Form 4 |
| 2025-11-17 | Wu XiaobinPresident and COO | Sale | 3,155 | 380.23 | $1.20M | 836 | Form 4 |
| 2025-11-17 | Wu XiaobinPresident and COO | Sale | 826 | 381.19 | $314,863 | 10 | Form 4 |
| 2025-11-17 | Wu XiaobinPresident and COO | Sale | 10 | 382.32 | $3,823 | 0 | Form 4 |
| 2025-11-13 | Wu XiaobinPresident and COO | Sale | 4,240 | 380.33 | $1.61M | 1,769 | Form 4 |
| 2025-11-13 | Wu XiaobinPresident and COO | Sale | 1,769 | 381.05 | $674,077 | 0 | Form 4 |
| 2025-11-12 | Wu XiaobinPresident and COO | Sale | 500 | 350.44 | $175,220 | 15,509 | Form 4 |
| 2025-11-12 | Wu XiaobinPresident and COO | Sale | 3,240 | 351.41 | $1.14M | 12,269 | Form 4 |
| 2025-11-12 | Wu XiaobinPresident and COO | Sale | 789 | 352.78 | $278,343 | 11,480 | Form 4 |
| 2025-11-12 | Wu XiaobinPresident and COO | Sale | 251 | 354.20 | $88,904 | 11,229 | Form 4 |
| 2025-11-12 | Wu XiaobinPresident and COO | Sale | 120 | 355.00 | $42,600 | 11,109 | Form 4 |
| 2025-11-12 | Wu XiaobinPresident and COO | Sale | 100 | 357.43 | $35,743 | 11,009 | Form 4 |
| 2025-11-12 | Wu XiaobinPresident and COO | Sale | 4,846 | 360.10 | $1.75M | 6,163 | Form 4 |
| 2025-11-12 | Wu XiaobinPresident and COO | Sale | 154 | 362.07 | $55,759 | 6,009 | Form 4 |
| 2025-11-12 | Lee Chan HenrySVP, General Counsel | Saleplan | 664 | 348.75 | $231,570 | 332 | Form 4 |
| 2025-11-12 | Lee Chan HenrySVP, General Counsel | Saleplan | 332 | 350.00 | $116,200 | 0 | Form 4 |
| 2025-10-08 | Lee Chan HenrySVP, General Counsel | Saleplan | 1,112 | 350.00 | $389,200 | 0 | Form 4 |
| 2025-10-08 | Lee Chan HenrySVP, General Counsel | Saleplan | 664 | 347.82 | $230,952 | 8,895 | Form 4 |
| 2025-10-08 | Lee Chan HenrySVP, General Counsel | Saleplan | 4,733 | 350.22 | $1.66M | 4,162 | Form 4 |
| 2025-10-08 | Lee Chan HenrySVP, General Counsel | Saleplan | 4,162 | 351.12 | $1.46M | 0 | Form 4 |
| 2025-09-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 4,066 | 324.12 | $1.32M | 23,737 | Form 4 |
| 2025-09-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 6,883 | 325.06 | $2.24M | 16,854 | Form 4 |
| 2025-09-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 12,446 | 326.14 | $4.06M | 4,408 | Form 4 |
| 2025-09-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 4,008 | 326.90 | $1.31M | 400 | Form 4 |
| 2025-09-16 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 400 | 327.78 | $131,112 | 0 | Form 4 |
| 2025-09-10 | Lee Chan HenrySVP, General Counsel | Saleplan | 1,112 | 325.00 | $361,400 | 0 | Form 4 |
| 2025-09-10 | Lee Chan HenrySVP, General Counsel | Saleplan | 4,776 | 325.19 | $1.55M | 4,118 | Form 4 |
| 2025-09-10 | Lee Chan HenrySVP, General Counsel | Saleplan | 3,318 | 325.73 | $1.08M | 800 | Form 4 |
| 2025-09-10 | Lee Chan HenrySVP, General Counsel | Saleplan | 300 | 326.80 | $98,040 | 500 | Form 4 |
| 2025-09-10 | Lee Chan HenrySVP, General Counsel | Saleplan | 500 | 327.93 | $163,965 | 0 | Form 4 |
| 2025-09-09 | Wang LaiGlobal Head of R&D | Saleplanindirect | 5,000 | 350.06 | $1.75M | 0 | Form 4 |
| 2025-09-05 | Sanders Corazon (Corsee) D.Director | Sale | 2,665 | 337.00 | $898,105 | 0 | Form 4 |
| 2025-09-02 | Ball Titus B.Principal Accounting Officer | Sale | 122 | 326.76 | $39,865 | 0 | Form 4 |
| 2025-08-14 | Wu XiaobinPresident and COO | Saleplan | 400 | 300.86 | $120,344 | 39,536 | Form 4 |
| 2025-08-14 | Wu XiaobinPresident and COO | Saleplan | 5,800 | 302.04 | $1.75M | 33,736 | Form 4 |
| 2025-08-14 | Wu XiaobinPresident and COO | Saleplan | 6,965 | 303.31 | $2.11M | 26,771 | Form 4 |
| 2025-08-14 | Wu XiaobinPresident and COO | Saleplan | 500 | 304.19 | $152,095 | 26,271 | Form 4 |
| 2025-08-14 | Wu XiaobinPresident and COO | Saleplan | 8,522 | 305.48 | $2.60M | 17,749 | Form 4 |
| 2025-08-14 | Wu XiaobinPresident and COO | Saleplan | 12,232 | 306.26 | $3.75M | 5,517 | Form 4 |
| 2025-08-14 | Wu XiaobinPresident and COO | Saleplan | 4,917 | 307.43 | $1.51M | 600 | Form 4 |
| 2025-08-14 | Wu XiaobinPresident and COO | Saleplan | 600 | 308.03 | $184,818 | 0 | Form 4 |
| 2025-08-13 | Lee Chan HenrySVP, General Counsel | Saleplan | 1,112 | 300.00 | $333,600 | 0 | Form 4 |
| 2025-08-13 | Lee Chan HenrySVP, General Counsel | Saleplan | 6,052 | 300.19 | $1.82M | 2,178 | Form 4 |
| 2025-08-13 | Lee Chan HenrySVP, General Counsel | Saleplan | 3,849 | 301.00 | $1.16M | 0 | Form 4 |
| 2025-08-13 | Wu XiaobinPresident and COO | Saleplan | 8,900 | 300.33 | $2.67M | 40,958 | Form 4 |
| 2025-08-13 | Wu XiaobinPresident and COO | Saleplan | 4,500 | 301.49 | $1.36M | 36,458 | Form 4 |
