Ionis Pharmaceuticals Inc (IONS) · Insider trading
What Ionis Pharmaceuticals's directors, officers and largest holders bought and sold themselves, from the Form 4 each of them files with the SEC within two business days of a trade. Open-market purchases and sales first: those are the trades somebody chose to make at the market price.
Bought, 12 months
$1.06M
1 insider, 2 trades
Sold, 12 months
$134.02M
19 insiders, 83% under a plan
Net, 12 months
−$132.96M
bought less sold
Latest filing
2026-09-02
filings read to 2026-10-19
Who traded, two years
| Insider | Bought | Sold | Trades | Last trade | Holds after |
|---|---|---|---|---|---|
| Monia Brett PDirector, Chief Executive Officer | – | $45.81M | 24 | 2026-06-26 | 245,571 |
| Hougen Elizabeth LEVP, Finance & CFO | – | $21.46M | 8 | 2026-03-17 | 82,660 |
| Bennett C FrankEVP, Chief Scientific Officer | – | $20.07M | 16 | 2026-07-07 | 75,018 |
| O'Neil Patrick R.EVP CLO & General Counsel | – | $16.56M | 20 | 2026-06-26 | 61,470 |
| Geary Richard SEVP, Chief Development Officer | – | $14.44M | 14 | 2025-11-06 | 59,657 |
| Klein Joseph IIIDirector | – | $9.36M | 14 | 2026-07-01 | 22,433 |
| Devers Shannon L.EVP, Chief Human Resources Ofc | – | $8.99M | 16 | 2026-04-02 | 16,348 |
| Wender Joseph HDirector | – | $8.66M | 13 | 2025-12-01 | – |
| Loscalzo JosephDirector | – | $8.56M | 7 | 2026-05-04 | 54,111 |
| Swayze EricEVP Research | – | $8.38M | 18 | 2026-06-25 | 21,759 |
| Baroldi JosephEVP, Chief Business Officer | – | $6.66M | 20 | 2026-06-26 | – |
| Schneider EugeneEVP, Chf Clinical Develop Ofcr | – | $5.60M | 9 | 2026-06-26 | 77,114 |
| Diaz Allene M.Director | – | $5.28M | 5 | 2026-07-07 | 3,811 |
| Kordasiewicz Holly B.EVP, Chief Development Officer | – | $4.81M | 4 | 2026-07-07 | 22,096 |
| Birchler BrianEVP, Corp and Development Ops | – | $3.75M | 8 | 2026-04-16 | 67,500 |
| Jenne KyleEVP, Chf GL Pdt Str Ofcr | – | $3.42M | 5 | 2026-04-16 | 23,713 |
| Herman Joan eDirector | – | $3.17M | 2 | 2025-11-19 | 46,086 |
| Parshall B LynneDirector | – | $2.38M | 8 | 2026-04-15 | 51,878 |
| Hayden Michael RDirector | $1.72M | – | 5 | 2026-07-31 | – |
| Berthelsen Spencer RDirector | – | $1.19M | 2 | 2026-06-15 | 156,013 |
Open-market purchases and sales
Newest first. “Plan” marks a trade made under a 10b5-1 plan set up in advance.
| Date | Insider | Trade | Shares | Price | Value | Holds after | Filing |
|---|---|---|---|---|---|---|---|
| 2026-07-31 | Hayden Michael RDirector | Buyindirect | 5,000 | 51.60 | $258,000 | 24,000 | Form 4 |
| 2026-07-30 | Hayden Michael RDirector | Buyindirect | 15,000 | 53.38 | $800,700 | 19,000 | Form 4 |
| 2026-07-07 | Kordasiewicz Holly B.EVP, Chief Development Officer | Saleplan | 362 | 84.30 | $30,517 | 22,096 | Form 4 |
| 2026-07-07 | Diaz Allene M.Director | Saleplan | 10,111 | 85.42 | $863,682 | 3,811 | Form 4 |
| 2026-07-07 | Bennett C FrankEVP, Chief Scientific Officer | Saleplan | 5,536 | 83.58 | $462,699 | 75,018 | Form 4 |
| 2026-07-07 | Bennett C FrankEVP, Chief Scientific Officer | Saleplanindirect | 15,000 | 85.46 | $1.28M | 0 | Form 4 |
| 2026-07-01 | Klein Joseph IIIDirector | Saleplan | 99 | 79.45 | $7,866 | 22,433 | Form 4 |
| 2026-07-01 | Klein Joseph IIIDirector | Saleplan | 11,419 | 79.04 | $902,558 | 11,014 | Form 4 |
| 2026-06-26 | Schneider EugeneEVP, Chf Clinical Develop Ofcr | Saleplan | 26,000 | 81.05 | $2.11M | 77,114 | Form 4 |