| 2025-08-13 | Wu XiaobinPresident and COO | Saleplan | 5,800 | 302.45 | $1.75M | 30,658 | Form 4 |
| 2025-08-13 | Wu XiaobinPresident and COO | Saleplan | 3,517 | 303.54 | $1.07M | 27,141 | Form 4 |
| 2025-08-13 | Wu XiaobinPresident and COO | Saleplan | 7,359 | 304.37 | $2.24M | 19,782 | Form 4 |
| 2025-08-13 | Wu XiaobinPresident and COO | Saleplan | 528 | 305.59 | $161,352 | 19,254 | Form 4 |
| 2025-08-13 | Wu XiaobinPresident and COO | Saleplan | 9,637 | 306.74 | $2.96M | 9,617 | Form 4 |
| 2025-08-13 | Wu XiaobinPresident and COO | Saleplan | 9,617 | 307.38 | $2.96M | 0 | Form 4 |
| 2025-08-01 | Rosenberg AaronChief Financial Officer | Sale | 1,190 | 290.47 | $345,659 | 0 | Form 4 |
| 2025-07-30 | Lee Chan HenrySVP, General Counsel | Sale | 920 | 304.60 | $280,232 | 0 | Form 4 |
| 2025-07-30 | Wang LaiGlobal Head of R&D | Saleplanindirect | 259 | 305.00 | $78,995 | 0 | Form 4 |
| 2025-07-29 | Wang LaiGlobal Head of R&D | Saleplanindirect | 2,949 | 302.00 | $890,598 | 1,351 | Form 4 |
| 2025-07-29 | Wang LaiGlobal Head of R&D | Saleplanindirect | 292 | 302.92 | $88,453 | 1,059 | Form 4 |
| 2025-07-29 | Wang LaiGlobal Head of R&D | Saleplanindirect | 800 | 304.16 | $243,328 | 259 | Form 4 |
| 2025-07-18 | Wang LaiGlobal Head of R&D | Saleplanindirect | 700 | 300.00 | $210,000 | 0 | Form 4 |
| 2025-07-09 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 6,703 | 252.23 | $1.69M | 21,099 | Form 4 |
| 2025-07-09 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 9,292 | 253.18 | $2.35M | 11,807 | Form 4 |
| 2025-07-09 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 10,254 | 254.10 | $2.61M | 1,553 | Form 4 |
| 2025-07-09 | Oyler JohnDirector, Chief Executive Officer | Saleplan | 1,553 | 254.83 | $395,751 | 0 | Form 4 |
| 2025-06-24 | Wang XiaodongDirector, Other | Saleplan | 300 | 263.50 | $79,050 | 1,707 | Form 4 |
| 2025-06-24 | Wang XiaodongDirector, Other | Saleplan | 1,100 | 265.35 | $291,885 | 607 | Form 4 |
| 2025-06-24 | Wang XiaodongDirector, Other | Saleplan | 507 | 266.57 | $135,151 | 100 | Form 4 |
| 2025-06-24 | Wang XiaodongDirector, Other | Saleplan | 100 | 267.81 | $26,781 | 0 | Form 4 |
| 2025-06-23 | Oyler JohnDirector, Chief Executive Officer | Sale | 3,074 | 261.57 | $804,066 | 100 | Form 4 |
| 2025-06-23 | Oyler JohnDirector, Chief Executive Officer | Sale | 100 | 262.90 | $26,290 | 0 | Form 4 |
| 2025-06-23 | Wu XiaobinPresident and COO | Sale | 1,363 | 260.00 | $354,380 | 0 | Form 4 |
| 2025-06-23 | Wang LaiGlobal Head of R&D | Sale | 1,028 | 260.00 | $267,280 | 0 | Form 4 |
| 2025-06-17 | Oyler JohnDirector, Chief Executive Officer | Sale | 1,460 | 256.49 | $374,475 | 0 | Form 4 |
| 2025-06-17 | Wu XiaobinPresident and COO | Sale | 630 | 250.87 | $158,048 | 0 | Form 4 |
| 2025-06-17 | Wang LaiGlobal Head of R&D | Sale | 470 | 251.37 | $118,144 | 0 | Form 4 |
| 2025-06-16 | Oyler JohnDirector, Chief Executive Officer | Sale | 3,680 | 266.05 | $979,064 | 1,460 | Form 4 |
| 2025-06-16 | Wu XiaobinPresident and COO | Sale | 1,443 | 265.47 | $383,073 | 730 | Form 4 |
| 2025-06-16 | Wu XiaobinPresident and COO | Sale | 100 | 266.22 | $26,622 | 630 | Form 4 |
| 2025-06-16 | Wang LaiGlobal Head of R&D | Sale | 1,177 | 266.40 | $313,553 | 470 | Form 4 |
| 2025-06-16 | Lee Chan HenrySVP, General Counsel | Sale | 422 | 266.50 | $112,463 | 0 | Form 4 |
| 2025-06-11 | Ball Titus B.Principal Accounting Officer | Sale | 134 | 258.36 | $34,620 | 0 | Form 4 |
| 2025-06-10 | Wang XiaodongDirector, Other | Saleplan | 2,901 | 261.20 | $757,741 | 38,859 | Form 4 |
| 2025-06-10 | Wang XiaodongDirector, Other | Saleplan | 15,878 | 262.20 | $4.16M | 22,981 | Form 4 |
| 2025-06-10 | Wang XiaodongDirector, Other | Saleplan | 16,094 | 263.17 | $4.24M | 6,887 | Form 4 |
| 2025-06-10 | Wang XiaodongDirector, Other | Saleplan | 6,787 | 264.08 | $1.79M | 100 | Form 4 |
| 2025-06-10 | Wang XiaodongDirector, Other | Saleplan | 100 | 264.85 | $26,485 | 0 | Form 4 |
| 2025-06-06 | Oyler JohnDirector, Chief Executive Officer | Sale | 1,400 | 250.84 | $351,176 | 3,727 | Form 4 |
| 2025-06-06 | Oyler JohnDirector, Chief Executive Officer | Sale | 1,400 | 251.88 | $352,632 | 2,327 | Form 4 |
| 2025-06-06 | Oyler JohnDirector, Chief Executive Officer | Sale | 1,000 | 253.49 | $253,490 | 1,327 | Form 4 |
| 2025-06-06 | Oyler JohnDirector, Chief Executive Officer | Sale | 927 | 254.97 | $236,357 | 400 | Form 4 |
| 2025-06-06 | Oyler JohnDirector, Chief Executive Officer | Sale | 400 | 255.74 | $102,296 | 0 | Form 4 |
| 2025-06-06 | Wu XiaobinPresident and COO | Sale | 400 | 250.74 | $100,296 | 1,534 | Form 4 |
| 2025-06-06 | Wu XiaobinPresident and COO | Sale | 500 | 251.85 | $125,925 | 1,034 | Form 4 |
| 2025-06-06 | Wu XiaobinPresident and COO | Sale | 400 | 253.50 | $101,400 | 634 | Form 4 |
| 2025-06-06 | Wu XiaobinPresident and COO | Sale | 400 | 255.31 | $102,124 | 234 | Form 4 |
| 2025-06-06 | Wu XiaobinPresident and COO | Sale | 234 | 255.77 | $59,850 | 0 | Form 4 |
| 2025-06-06 | Wang LaiGlobal Head of R&D | Sale | 600 | 250.71 | $150,426 | 802 | Form 4 |
| 2025-06-06 | Wang LaiGlobal Head of R&D | Sale | 202 | 251.89 | $50,882 | 600 | Form 4 |
| 2025-06-06 | Wang LaiGlobal Head of R&D | Sale | 300 | 253.19 | $75,957 | 300 | Form 4 |
| 2025-06-06 | Wang LaiGlobal Head of R&D | Sale | 300 | 255.30 | $76,590 | 0 | Form 4 |
| 2025-06-06 | Lee Chan HenrySVP, General Counsel | Sale | 470 | 255.78 | $120,217 | 230 | Form 4 |
| 2025-06-06 | Lee Chan HenrySVP, General Counsel | Sale | 230 | 256.79 | $59,062 | 0 | Form 4 |
| 2025-05-13 | Wang XiaodongDirector, Other | Saleplan | 10,221 | 222.83 | $2.28M | 31,539 | Form 4 |
| 2025-05-13 | Wang XiaodongDirector, Other | Saleplan | 21,235 | 223.41 | $4.74M | 10,304 | Form 4 |
| 2025-05-13 | Wang XiaodongDirector, Other | Saleplan | 10,104 | 224.32 | $2.27M | 200 | Form 4 |
| 2025-05-13 | Wang XiaodongDirector, Other | Saleplan | 200 | 225.68 | $45,136 | 0 | Form 4 |
| 2025-04-14 | Wang XiaodongDirector, Other | Saleplan | 995 | 237.56 | $236,372 | 40,765 | Form 4 |
| 2025-04-14 | Wang XiaodongDirector, Other | Saleplan | 805 | 238.48 | $191,976 | 39,960 | Form 4 |
| 2025-04-14 | Wang XiaodongDirector, Other | Saleplan | 2,884 | 239.51 | $690,747 | 37,076 | Form 4 |
| 2025-04-14 | Wang XiaodongDirector, Other | Saleplan | 5,516 | 240.41 | $1.33M | 31,560 | Form 4 |
| 2025-04-14 | Wang XiaodongDirector, Other | Saleplan | 2,229 | 241.51 | $538,326 | 29,331 | Form 4 |
| 2025-04-14 | Wang XiaodongDirector, Other | Saleplan | 15,041 | 242.59 | $3.65M | 14,290 | Form 4 |
| 2025-04-14 | Wang XiaodongDirector, Other | Saleplan | 6,398 | 243.41 | $1.56M | 7,892 | Form 4 |
| 2025-04-14 | Wang XiaodongDirector, Other | Saleplan | 1,592 | 244.56 | $389,340 | 6,300 | Form 4 |
| 2025-04-14 | Wang XiaodongDirector, Other | Saleplan | 2,056 | 245.56 | $504,871 | 4,244 | Form 4 |
| 2025-04-14 | Wang XiaodongDirector, Other | Saleplan | 1,869 | 246.40 | $460,522 | 2,375 | Form 4 |
| 2025-04-14 | Wang XiaodongDirector, Other | Saleplan | 1,475 | 247.46 | $365,004 | 900 | Form 4 |
| 2025-04-14 | Wang XiaodongDirector, Other | Saleplan | 535 | 248.90 | $133,162 | 365 | Form 4 |
| 2025-04-14 | Wang XiaodongDirector, Other | Saleplan | 365 | 249.45 | $91,049 | 0 | Form 4 |
| 2025-04-01 | Wu XiaobinPresident, COO & GM China | Saleplan | 28,253 | 280.31 | $7.92M | 23,668 | Form 4 |
| 2025-04-01 | Wu XiaobinPresident, COO & GM China | Saleplan | 6,364 | 281.67 | $1.79M | 17,304 | Form 4 |
| 2025-04-01 | Wu XiaobinPresident, COO & GM China | Saleplan | 12,221 | 282.76 | $3.46M | 5,083 | Form 4 |
| 2025-04-01 | Wu XiaobinPresident, COO & GM China | Saleplan | 5,083 | 283.79 | $1.44M | 0 | Form 4 |
| 2025-03-18 | Wang XiaodongDirector, Other | Saleplan | 2,417 | 258.25 | $624,190 | 39,343 | Form 4 |
| 2025-03-18 | Wang XiaodongDirector, Other | Saleplan | 6,926 | 259.08 | $1.79M | 32,417 | Form 4 |
| 2025-03-18 | Wang XiaodongDirector, Other | Saleplan | 2,694 | 259.86 | $700,063 | 29,723 | Form 4 |
| 2025-03-18 | Wang XiaodongDirector, Other | Saleplan | 10,448 | 261.44 | $2.73M | 19,275 | Form 4 |
| 2025-03-18 | Wang XiaodongDirector, Other | Saleplan | 11,245 | 262.12 | $2.95M | 8,030 | Form 4 |
| 2025-03-18 | Wang XiaodongDirector, Other | Saleplan | 6,923 | 263.08 | $1.82M | 1,107 | Form 4 |
| 2025-03-18 | Wang XiaodongDirector, Other | Saleplan | 1,107 | 264.01 | $292,259 | 0 | Form 4 |
| 2025-03-14 | Wu XiaobinPresident, COO & GM China | Saleindirect | 0 | – | – | 0 | Form 4 |
| 2025-03-10 | Oyler JohnDirector, Chief Executive Officer | Sale | 1,900 | 238.74 | $453,606 | 39,310 | Form 4 |
| 2025-03-10 | Oyler JohnDirector, Chief Executive Officer | Sale | 6,800 | 239.59 | $1.63M | 32,510 | Form 4 |
| 2025-03-10 | Oyler JohnDirector, Chief Executive Officer | Sale | 2,200 | 240.70 | $529,540 | 30,310 | Form 4 |
| 2025-03-10 | Oyler JohnDirector, Chief Executive Officer | Sale | 7,069 | 241.92 | $1.71M | 23,241 | Form 4 |
| 2025-03-10 | Oyler JohnDirector, Chief Executive Officer | Sale | 9,309 | 243.04 | $2.26M | 13,932 | Form 4 |
| 2025-03-10 | Oyler JohnDirector, Chief Executive Officer | Sale | 5,313 | 244.04 | $1.30M | 8,619 | Form 4 |