| 2026-06-26 | O'Neil Patrick R.EVP CLO & General Counsel | Saleplan | 3,069 | 80.00 | $245,520 | 61,470 | Form 4 |
| 2026-06-26 | Baroldi JosephEVP, Chief Business Officer | Saleplanindirect | 5,635 | 80.16 | $451,702 | 4,669 | Form 4 |
| 2026-06-26 | Monia Brett PDirector, Chief Executive Officer | Saleplan | 50,000 | 80.59 | $4.03M | 245,571 | Form 4 |
| 2026-06-25 | Swayze EricEVP Research | Saleplan | 10,602 | 79.18 | $839,466 | 21,759 | Form 4 |
| 2026-06-25 | Monia Brett PDirector, Chief Executive Officer | Saleplan | 21,072 | 78.49 | $1.65M | 245,571 | Form 4 |
| 2026-06-24 | Monia Brett PDirector, Chief Executive Officer | Saleplan | 14,565 | 78.41 | $1.14M | 245,571 | Form 4 |
| 2026-06-15 | Berthelsen Spencer RDirector | Saleplan | 8,000 | 73.49 | $587,920 | 156,013 | Form 4 |
| 2026-06-12 | Kordasiewicz Holly B.EVP, Chief Development Officer | Saleplan | 41,004 | 73.09 | $3.00M | 42,300 | Form 4 |
| 2026-06-12 | Kordasiewicz Holly B.EVP, Chief Development Officer | Saleplan | 19,842 | 74.05 | $1.47M | 22,458 | Form 4 |
| 2026-06-01 | Berthelsen Spencer RDirector | Saleplan | 8,000 | 75.67 | $605,360 | 156,013 | Form 4 |
| 2026-05-14 | Monia Brett PDirector, Chief Executive Officer | Saleplan | 3,220 | 78.68 | $253,350 | 242,662 | Form 4 |
| 2026-05-13 | Monia Brett PDirector, Chief Executive Officer | Saleplan | 1,316 | 78.01 | $102,661 | 242,662 | Form 4 |
| 2026-05-04 | Loscalzo JosephDirector | Saleplan | 59,508 | 74.90 | $4.46M | 54,111 | Form 4 |
| 2026-05-04 | Loscalzo JosephDirector | Saleplan | 17,781 | 75.58 | $1.34M | 36,330 | Form 4 |
| 2026-05-01 | Klein Joseph IIIDirector | Saleplan | 8,680 | 73.35 | $636,678 | 12,445 | Form 4 |
| 2026-05-01 | Klein Joseph IIIDirector | Saleplan | 1,431 | 74.45 | $106,538 | 11,014 | Form 4 |
| 2026-04-28 | Baroldi JosephEVP, Chief Business Officer | Saleplan | 1,626 | 71.79 | $116,731 | 44,909 | Form 4 |
| 2026-04-16 | Baroldi JosephEVP, Chief Business Officer | Sale | 5,619 | 74.56 | $418,953 | 46,535 | Form 4 |
| 2026-04-16 | Birchler BrianEVP, Corp and Development Ops | Sale | 973 | 75.04 | $73,014 | 67,500 | Form 4 |
| 2026-04-16 | Jenne KyleEVP, Chf GL Pdt Str Ofcr | Sale | 4,902 | 75.17 | $368,483 | 23,713 | Form 4 |
| 2026-04-15 | Parshall B LynneDirector | Saleplan | 4,466 | 76.19 | $340,265 | 51,878 | Form 4 |
| 2026-04-15 | Parshall B LynneDirector | Saleplan | 534 | 76.97 | $41,102 | 51,344 | Form 4 |
| 2026-04-02 | Devers Shannon L.EVP, Chief Human Resources Ofc | Saleplan | 6,193 | 74.05 | $458,592 | 16,348 | Form 4 |
| 2026-04-01 | Klein Joseph IIIDirector | Saleplan | 20,105 | 75.50 | $1.52M | 13,230 | Form 4 |
| 2026-04-01 | Klein Joseph IIIDirector | Saleplan | 2,216 | 75.95 | $168,305 | 11,014 | Form 4 |
| 2026-03-19 | Schneider EugeneEVP, Chf Clinical Develop Ofcr | Saleplan | 5,812 | 70.97 | $412,478 | 63,890 | Form 4 |
| 2026-03-17 | Hougen Elizabeth LEVP, Finance & CFO | Saleplan | 10,172 | 73.21 | $744,692 | 82,660 | Form 4 |
| 2026-03-16 | Hougen Elizabeth LEVP, Finance & CFO | Saleplan | 205,608 | 72.38 | $14.88M | 102,272 | Form 4 |
| 2026-03-16 | Hougen Elizabeth LEVP, Finance & CFO | Saleplan | 9,440 | 72.77 | $686,949 | 92,832 | Form 4 |
| 2026-03-10 | Jenne KyleEVP, Chf GL Pdt Str Ofcr | Saleplan | 21,191 | 75.50 | $1.60M | 27,800 | Form 4 |
| 2026-03-10 | Jenne KyleEVP, Chf GL Pdt Str Ofcr | Saleplan | 16,086 | 76.30 | $1.23M | 11,714 | Form 4 |
178 more
| 2026-03-10 | Monia Brett PDirector, Chief Executive Officer | Saleplan | 16,512 | 75.47 | $1.25M | 260,253 | Form 4 |