| 2025-03-10 | Oyler JohnDirector, Chief Executive Officer | Sale | 3,006 | 245.19 | $737,041 | 5,613 | Form 4 |
| 2025-03-10 | Oyler JohnDirector, Chief Executive Officer | Sale | 4,913 | 246.11 | $1.21M | 700 | Form 4 |
| 2025-03-10 | Oyler JohnDirector, Chief Executive Officer | Sale | 700 | 246.85 | $172,795 | 0 | Form 4 |
| 2025-03-07 | Oyler JohnDirector, Chief Executive Officer | Sale | 1,400 | 246.03 | $344,442 | 57,190 | Form 4 |
| 2025-03-07 | Oyler JohnDirector, Chief Executive Officer | Sale | 2,100 | 246.10 | $516,810 | 55,090 | Form 4 |
| 2025-03-07 | Oyler JohnDirector, Chief Executive Officer | Sale | 1,190 | 246.69 | $293,561 | 53,900 | Form 4 |
| 2025-03-07 | Oyler JohnDirector, Chief Executive Officer | Sale | 13,918 | 246.91 | $3.44M | 39,982 | Form 4 |
| 2025-03-07 | Oyler JohnDirector, Chief Executive Officer | Sale | 7,600 | 247.99 | $1.88M | 32,382 | Form 4 |
| 2025-03-07 | Oyler JohnDirector, Chief Executive Officer | Sale | 8,905 | 249.04 | $2.22M | 23,477 | Form 4 |
| 2025-03-07 | Oyler JohnDirector, Chief Executive Officer | Sale | 12,578 | 249.97 | $3.14M | 10,899 | Form 4 |
| 2025-03-07 | Oyler JohnDirector, Chief Executive Officer | Sale | 2,300 | 251.00 | $577,300 | 8,599 | Form 4 |
| 2025-03-07 | Oyler JohnDirector, Chief Executive Officer | Sale | 3,299 | 252.24 | $832,140 | 5,300 | Form 4 |
| 2025-03-07 | Oyler JohnDirector, Chief Executive Officer | Sale | 1,100 | 253.21 | $278,531 | 4,200 | Form 4 |
| 2025-03-07 | Oyler JohnDirector, Chief Executive Officer | Sale | 1,300 | 254.10 | $330,330 | 2,900 | Form 4 |
| 2025-03-07 | Oyler JohnDirector, Chief Executive Officer | Sale | 2,400 | 255.02 | $612,048 | 500 | Form 4 |
| 2025-03-07 | Oyler JohnDirector, Chief Executive Officer | Sale | 500 | 256.10 | $128,050 | 0 | Form 4 |
| 2025-03-06 | Oyler JohnDirector, Chief Executive Officer | Sale | 3,500 | 256.91 | $899,185 | 36,609 | Form 4 |
| 2025-03-06 | Oyler JohnDirector, Chief Executive Officer | Sale | 13,598 | 257.92 | $3.51M | 23,011 | Form 4 |
| 2025-03-06 | Oyler JohnDirector, Chief Executive Officer | Sale | 8,200 | 258.91 | $2.12M | 14,811 | Form 4 |
| 2025-03-06 | Oyler JohnDirector, Chief Executive Officer | Sale | 6,705 | 259.77 | $1.74M | 8,106 | Form 4 |
| 2025-03-06 | Oyler JohnDirector, Chief Executive Officer | Sale | 2,906 | 261.08 | $758,698 | 5,200 | Form 4 |
| 2025-03-06 | Oyler JohnDirector, Chief Executive Officer | Sale | 3,400 | 262.03 | $890,902 | 1,800 | Form 4 |
| 2025-03-06 | Oyler JohnDirector, Chief Executive Officer | Sale | 1,700 | 262.97 | $447,049 | 100 | Form 4 |
| 2025-03-06 | Oyler JohnDirector, Chief Executive Officer | Sale | 100 | 264.27 | $26,427 | 0 | Form 4 |
| 2025-03-05 | Wu XiaobinPresident, COO & GM China | Saleplan | 17,824 | 260.39 | $4.64M | 34,097 | Form 4 |
| 2025-03-05 | Wu XiaobinPresident, COO & GM China | Saleplan | 11,360 | 261.61 | $2.97M | 22,737 | Form 4 |
| 2025-03-05 | Wu XiaobinPresident, COO & GM China | Saleplan | 22,537 | 262.51 | $5.92M | 200 | Form 4 |
| 2025-03-05 | Wu XiaobinPresident, COO & GM China | Saleplan | 200 | 263.00 | $52,600 | 0 | Form 4 |
| 2025-03-04 | Wang XiaodongDirector, Other | Saleplanindirect | 700 | 251.70 | $176,190 | 7,446 | Form 4 |
| 2025-03-04 | Wang XiaodongDirector, Other | Saleplanindirect | 2,000 | 252.72 | $505,440 | 5,446 | Form 4 |
| 2025-03-04 | Wang XiaodongDirector, Other | Saleplanindirect | 825 | 253.55 | $209,179 | 4,621 | Form 4 |
| 2025-03-04 | Wang XiaodongDirector, Other | Saleplanindirect | 1,275 | 254.77 | $324,832 | 3,346 | Form 4 |
| 2025-03-04 | Wang XiaodongDirector, Other | Saleplanindirect | 1,214 | 255.71 | $310,432 | 2,132 | Form 4 |
| 2025-03-04 | Wang XiaodongDirector, Other | Saleplanindirect | 1,809 | 256.83 | $464,605 | 323 | Form 4 |
| 2025-03-04 | Wang XiaodongDirector, Other | Saleplanindirect | 323 | 257.41 | $83,143 | 0 | Form 4 |
| 2025-03-03 | Oyler JohnDirector, Chief Executive Officer | Sale | 5,956 | 240.53 | $1.43M | 95,044 | Form 4 |
| 2025-03-03 | Oyler JohnDirector, Chief Executive Officer | Sale | 13,816 | 241.38 | $3.33M | 81,228 | Form 4 |
| 2025-03-03 | Oyler JohnDirector, Chief Executive Officer | Sale | 8,192 | 242.46 | $1.99M | 73,036 | Form 4 |
| 2025-03-03 | Oyler JohnDirector, Chief Executive Officer | Sale | 11,195 | 243.44 | $2.73M | 61,841 | Form 4 |
| 2025-03-03 | Oyler JohnDirector, Chief Executive Officer | Sale | 4,910 | 244.45 | $1.20M | 56,931 | Form 4 |
| 2025-03-03 | Oyler JohnDirector, Chief Executive Officer | Sale | 18,386 | 244.56 | $4.50M | 38,545 | Form 4 |
| 2025-03-03 | Oyler JohnDirector, Chief Executive Officer | Sale | 1,090 | 245.36 | $267,442 | 37,455 | Form 4 |
| 2025-03-03 | Oyler JohnDirector, Chief Executive Officer | Sale | 19,232 | 245.51 | $4.72M | 18,223 | Form 4 |
| 2025-03-03 | Oyler JohnDirector, Chief Executive Officer | Sale | 7,243 | 246.57 | $1.79M | 10,980 | Form 4 |
| 2025-03-03 | Oyler JohnDirector, Chief Executive Officer | Sale | 6,480 | 247.63 | $1.60M | 4,500 | Form 4 |
| 2025-03-03 | Oyler JohnDirector, Chief Executive Officer | Sale | 3,900 | 248.63 | $969,657 | 600 | Form 4 |
| 2025-03-03 | Oyler JohnDirector, Chief Executive Officer | Sale | 600 | 249.25 | $149,550 | 0 | Form 4 |
| 2025-02-28 | Wu XiaobinPresident, COO & GM China | Saleindirect | 0 | – | – | 0 | Form 4 |
| 2025-02-28 | Baker JulianDirectorwith Baker Felix, Baker Bros. Advisors LP, Baker Brothers Life Sciences LP, 667, L.P., Baker Bros. Advisors (gp) LLC | Saleindirect | 60,851 | 260.00 | $15.82M | 730,642 | Form 4 |
| 2025-02-28 | Baker JulianDirectorwith Baker Felix, Baker Bros. Advisors LP, Baker Brothers Life Sciences LP, 667, L.P., Baker Bros. Advisors (gp) LLC | Saleindirect | 671,976 | 260.00 | $174.71M | 8,068,411 | Form 4 |
| 2025-02-27 | Lee Chan HenrySVP, General Counsel | Saleplan | 1,205 | 275.00 | $331,375 | 0 | Form 4 |
| 2025-02-21 | Lee Chan HenrySVP, General Counsel | Saleplan | 504 | 256.84 | $129,447 | 698 | Form 4 |
| 2025-02-21 | Lee Chan HenrySVP, General Counsel | Saleplan | 598 | 258.69 | $154,697 | 100 | Form 4 |
| 2025-02-21 | Lee Chan HenrySVP, General Counsel | Saleplan | 100 | 260.22 | $26,022 | 0 | Form 4 |
| 2025-02-21 | Wang LaiGlobal Head of R&D | Saleplanindirect | 1,327 | 254.82 | $338,146 | 3,673 | Form 4 |
| 2025-02-21 | Wang LaiGlobal Head of R&D | Saleplanindirect | 575 | 255.86 | $147,120 | 3,098 | Form 4 |
| 2025-02-21 | Wang LaiGlobal Head of R&D | Saleplanindirect | 479 | 256.70 | $122,959 | 2,619 | Form 4 |
| 2025-02-21 | Wang LaiGlobal Head of R&D | Saleplanindirect | 437 | 258.18 | $112,825 | 2,182 | Form 4 |
| 2025-02-21 | Wang LaiGlobal Head of R&D | Saleplanindirect | 1,782 | 258.73 | $461,057 | 400 | Form 4 |
| 2025-02-21 | Wang LaiGlobal Head of R&D | Saleplanindirect | 400 | 260.17 | $104,068 | 0 | Form 4 |
| 2025-02-20 | Wu XiaobinPresident, COO & GM China | Saleplan | 21,267 | 240.07 | $5.11M | 0 | Form 4 |
| 2025-02-18 | Wu XiaobinPresident, COO & GM China | Saleplan | 19,576 | 240.31 | $4.70M | 11,078 | Form 4 |
| 2025-02-18 | Wu XiaobinPresident, COO & GM China | Saleplan | 7,919 | 241.26 | $1.91M | 3,159 | Form 4 |
| 2025-02-18 | Wu XiaobinPresident, COO & GM China | Saleplan | 3,159 | 242.08 | $764,731 | 0 | Form 4 |
| 2025-02-04 | Wang XiaodongDirector, Other | Saleplan | 9,099 | 223.00 | $2.03M | 32,661 | Form 4 |
| 2025-02-04 | Wang XiaodongDirector, Other | Saleplan | 1,519 | 224.18 | $340,529 | 31,142 | Form 4 |
| 2025-02-04 | Wang XiaodongDirector, Other | Saleplan | 2,161 | 225.27 | $486,808 | 28,981 | Form 4 |
| 2025-02-04 | Wang XiaodongDirector, Other | Saleplan | 17,805 | 226.35 | $4.03M | 11,176 | Form 4 |
| 2025-02-04 | Wang XiaodongDirector, Other | Saleplan | 9,776 | 227.00 | $2.22M | 1,400 | Form 4 |
| 2025-02-04 | Wang XiaodongDirector, Other | Saleplan | 1,400 | 228.04 | $319,256 | 0 | Form 4 |
| 2025-01-07 | Wang XiaodongDirector, Other | Saleplan | 19,251 | 175.46 | $3.38M | 22,509 | Form 4 |
| 2025-01-07 | Wang XiaodongDirector, Other | Saleplan | 11,310 | 176.67 | $2.00M | 11,199 | Form 4 |
| 2025-01-07 | Wang XiaodongDirector, Other | Saleplan | 4,260 | 177.42 | $755,809 | 6,939 | Form 4 |
| 2025-01-07 | Wang XiaodongDirector, Other | Saleplan | 5,638 | 178.39 | $1.01M | 1,301 | Form 4 |
| 2025-01-07 | Wang XiaodongDirector, Other | Saleplan | 1,301 | 179.18 | $233,113 | 0 | Form 4 |
| 2024-12-10 | Wang XiaodongDirector, Other | Saleplan | 2,600 | 183.60 | $477,360 | 39,160 | Form 4 |
| 2024-12-10 | Wang XiaodongDirector, Other | Saleplan | 7,063 | 184.83 | $1.31M | 32,097 | Form 4 |
| 2024-12-10 | Wang XiaodongDirector, Other | Saleplan | 9,956 | 185.73 | $1.85M | 22,141 | Form 4 |
| 2024-12-10 | Wang XiaodongDirector, Other | Saleplan | 9,266 | 186.99 | $1.73M | 12,875 | Form 4 |
| 2024-12-10 | Wang XiaodongDirector, Other | Saleplan | 6,350 | 187.60 | $1.19M | 6,525 | Form 4 |
| 2024-12-10 | Wang XiaodongDirector, Other | Saleplan | 1,300 | 188.79 | $245,427 | 5,225 | Form 4 |
And 28 older ones, each in its filing at the SEC.
Grants, exercises and other transactions
Pay, tax and paperwork rather than a choice to trade at the market price. Two years.