| 2026-03-10 | Monia Brett PDirector, Chief Executive Officer | Saleplan | 17,591 | 76.34 | $1.34M | 242,662 | Form 4 |
| 2026-03-09 | Monia Brett PDirector, Chief Executive Officer | Saleplan | 7,382 | 74.11 | $547,080 | 361,950 | Form 4 |
| 2026-03-09 | Monia Brett PDirector, Chief Executive Officer | Saleplan | 117,604 | 75.26 | $8.85M | 244,346 | Form 4 |
| 2026-03-09 | Monia Brett PDirector, Chief Executive Officer | Saleplan | 1,684 | 75.58 | $127,277 | 242,662 | Form 4 |
| 2026-03-09 | O'Neil Patrick R.EVP CLO & General Counsel | Saleplan | 10,148 | 75.25 | $763,637 | 62,211 | Form 4 |
| 2026-03-04 | Baroldi JosephEVP, Chief Business Officer | Saleplanindirect | 238 | 80.00 | $19,040 | 4,347 | Form 4 |
| 2026-03-04 | Baroldi JosephEVP, Chief Business Officer | Saleplanindirect | 201 | 80.00 | $16,080 | 4,347 | Form 4 |
| 2026-03-04 | Loscalzo JosephDirector | Saleplan | 200 | 80.00 | $16,000 | 36,330 | Form 4 |
| 2026-03-03 | Baroldi JosephEVP, Chief Business Officer | Saleplan | 4,096 | 79.36 | $325,059 | 41,317 | Form 4 |
| 2026-03-03 | Baroldi JosephEVP, Chief Business Officer | Saleplanindirect | 2,088 | 80.41 | $167,896 | 4,383 | Form 4 |
| 2026-03-03 | Baroldi JosephEVP, Chief Business Officer | Saleplanindirect | 36 | 81.01 | $2,916 | 4,347 | Form 4 |
| 2026-03-03 | Bennett C FrankEVP, Chief Scientific Officer | Saleplan | 71,600 | 79.10 | $5.66M | 94,043 | Form 4 |
| 2026-03-03 | Bennett C FrankEVP, Chief Scientific Officer | Saleplan | 12,687 | 79.88 | $1.01M | 81,356 | Form 4 |
| 2026-03-03 | Bennett C FrankEVP, Chief Scientific Officer | Saleplan | 802 | 80.76 | $64,770 | 80,554 | Form 4 |
| 2026-03-03 | Devers Shannon L.EVP, Chief Human Resources Ofc | Saleplan | 14,321 | 79.12 | $1.13M | 28,326 | Form 4 |
| 2026-03-03 | Devers Shannon L.EVP, Chief Human Resources Ofc | Saleplan | 5,030 | 80.00 | $402,400 | 23,296 | Form 4 |
| 2026-03-03 | Devers Shannon L.EVP, Chief Human Resources Ofc | Saleplan | 755 | 80.84 | $61,034 | 22,541 | Form 4 |
| 2026-03-03 | Diaz Allene M.Director | Saleplan | 39,265 | 79.11 | $3.11M | 19,424 | Form 4 |
| 2026-03-03 | Diaz Allene M.Director | Saleplan | 14,608 | 79.88 | $1.17M | 4,816 | Form 4 |
| 2026-03-03 | Diaz Allene M.Director | Saleplan | 1,005 | 80.80 | $81,204 | 3,811 | Form 4 |
| 2026-03-03 | Klein Joseph IIIDirector | Saleplan | 13,526 | 79.17 | $1.07M | 18,820 | Form 4 |
| 2026-03-03 | Klein Joseph IIIDirector | Saleplan | 6,794 | 80.00 | $543,520 | 12,026 | Form 4 |
| 2026-03-03 | Klein Joseph IIIDirector | Saleplan | 1,012 | 80.82 | $81,790 | 11,014 | Form 4 |
| 2026-03-03 | Loscalzo JosephDirector | Saleplan | 832 | 80.33 | $66,835 | 36,330 | Form 4 |
| 2026-02-13 | Swayze EricEVP Research | Saleplan | 9,435 | 81.56 | $769,519 | 38,312 | Form 4 |
| 2026-02-13 | Swayze EricEVP Research | Saleplan | 6,207 | 82.07 | $509,408 | 32,105 | Form 4 |
| 2026-02-11 | Parshall B LynneDirector | Saleplan | 5,000 | 82.72 | $413,600 | 56,344 | Form 4 |
| 2026-02-06 | Monia Brett PDirector, Chief Executive Officer | Saleplan | 29,430 | 85.79 | $2.52M | 254,497 | Form 4 |
| 2026-02-02 | Bennett C FrankEVP, Chief Scientific Officer | Saleplan | 20,000 | 82.60 | $1.65M | 80,293 | Form 4 |
| 2026-02-02 | Bennett C FrankEVP, Chief Scientific Officer | Saleplan | 48,626 | 83.03 | $4.04M | 80,293 | Form 4 |
| 2026-02-02 | Bennett C FrankEVP, Chief Scientific Officer | Saleplan | 16,463 | 83.03 | $1.37M | 80,293 | Form 4 |