86 × option exercise48 × grant or award5 × gift1 × other1 × shares withheld for tax
Show them
| Date | Insider | What | Shares | Price | Holds after | Filing |
|---|---|---|---|---|---|---|
| 2026-09-28 | Wang XiaodongDirector, Other | Option exercise M | +31,028 | 36.90 | 31,028 | Form 4 |
| 2026-09-14 | Baker JulianDirector | Option exercise M | +30,768 | 36.83 | 761,410 | Form 4 |
| 2026-09-14 | Baker JulianDirector | Option exercise M | +30,768 | 36.83 | 8,099,179 | Form 4 |
| 2026-09-08 | Wang XiaodongDirector, Other | Option exercise M | +31,027 | 36.90 | 31,027 | Form 4 |
| 2026-08-11 | Lee Chan HenrySVP, General Counsel | Option exercise M | +812 | 194.47 | 812 | Form 4 |
| 2026-08-11 | Lee Chan HenrySVP, General Counsel | Option exercise M | +1,058 | 213.32 | 1,870 | Form 4 |
| 2026-08-11 | Lee Chan HenrySVP, General Counsel | Option exercise M | +796 | 159.03 | 2,666 | Form 4 |
| 2026-07-22 | Lee Chan HenrySVP, General Counsel | Option exercise M | +514 | 194.47 | 514 | Form 4 |
| 2026-07-22 | Lee Chan HenrySVP, General Counsel | Option exercise M | +665 | 213.32 | 1,179 | Form 4 |
| 2026-07-22 | Lee Chan HenrySVP, General Counsel | Option exercise M | +490 | 159.03 | 1,669 | Form 4 |
| 2026-07-20 | Oyler JohnDirector, Chief Executive Officer | Option exercise M | +33,990 | 119.96 | 33,990 | Form 4 |
| 2026-07-17 | Oyler JohnDirector, Chief Executive Officer | Option exercise M | +64,628 | 119.96 | 64,628 | Form 4 |
| 2026-07-16 | Oyler JohnDirector, Chief Executive Officer | Option exercise M | +96,501 | 160.40 | 96,501 | Form 4 |
| 2026-07-16 | Oyler JohnDirector, Chief Executive Officer | Option exercise M | +70,096 | 119.96 | 166,597 | Form 4 |
| 2026-07-15 | Oyler JohnDirector, Chief Executive Officer | Option exercise M | +35,605 | 100.04 | 35,605 | Form 4 |
| 2026-07-15 | Oyler JohnDirector, Chief Executive Officer | Option exercise M | +76,677 | 169.58 | 112,282 | Form 4 |
| 2026-07-15 | Oyler JohnDirector, Chief Executive Officer | Option exercise M | +4,275 | 160.40 | 116,557 | Form 4 |
| 2026-07-14 | Oyler JohnDirector, Chief Executive Officer | Option exercise M | +97,282 | 36.90 | 97,282 | Form 4 |
| 2026-07-14 | Oyler JohnDirector, Chief Executive Officer | Option exercise M | +36,318 | 100.04 | 133,600 | Form 4 |
| 2026-07-13 | Oyler JohnDirector, Chief Executive Officer | Option exercise M | +48,520 | 36.90 | 48,520 | Form 4 |
| 2026-07-10 | Oyler JohnDirector, Chief Executive Officer | Option exercise M | +11,698 | 36.90 | 11,698 | Form 4 |
| 2026-07-08 | Lee Chan HenrySVP, General Counsel | Option exercise M | +202 | 194.47 | 202 | Form 4 |
| 2026-07-08 | Lee Chan HenrySVP, General Counsel | Option exercise M | +266 | 213.32 | 468 | Form 4 |
| 2026-07-08 | Lee Chan HenrySVP, General Counsel | Option exercise M | +196 | 159.03 | 664 | Form 4 |
| 2026-06-11 | Oyler JohnDirector, Chief Executive Officer | Grant or award A | +177,931 | – | 5,697,649 | Form 4 |
| 2026-06-11 | Baker JulianDirector | Grant or award A | +18,980 | – | 161,546 | Form 4 |
| 2026-06-11 | Baker JulianDirector | Grant or award A | +18,980 | – | 161,550 | Form 4 |
| 2026-06-11 | Hooper Anthony CDirector | Grant or award A | +18,980 | – | 83,720 | Form 4 |
| 2026-06-11 | Sharp ShaliniDirector | Grant or award A | +18,980 | – | 38,116 | Form 4 |
| 2026-06-11 | Brandicourt OlivierDirector | Grant or award A | +18,980 | – | 46,306 | Form 4 |
| 2026-06-11 | Wang XiaodongDirector, Other | Grant or award A | +99,892 | – | 4,682,493 | Form 4 |
| 2026-06-11 | Ball Titus B.Principal Accounting Officer | Grant or award A | +31,213 | – | 99,645 | Form 4 |
| 2026-06-11 | Wu XiaobinPresident and COO | Grant or award A | +118,625 | – | 1,308,161 | Form 4 |
| 2026-06-11 | Wang LaiPresident, Global Head of R&D | Grant or award A | +118,625 | – | 1,710,085 | Form 4 |
| 2026-06-11 | Riva AlessandroDirector | Grant or award A | +18,980 | – | 73,164 | Form 4 |
| 2026-06-11 | Dugan MargaretDirector | Grant or award A | +18,980 | – | 73,164 | Form 4 |
| 2026-06-11 | Lee Chan HenrySVP, General Counsel | Grant or award A | +45,071 | – | 346,554 | Form 4 |
| 2026-06-11 | Rosenberg AaronChief Financial Officer | Grant or award A | +71,175 | – | 397,891 | Form 4 |
| 2026-06-11 | Sawyers Charles LazelleDirector | Grant or award A | +18,980 | – | 18,984 | Form 4 |
| 2026-06-11 | Mooney Elizabeth FisherDirector | Grant or award A | +18,980 | – | 18,980 | Form 4 |
| 2026-05-13 | Lee Chan HenrySVP, General Counsel | Option exercise M | +101 | 194.47 | 101 | Form 4 |
| 2026-05-13 | Lee Chan HenrySVP, General Counsel | Option exercise M | +133 | 213.32 | 234 | Form 4 |
| 2026-05-13 | Lee Chan HenrySVP, General Counsel | Option exercise M | +98 | 159.03 | 332 | Form 4 |
| 2026-04-08 | Lee Chan HenrySVP, General Counsel | Option exercise M | +101 | 194.47 | 101 | Form 4 |
| 2026-04-08 | Lee Chan HenrySVP, General Counsel | Option exercise M | +133 | 213.32 | 234 | Form 4 |
| 2026-04-08 | Lee Chan HenrySVP, General Counsel | Option exercise M | +98 | 159.03 | 332 | Form 4 |
| 2026-03-11 | Lee Chan HenrySVP, General Counsel | Option exercise M | +110 | 194.47 | 110 | Form 4 |
| 2026-03-11 | Lee Chan HenrySVP, General Counsel | Option exercise M | +133 | 213.32 | 243 | Form 4 |
| 2026-03-11 | Lee Chan HenrySVP, General Counsel | Option exercise M | +98 | 159.03 | 341 | Form 4 |