| 2026-01-30 | Baroldi JosephEVP, Chief Business Officer | Sale | 5,296 | 82.96 | $439,356 | 45,413 | Form 4 |
| 2026-01-30 | Bennett C FrankEVP, Chief Scientific Officer | Sale | 5,885 | 82.95 | $488,161 | 100,293 | Form 4 |
| 2026-01-30 | Birchler BrianEVP, Corp and Development Ops | Sale | 6,179 | 83.03 | $513,042 | 66,247 | Form 4 |
| 2026-01-30 | Hougen Elizabeth LEVP, Finance & CFO | Sale | 6,988 | 83.24 | $581,681 | 132,881 | Form 4 |
| 2026-01-30 | Monia Brett PDirector, Chief Executive Officer | Sale | 62,970 | 82.72 | $5.21M | 283,927 | Form 4 |
| 2026-01-30 | O'Neil Patrick R.EVP CLO & General Counsel | Sale | 6,179 | 83.53 | $516,132 | 71,983 | Form 4 |
| 2026-01-30 | Schneider EugeneEVP, Chf Clinical Develop Ofcr | Sale | 6,179 | 83.45 | $515,638 | 69,702 | Form 4 |
| 2026-01-30 | Swayze EricEVP Research | Sale | 6,179 | 82.93 | $512,424 | 47,747 | Form 4 |
| 2026-01-22 | Devers Shannon L.EVP, Chief Human Resources Ofc | Saleplan | 3,977 | 81.34 | $323,489 | 22,541 | Form 4 |
| 2026-01-16 | Baroldi JosephEVP, Chief Business Officer | Sale | 6,907 | 75.75 | $523,205 | 40,431 | Form 4 |
| 2026-01-16 | Baroldi JosephEVP, Chief Business Officer | Saleindirect | 1,149 | 75.78 | $87,071 | 4,772 | Form 4 |
| 2026-01-16 | Bennett C FrankEVP, Chief Scientific Officer | Sale | 8,977 | 75.15 | $674,622 | 94,757 | Form 4 |
| 2026-01-16 | Birchler BrianEVP, Corp and Development Ops | Sale | 8,480 | 75.11 | $636,933 | 60,435 | Form 4 |
| 2026-01-16 | Devers Shannon L.EVP, Chief Human Resources Ofc | Sale | 8,353 | 75.95 | $634,410 | 26,518 | Form 4 |
| 2026-01-16 | Hougen Elizabeth LEVP, Finance & CFO | Sale | 12,922 | 75.22 | $971,993 | 126,307 | Form 4 |
| 2026-01-16 | Jenne KyleEVP, Chf GL Pdt Str Ofcr | Sale | 1,823 | 75.96 | $138,475 | 16,389 | Form 4 |
| 2026-01-16 | Kordasiewicz Holly B.EVP, Chief Development Officer | Sale | 4,141 | 75.66 | $313,308 | 14,718 | Form 4 |
| 2026-01-16 | Monia Brett PDirector, Chief Executive Officer | Sale | 44,034 | 74.82 | $3.29M | 224,683 | Form 4 |
| 2026-01-16 | O'Neil Patrick R.EVP CLO & General Counsel | Sale | 9,191 | 75.84 | $697,045 | 66,171 | Form 4 |
| 2026-01-16 | Schneider EugeneEVP, Chf Clinical Develop Ofcr | Sale | 9,302 | 75.59 | $703,138 | 63,890 | Form 4 |
| 2026-01-16 | Swayze EricEVP Research | Sale | 9,884 | 75.34 | $744,661 | 41,935 | Form 4 |
| 2026-01-16 | Swayze EricEVP Research | Saleindirect | 49 | 75.97 | $3,723 | 318 | Form 4 |
| 2026-01-07 | Devers Shannon L.EVP, Chief Human Resources Ofc | Saleplan | 25,545 | 85.36 | $2.18M | 17,494 | Form 4 |
| 2026-01-07 | Devers Shannon L.EVP, Chief Human Resources Ofc | Saleplan | 2,101 | 85.36 | $179,341 | 17,494 | Form 4 |
| 2026-01-07 | Devers Shannon L.EVP, Chief Human Resources Ofc | Saleplan | 3,460 | 84.62 | $292,785 | 17,494 | Form 4 |
| 2026-01-07 | Devers Shannon L.EVP, Chief Human Resources Ofc | Saleplan | 3,829 | 84.62 | $324,010 | 17,494 | Form 4 |
| 2026-01-07 | Devers Shannon L.EVP, Chief Human Resources Ofc | Saleplan | 9,264 | 84.62 | $783,920 | 17,494 | Form 4 |
| 2026-01-02 | Swayze EricEVP Research | Saleplan | 5,125 | 78.57 | $402,671 | 30,453 | Form 4 |
| 2026-01-02 | Swayze EricEVP Research | Saleplan | 18,338 | 79.27 | $1.45M | 30,453 | Form 4 |
| 2025-12-01 | Wender Joseph HDirector | Saleplanindirect | 20,571 | 80.67 | $1.66M | 43,464 | Form 4 |
| 2025-12-01 | Wender Joseph HDirector | Saleplanindirect | 7,429 | 81.23 | $603,458 | 36,035 | Form 4 |
| 2025-11-25 | Devers Shannon L.EVP, Chief Human Resources Ofc | Saleplan | 16,777 | 80.91 | $1.36M | 17,494 | Form 4 |
| 2025-11-25 | Klein Joseph IIIDirector | Saleplanindirect | 4,000 | 80.00 | $320,000 | 0 | Form 4 |
| 2025-11-25 | Klein Joseph IIIDirector | Saleplanindirect | 4,000 | 80.00 | $320,000 | 0 | Form 4 |
| 2025-11-25 | Klein Joseph IIIDirector | Saleplanindirect | 4,000 | 80.00 | $320,000 | 0 | Form 4 |
| 2025-11-19 | Herman Joan eDirector | Sale | 12,000 | 72.13 | $865,560 | 46,086 | Form 4 |
| 2025-11-19 | Herman Joan eDirector | Sale | 32,000 | 72.13 | $2.31M | 46,086 | Form 4 |
| 2025-11-06 | Geary Richard SEVP, Chief Development Officer | Saleplan | 14,738 | 76.10 | $1.12M | 59,657 | Form 4 |
| 2025-11-06 | Geary Richard SEVP, Chief Development Officer | Saleplan | 18,300 | 75.42 | $1.38M | 59,657 | Form 4 |
| 2025-11-06 | Birchler BrianEVP, Corp and Development Ops | Saleplan | 8,000 | 76.17 | $609,360 | 48,826 | Form 4 |
| 2025-11-05 | Geary Richard SEVP, Chief Development Officer | Saleplan | 800 | 75.01 | $60,008 | 59,657 | Form 4 |
| 2025-11-05 | Geary Richard SEVP, Chief Development Officer | Saleplan | 801 | 75.01 | $60,083 | 59,657 | Form 4 |
| 2025-11-03 | Geary Richard SEVP, Chief Development Officer | Saleplan | 775 | 75.05 | $58,164 | 59,657 | Form 4/A |
| 2025-11-03 | Geary Richard SEVP, Chief Development Officer | Saleplan | 905 | 75.05 | $67,920 | 59,657 | Form 4/A |
| 2025-10-31 | Geary Richard SEVP, Chief Development Officer | Saleplan | 34,585 | 75.11 | $2.60M | 79,657 | Form 4 |
| 2025-10-31 | Geary Richard SEVP, Chief Development Officer | Saleplan | 34,664 | 75.11 | $2.60M | 79,657 | Form 4 |
| 2025-10-31 | Geary Richard SEVP, Chief Development Officer | Saleplan | 20,000 | 75.11 | $1.50M | 59,657 | Form 4 |
| 2025-10-31 | Loscalzo JosephDirector | Saleplan | 16,000 | 75.10 | $1.20M | 36,330 | Form 4 |
| 2025-10-31 | Wender Joseph HDirector | Saleplanindirect | 11,200 | 75.16 | $841,792 | 64,035 | Form 4 |
| 2025-10-30 | Wender Joseph HDirector | Saleplanindirect | 2,484 | 72.19 | $179,320 | 89,551 | Form 4 |
| 2025-10-30 | Wender Joseph HDirector | Saleplanindirect | 8,341 | 73.16 | $610,228 | 81,210 | Form 4 |
| 2025-10-30 | Wender Joseph HDirector | Saleplanindirect | 5,975 | 73.85 | $441,254 | 75,235 | Form 4 |
| 2025-10-16 | Devers Shannon L.EVP, Chief Human Resources Ofc | Saleplan | 1,263 | 73.62 | $92,982 | 17,494 | Form 4 |
| 2025-10-16 | Swayze EricEVP Research | Saleindirect | 53 | 73.62 | $3,902 | 256 | Form 4 |
| 2025-10-15 | Birchler BrianEVP, Corp and Development Ops | Saleplan | 12,425 | 72.23 | $897,458 | 56,826 | Form 4 |
| 2025-10-15 | Devers Shannon L.EVP, Chief Human Resources Ofc | Saleplan | 6,000 | 72.94 | $437,640 | 15,937 | Form 4 |
| 2025-10-15 | Parshall B LynneDirector | Saleplan | 5,000 | 71.74 | $358,700 | 61,344 | Form 4 |
| 2025-10-14 | Birchler BrianEVP, Corp and Development Ops | Saleplan | 11,475 | 72.03 | $826,544 | 56,826 | Form 4 |
| 2025-10-06 | Baroldi JosephEVP, Chief Business Officer | Saleplan | 1,625 | 69.37 | $112,726 | 30,301 | Form 4 |
| 2025-10-06 | Monia Brett PDirector, Chief Executive Officer | Saleplan | 437 | 69.26 | $30,267 | 179,572 | Form 4 |
| 2025-10-06 | O'Neil Patrick R.EVP CLO & General Counsel | Saleplan | 10,200 | 69.89 | $712,878 | 57,130 | Form 4 |
| 2025-10-06 | O'Neil Patrick R.EVP CLO & General Counsel | Saleplan | 3,241 | 69.27 | $224,504 | 53,889 | Form 4 |
| 2025-10-06 | Swayze EricEVP Research | Saleplan | 6,849 | 69.02 | $472,718 | 30,453 | Form 4 |