| 2026-03-06 | Oyler JohnDirector, Chief Executive Officer | Grant or award A | +326,976 | – | 5,491,339 | Form 4 |
| 2026-03-06 | Oyler JohnDirector, Chief Executive Officer | Grant or award A | +117,936 | – | 5,609,275 | Form 4 |
| 2026-03-06 | Wu XiaobinPresident and COO | Grant or award A | +168,922 | – | 1,137,900 | Form 4 |
| 2026-03-06 | Wu XiaobinPresident and COO | Grant or award A | +78,624 | – | 1,216,524 | Form 4 |
| 2026-03-06 | Wang LaiPresident, Global Head of R&D | Grant or award A | +112,606 | – | 1,564,030 | Form 4 |
| 2026-03-06 | Wang LaiPresident, Global Head of R&D | Grant or award A | +55,029 | – | 1,619,059 | Form 4 |
| 2026-03-06 | Lee Chan HenrySVP, General Counsel | Grant or award A | +65,390 | – | 288,496 | Form 4 |
| 2026-03-06 | Lee Chan HenrySVP, General Counsel | Grant or award A | +29,874 | – | 318,370 | Form 4 |
| 2026-03-06 | Rosenberg AaronChief Financial Officer | Grant or award A | +79,014 | – | 294,346 | Form 4 |
| 2026-03-06 | Rosenberg AaronChief Financial Officer | Grant or award A | +40,573 | – | 334,919 | Form 4 |
| 2026-02-04 | Lee Chan HenrySVP, General Counsel | Option exercise M | +502 | 194.47 | 502 | Form 4 |
| 2026-02-04 | Lee Chan HenrySVP, General Counsel | Option exercise M | +662 | 213.32 | 1,164 | Form 4 |
| 2026-02-04 | Lee Chan HenrySVP, General Counsel | Option exercise M | +496 | 159.03 | 1,660 | Form 4 |
| 2026-01-07 | Lee Chan HenrySVP, General Counsel | Option exercise M | +202 | 194.47 | 202 | Form 4 |
| 2026-01-07 | Lee Chan HenrySVP, General Counsel | Option exercise M | +266 | 213.32 | 468 | Form 4 |
| 2026-01-07 | Lee Chan HenrySVP, General Counsel | Option exercise M | +196 | 159.03 | 664 | Form 4 |
| 2025-12-31 | Wang LaiPresident, Global Head of R&D | Grant or award A | +427,895 | – | 1,451,424 | Form 4 |
| 2025-12-11 | Lee Chan HenrySVP, General Counsel | Option exercise M | +101 | 194.47 | 101 | Form 4 |
| 2025-12-11 | Lee Chan HenrySVP, General Counsel | Option exercise M | +133 | 213.32 | 234 | Form 4 |
| 2025-12-11 | Lee Chan HenrySVP, General Counsel | Option exercise M | +98 | 159.03 | 332 | Form 4 |
| 2025-12-10 | Lee Chan HenrySVP, General Counsel | Option exercise M | +101 | 194.47 | 101 | Form 4 |
| 2025-12-10 | Lee Chan HenrySVP, General Counsel | Option exercise M | +133 | 213.32 | 234 | Form 4 |
| 2025-12-10 | Lee Chan HenrySVP, General Counsel | Option exercise M | +98 | 159.03 | 332 | Form 4 |
| 2025-11-26 | Sanders Corazon (Corsee) D.Director | Option exercise M | +2,627 | 159.03 | 2,627 | Form 4 |
| 2025-11-12 | Lee Chan HenrySVP, General Counsel | Option exercise M | +302 | 194.47 | 302 | Form 4 |
| 2025-11-12 | Lee Chan HenrySVP, General Counsel | Option exercise M | +398 | 213.32 | 700 | Form 4 |
| 2025-11-12 | Lee Chan HenrySVP, General Counsel | Option exercise M | +296 | 159.03 | 996 | Form 4 |
| 2025-11-12 | Oyler JohnDirector, Chief Executive Officer | Gift G | −858,533 | – | 6,441,041 | Form 4 |
| 2025-11-11 | Oyler JohnDirector, Chief Executive Officer | Gift G | −151,320 | – | 7,299,574 | Form 4 |
| 2025-11-07 | Wang XiaodongDirector, Other | Gift G | −424,073 | – | 4,582,601 | Form 4 |
| 2025-10-08 | Lee Chan HenrySVP, General Counsel | Option exercise M | +302 | 194.47 | 302 | Form 4 |
| 2025-10-08 | Lee Chan HenrySVP, General Counsel | Option exercise M | +8,961 | 213.32 | 9,263 | Form 4 |
| 2025-10-08 | Lee Chan HenrySVP, General Counsel | Option exercise M | +296 | 159.03 | 9,559 | Form 4 |
| 2025-09-10 | Lee Chan HenrySVP, General Counsel | Option exercise M | +6,802 | 194.47 | 6,802 | Form 4 |
| 2025-09-10 | Lee Chan HenrySVP, General Counsel | Option exercise M | +1,796 | 213.32 | 8,598 | Form 4 |
| 2025-09-10 | Lee Chan HenrySVP, General Counsel | Option exercise M | +296 | 159.03 | 8,894 | Form 4 |
| 2025-09-09 | Wang XiaodongDirector, Other | Gift G | −148,096 | – | 5,006,674 | Form 4 |
| 2025-09-05 | Sanders Corazon (Corsee) D.Director | Option exercise M | +2,665 | 155.68 | 2,665 | Form 4 |
| 2025-08-14 | Wu XiaobinPresident and COO | Option exercise M | +30,756 | 155.68 | 30,756 | Form 4 |
| 2025-08-14 | Wu XiaobinPresident and COO | Option exercise M | +9,180 | 159.03 | 39,936 | Form 4 |
| 2025-08-13 | Lee Chan HenrySVP, General Counsel | Option exercise M | +4,381 | 194.47 | 4,381 | Form 4 |
| 2025-08-13 | Lee Chan HenrySVP, General Counsel | Option exercise M | +3,849 | 159.03 | 8,230 | Form 4 |
| 2025-08-13 | Wu XiaobinPresident and COO | Option exercise M | +22,773 | 174.43 | 22,773 | Form 4 |
| 2025-08-13 | Wu XiaobinPresident and COO | Option exercise M | +27,085 | 155.68 | 49,858 | Form 4 |
| 2025-06-10 | Yi QingqingDirector | Other J | −29,614 | – | 27,326 | Form 4 |
| 2025-06-10 | Oyler JohnDirector, Chief Executive Officer | Grant or award A | +185,055 | – | 8,281,841 | Form 4 |
| 2025-06-10 | Wang XiaodongDirector, Other | Grant or award A | +98,696 | – | 5,180,861 | Form 4 |
| 2025-06-10 | Wang XiaodongDirector, Other | Option exercise M | +41,760 | 6.50 | 41,760 | Form 4 |
| 2025-06-10 | Wu XiaobinPresident and COO | Grant or award A | +123,370 | – | 1,274,296 | Form 4 |
| 2025-06-10 | Wang LaiGlobal Head of R&D | Grant or award A | +86,359 | – | 1,058,304 | Form 4 |
| 2025-06-10 | Rosenberg AaronChief Financial Officer | Grant or award A | +63,674 | – | 230,802 | Form 4 |
| 2025-06-10 | Lee Chan HenrySVP, General Counsel | Grant or award A | +46,878 | – | 283,920 | Form 4 |