| 2025-10-02 | Baroldi JosephEVP, Chief Business Officer | Saleplan | 15,000 | 68.01 | $1.02M | 31,926 | Form 4 |
| 2025-10-02 | O'Neil Patrick R.EVP CLO & General Counsel | Saleplan | 30,203 | 67.69 | $2.04M | 57,130 | Form 4 |
| 2025-10-02 | O'Neil Patrick R.EVP CLO & General Counsel | Saleplan | 34,461 | 67.69 | $2.33M | 57,130 | Form 4 |
| 2025-10-02 | Swayze EricEVP Research | Saleplan | 12,972 | 66.23 | $859,136 | 37,302 | Form 4 |
| 2025-10-01 | Swayze EricEVP Research | Saleplan | 14,142 | 66.09 | $934,645 | 37,302 | Form 4 |
| 2025-10-01 | Wender Joseph HDirector | Saleplanindirect | 16,800 | 65.50 | $1.10M | 92,035 | Form 4 |
| 2025-09-30 | Hougen Elizabeth LEVP, Finance & CFO | Saleplan | 49,800 | 65.26 | $3.25M | 110,500 | Form 4 |
| 2025-09-30 | Geary Richard SEVP, Chief Development Officer | Saleplan | 57,900 | 65.24 | $3.78M | 79,657 | Form 4 |
| 2025-09-30 | O'Neil Patrick R.EVP CLO & General Counsel | Saleplan | 14,827 | 64.68 | $959,010 | 57,130 | Form 4 |
| 2025-09-29 | O'Neil Patrick R.EVP CLO & General Counsel | Saleplan | 10,473 | 64.54 | $675,927 | 57,130 | Form 4 |
| 2025-09-12 | O'Neil Patrick R.EVP CLO & General Counsel | Saleplan | 1,700 | 64.58 | $109,786 | 57,130 | Form 4 |
| 2025-09-09 | O'Neil Patrick R.EVP CLO & General Counsel | Saleplan | 20,000 | 64.56 | $1.29M | 57,130 | Form 4 |
| 2025-09-09 | O'Neil Patrick R.EVP CLO & General Counsel | Saleplan | 1,000 | 64.56 | $64,560 | 57,130 | Form 4 |
| 2025-09-09 | Baroldi JosephEVP, Chief Business Officer | Saleplan | 11,950 | 62.16 | $742,812 | 31,926 | Form 4 |
| 2025-09-05 | Bennett C FrankEVP, Chief Scientific Officer | Saleplan | 6,000 | 59.60 | $357,600 | 82,679 | Form 4 |
| 2025-09-05 | Baroldi JosephEVP, Chief Business Officer | Saleplan | 250 | 62.00 | $15,500 | 31,926 | Form 4 |
| 2025-09-03 | Schneider EugeneEVP, Chf Clinical Develop Ofcr | Saleplan | 12,455 | 60.46 | $753,029 | 58,710 | Form 4 |
| 2025-09-03 | Schneider EugeneEVP, Chf Clinical Develop Ofcr | Saleplan | 7,203 | 61.42 | $442,408 | 51,507 | Form 4 |
| 2025-09-03 | Loscalzo JosephDirector | Sale | 16,000 | 60.15 | $962,400 | 36,330 | Form 4 |
| 2025-09-03 | Bennett C FrankEVP, Chief Scientific Officer | Saleplan | 33,909 | 60.62 | $2.06M | 101,570 | Form 4 |
| 2025-09-03 | O'Neil Patrick R.EVP CLO & General Counsel | Saleplan | 65,475 | 60.89 | $3.99M | 5,655 | Form 4 |
| 2025-09-03 | O'Neil Patrick R.EVP CLO & General Counsel | Saleplan | 11,375 | 61.42 | $698,652 | 7,330 | Form 4 |
| 2025-09-03 | Baroldi JosephEVP, Chief Business Officer | Saleplan | 2,800 | 62.01 | $173,628 | 31,926 | Form 4 |
| 2025-09-03 | Baroldi JosephEVP, Chief Business Officer | Saleplan | 30,000 | 59.09 | $1.77M | 16,926 | Form 4 |
| 2025-09-03 | Wender Joseph HDirector | Saleplanindirect | 11,200 | 60.14 | $673,568 | 108,835 | Form 4 |
| 2025-09-03 | Devers Shannon L.EVP, Chief Human Resources Ofc | Saleplan | 3,162 | 61.02 | $192,945 | 15,009 | Form 4 |
| 2025-09-03 | Klein Joseph IIIDirector | Saleplanindirect | 28,000 | 60.00 | $1.68M | 0 | Form 4 |
| 2025-09-03 | Klein Joseph IIIDirector | Saleplanindirect | 28,000 | 60.00 | $1.68M | 0 | Form 4 |
| 2025-09-03 | Monia Brett PDirector, Chief Executive Officer | Sale | 16,615 | 59.12 | $982,279 | 266,294 | Form 4 |
| 2025-09-03 | Monia Brett PDirector, Chief Executive Officer | Sale | 127,500 | 60.13 | $7.67M | 180,824 | Form 4 |