| 2025-06-10 | Ball Titus B.Principal Accounting Officer | Grant or award A | +29,601 | – | 73,983 | Form 4 |
| 2025-05-21 | Yi QingqingDirector | Grant or award A | +10,985 | – | 56,940 | Form 4 |
| 2025-05-21 | Baker JulianDirector | Grant or award A | +21,970 | – | 148,065 | Form 4 |
| 2025-05-21 | Baker JulianDirector | Grant or award A | +21,970 | – | 148,069 | Form 4 |
| 2025-05-21 | Hooper Anthony CDirector | Grant or award A | +10,985 | – | 64,740 | Form 4 |
| 2025-05-21 | Sanders Corazon (Corsee) D.Director | Grant or award A | +10,985 | – | 57,226 | Form 4 |
| 2025-05-21 | Dugan MargaretDirector | Grant or award A | +10,985 | – | 56,940 | Form 4 |
| 2025-05-21 | Riva AlessandroDirector | Grant or award A | +10,985 | – | 56,940 | Form 4 |
| 2025-05-21 | Brandicourt OlivierDirector | Grant or award A | +10,985 | – | 27,326 | Form 4 |
| 2025-05-21 | Sharp ShaliniDirector | Grant or award A | +10,985 | – | 19,136 | Form 4 |
| 2025-05-13 | Wang XiaodongDirector, Other | Option exercise M | +41,760 | 6.50 | 41,760 | Form 4 |
| 2025-05-09 | Oyler JohnDirector, Chief Executive Officer | Option exercise M | +4,055,415 | 0.50 | 10,154,040 | Form 4 |
| 2025-05-09 | Oyler JohnDirector, Chief Executive Officer | Shares withheld for tax F | −1,990,603 | 17.85 | 8,163,437 | Form 4 |
| 2025-04-14 | Wang XiaodongDirector, Other | Option exercise M | +41,760 | 6.50 | 41,760 | Form 4 |
| 2025-04-01 | Wu XiaobinPresident, COO & GM China | Option exercise M | +16,477 | 119.96 | 16,477 | Form 4 |
| 2025-04-01 | Wu XiaobinPresident, COO & GM China | Option exercise M | +35,444 | 174.43 | 51,921 | Form 4 |
| 2025-03-18 | Wang XiaodongDirector, Other | Option exercise M | +41,760 | 6.50 | 41,760 | Form 4 |
| 2025-03-11 | Wang XiaodongDirector, Other | Gift G | −158,717 | – | 5,082,165 | Form 4 |
| 2025-03-10 | Oyler JohnDirector, Chief Executive Officer | Option exercise M | +497,822 | 0.50 | 6,098,625 | Form 4 |
| 2025-03-10 | Oyler JohnDirector, Chief Executive Officer | Option exercise M | +41,210 | 6.50 | 41,210 | Form 4 |
| 2025-03-07 | Oyler JohnDirector, Chief Executive Officer | Option exercise M | +708,747 | 0.50 | 5,600,803 | Form 4 |
| 2025-03-07 | Oyler JohnDirector, Chief Executive Officer | Option exercise M | +58,590 | 6.50 | 58,590 | Form 4 |
| 2025-03-06 | Oyler JohnDirector, Chief Executive Officer | Option exercise M | +486,161 | 0.50 | 4,892,056 | Form 4 |
| 2025-03-06 | Oyler JohnDirector, Chief Executive Officer | Option exercise M | +40,109 | 6.50 | 40,109 | Form 4 |
| 2025-03-05 | Rosenberg AaronChief Financial Officer | Grant or award A | +48,581 | – | 167,128 | Form 4 |
| 2025-03-05 | Lee Chan HenrySVP, General Counsel | Grant or award A | +40,209 | – | 246,142 | Form 4 |
| 2025-03-05 | Wang LaiGlobal Head of R&D | Grant or award A | +69,251 | – | 990,171 | Form 4 |
| 2025-03-05 | Wu XiaobinPresident, COO & GM China | Grant or award A | +103,883 | – | 1,175,210 | Form 4 |
| 2025-03-05 | Wu XiaobinPresident, COO & GM China | Option exercise M | +7,048 | 169.65 | 7,048 | Form 4 |
| 2025-03-05 | Wu XiaobinPresident, COO & GM China | Option exercise M | +44,873 | 119.96 | 51,921 | Form 4 |
| 2025-03-05 | Oyler JohnDirector, Chief Executive Officer | Grant or award A | +201,084 | – | 4,405,895 | Form 4 |
| 2025-03-03 | Oyler JohnDirector, Chief Executive Officer | Option exercise M | +1,220,531 | 0.50 | 4,199,364 | Form 4 |
| 2025-03-03 | Oyler JohnDirector, Chief Executive Officer | Option exercise M | +101,000 | 6.50 | 101,000 | Form 4 |
| 2025-02-20 | Wu XiaobinPresident, COO & GM China | Option exercise M | +21,267 | 169.65 | 21,267 | Form 4 |
| 2025-02-18 | Wu XiaobinPresident, COO & GM China | Option exercise M | +30,654 | 169.65 | 30,654 | Form 4 |
| 2025-02-04 | Wang XiaodongDirector, Other | Option exercise M | +41,760 | 6.50 | 41,760 | Form 4 |
| 2025-01-07 | Wang XiaodongDirector, Other | Option exercise M | +41,760 | 6.50 | 41,760 | Form 4 |
| 2024-12-14 | Oyler JohnDirector, Chief Executive Officer | Option exercise M | +1,300,000 | 0.50 | 2,978,833 | Form 4 |
| 2024-12-10 | Wang XiaodongDirector, Other | Option exercise M | +41,760 | 6.50 | 41,760 | Form 4 |
| 2024-11-26 | Wang XiaodongDirector, Other | Option exercise M | +38,461 | 6.50 | 40,468 | Form 4 |
How to read it
- Buy, sale
- Code P and S on the form: shares bought or sold in the market, at the market price. The other codes are mostly pay (a grant, an option exercised) or tax (shares the company withheld), and say little about what the insider thinks of the price.
- Plan
- A sale or purchase under a Rule 10b5-1 plan, set up in advance and running on its own schedule. Since April 2023 the form has a box for it. Much executive selling is planned and says more about diversifying than about the company.
- Holds after
- The shares the insider still held after the trade, in the form the trade was in (directly, or indirectly through a trust or a fund).
- Value
- Shares times the price the form reports, which is often an average over several fills on the day.
Read from the SEC's own quarterly data sets of Forms 3, 4 and 5, and from each day's filings since the last one. A correcting amendment replaces the lines it restates. Every row links to its filing. None of this is advice: insiders sell for many reasons, and buy for fewer.