| 2025-09-03 | Monia Brett PDirector, Chief Executive Officer | Sale | 59,699 | 61.06 | $3.65M | 180,009 | Form 4 |
| 2025-09-03 | Wender Joseph HDirector | Saleplanindirect | 11,200 | 60.14 | $673,568 | 108,835 | Form 4 |
| 2025-09-02 | Bennett C FrankEVP, Chief Scientific Officer | Saleplan | 5,000 | 49.14 | $245,700 | 88,679 | Form 4 |
| 2025-09-02 | O'Neil Patrick R.EVP CLO & General Counsel | Saleplan | 13,050 | 54.51 | $711,356 | 57,130 | Form 4 |
| 2025-09-02 | Wender Joseph HDirector | Saleplanindirect | 11,200 | 55.04 | $616,448 | 125,635 | Form 4 |
| 2025-09-02 | Wender Joseph HDirector | Saleplanindirect | 5,600 | 57.53 | $322,168 | 120,035 | Form 4 |
| 2025-09-02 | Geary Richard SEVP, Chief Development Officer | Saleplan | 10,000 | 50.37 | $503,700 | 79,657 | Form 4 |
| 2025-09-02 | Parshall B LynneDirector | Saleplan | 10,750 | 50.42 | $542,015 | 75,594 | Form 4 |
| 2025-09-02 | Parshall B LynneDirector | Saleplan | 9,250 | 51.49 | $476,282 | 66,344 | Form 4 |
| 2025-09-02 | Wender Joseph HDirector | Saleplanindirect | 11,200 | 55.04 | $616,448 | 125,635 | Form 4 |
| 2025-09-02 | Wender Joseph HDirector | Saleplanindirect | 5,600 | 57.53 | $322,168 | 120,035 | Form 4 |
| 2025-09-02 | Swayze EricEVP Research | Saleplan | 10,000 | 49.22 | $492,200 | 38,432 | Form 4 |
| 2025-09-02 | Swayze EricEVP Research | Saleplan | 1,130 | 53.68 | $60,658 | 37,302 | Form 4 |
| 2025-08-22 | Diaz Allene M.Director | Saleplan | 1,427 | 42.53 | $60,690 | 18,368 | Form 4 |
| 2025-08-18 | Bennett C FrankEVP, Chief Scientific Officer | Saleplan | 10,000 | 43.98 | $439,800 | 93,466 | Form 4 |
| 2025-08-06 | Parshall B LynneDirector | Saleplan | 4,600 | 41.87 | $192,602 | 86,744 | Form 4 |
| 2025-08-06 | Parshall B LynneDirector | Saleplan | 400 | 42.63 | $17,052 | 86,344 | Form 4 |
| 2025-08-05 | Geary Richard SEVP, Chief Development Officer | Saleplan | 10,000 | 42.86 | $428,600 | 89,492 | Form 4 |
| 2025-08-04 | Schneider EugeneEVP, Chf Clinical Develop Ofcr | Saleplan | 9,549 | 42.80 | $408,697 | 51,507 | Form 4 |
| 2025-07-30 | Monia Brett PDirector, Chief Executive Officer | Saleplan | 2,432 | 45.00 | $109,440 | 179,820 | Form 4 |
| 2025-07-11 | Monia Brett PDirector, Chief Executive Officer | Saleplan | 1,160 | 41.74 | $48,418 | 179,820 | Form 4 |
| 2025-05-01 | Hayden Michael RDirector | Buy | 15,000 | 31.86 | $477,900 | 50,219 | Form 4 |
| 2025-04-16 | Baroldi JosephEVP, Chief Business Officer | Sale | 3,928 | 28.40 | $111,555 | 31,926 | Form 4 |
| 2025-04-16 | Jenne KyleEVP, Chf GL Pdt Str Ofcr | Sale | 3,016 | 28.36 | $85,534 | 11,199 | Form 4 |
| 2025-04-16 | Birchler BrianEVP, Corp and Development Ops | Sale | 680 | 28.37 | $19,292 | 56,660 | Form 4 |
| 2025-03-11 | Monia Brett PDirector, Chief Executive Officer | Saleplan | 140 | 32.32 | $4,525 | 180,980 | Form 4 |
| 2025-02-20 | O'Neil Patrick R.EVP CLO & General Counsel | Saleplan | 1,207 | 32.35 | $39,046 | 56,245 | Form 4 |
| 2025-02-04 | Monia Brett PDirector, Chief Executive Officer | Saleplan | 38,843 | 31.65 | $1.23M | 180,683 | Form 4 |
| 2025-02-04 | O'Neil Patrick R.EVP CLO & General Counsel | Saleplan | 6,165 | 31.62 | $194,937 | 57,452 | Form 4 |
| 2025-01-31 | Bennett C FrankEVP, Chief Scientific Officer | Sale | 1,327 | 32.46 | $43,074 | 93,146 | Form 4 |
| 2025-01-31 | Geary Richard SEVP, Chief Development Officer | Sale | 1,406 | 32.40 | $45,554 | 99,077 | Form 4 |
| 2025-01-31 | Hougen Elizabeth LEVP, Finance & CFO | Sale | 1,523 | 32.44 | $49,406 | 110,500 | Form 4 |
| 2025-01-31 | Monia Brett PDirector, Chief Executive Officer | Sale | 13,242 | 32.45 | $429,703 | 219,526 | Form 4 |
| 2025-01-31 | O'Neil Patrick R.EVP CLO & General Counsel | Sale | 1,406 | 32.49 | $45,681 | 63,617 | Form 4 |
| 2025-01-31 | Schneider EugeneEVP, Chf Clinical Develop Ofcr | Sale | 1,484 | 32.20 | $47,785 | 61,056 | Form 4 |
| 2025-01-31 | Swayze EricEVP Research | Sale | 1,367 | 32.31 | $44,168 | 48,017 | Form 4 |
| 2025-01-16 | Baroldi JosephEVP, Chief Business Officer | Sale | 3,401 | 32.70 | $111,213 | 25,017 | Form 4 |
| 2025-01-16 | Baroldi JosephEVP, Chief Business Officer | Saleindirect | 1,029 | 32.70 | $33,648 | 3,071 | Form 4 |
| 2025-01-16 | Bennett C FrankEVP, Chief Scientific Officer | Sale | 6,752 | 32.90 | $222,141 | 90,866 | Form 4 |
| 2025-01-16 | Birchler BrianEVP, Corp and Development Ops | Sale | 5,400 | 32.70 | $176,580 | 55,051 | Form 4 |
| 2025-01-16 | Devers Shannon L.EVP, Chief Human Resources Ofc | Sale | 4,267 | 32.78 | $139,872 | 15,937 | Form 4 |
| 2025-01-16 | Geary Richard SEVP, Chief Development Officer | Sale | 7,072 | 32.86 | $232,386 | 96,663 | Form 4 |
| 2025-01-16 | Hougen Elizabeth LEVP, Finance & CFO | Sale | 8,870 | 32.81 | $291,025 | 107,885 | Form 4 |
| 2025-01-16 | Monia Brett PDirector, Chief Executive Officer | Sale | 33,445 | 32.63 | $1.09M | 207,396 | Form 4 |
| 2025-01-16 | O'Neil Patrick R.EVP CLO & General Counsel | Sale | 7,360 | 32.83 | $241,629 | 61,203 | Form 4 |
| 2025-01-16 | Schneider EugeneEVP, Chf Clinical Develop Ofcr | Sale | 6,523 | 32.79 | $213,889 | 58,508 | Form 4 |
| 2025-01-16 | Swayze EricEVP Research | Sale | 7,154 | 32.84 | $234,937 | 45,670 | Form 4 |
| 2025-01-16 | Swayze EricEVP Research | Saleindirect | 22 | 32.70 | $719 | 184 | Form 4 |
| 2024-12-23 | Hayden Michael RDirector | Buy | 2,500 | 36.20 | $90,500 | 32,719 | Form 4 |
| 2024-12-23 | Hayden Michael RDirector | Buy | 2,500 | 36.23 | $90,575 | 35,219 | Form 4 |
| 2024-11-12 | Loscalzo JosephDirector | Saleplan | 13,508 | 37.86 | $511,413 | 32,251 | Form 4 |
| 2024-11-12 | Monia Brett PDirector, Chief Executive Officer | Saleplan | 6,630 | 38.05 | $252,271 | 167,393 | Form 4 |
| 2024-11-12 | Swayze EricEVP Research | Saleplan | 1,194 | 37.92 | $45,276 | 33,713 | Form 4 |
Grants, exercises and other transactions
Pay, tax and paperwork rather than a choice to trade at the market price. Two years.
163 × option exercise22 × other15 × grant or award
Show them
| Date | Insider | What | Shares | Price | Holds after | Filing |
|---|---|---|---|---|---|---|
| 2026-08-31 | Birchler BrianEVP, Corp and Development Ops | Other J | +58 | 51.31 | 102,883 | Form 4 |
| 2026-08-31 | Monia Brett PDirector, Chief Executive Officer | Other J | +98 | 51.31 | 242,760 | Form 4 |
| 2026-08-31 | O'Neil Patrick R.EVP CLO & General Counsel | Other J | +63 | 51.31 | 59,205 | Form 4 |
| 2026-08-31 | Bennett C FrankEVP, Chief Scientific Officer | Other J | +110 | 51.31 | 60,128 | Form 4 |
| 2026-07-15 | Berthelsen Spencer RDirector | Option exercise M | +5,220 | – | 161,233 | Form 4 |
| 2026-07-15 | Herman Joan eDirector | Option exercise M | +5,220 | – | 51,306 | Form 4 |
| 2026-07-07 | Diaz Allene M.Director | Option exercise M | +10,111 | 47.11 | 13,922 | Form 4 |
| 2026-07-07 | Bennett C FrankEVP, Chief Scientific Officer | Other J | +15,000 | – | 15,000 | Form 4 |
| 2026-07-01 | Klein Joseph IIIDirector | Option exercise M | +11,518 | 39.94 | 22,532 | Form 4 |
| 2026-06-26 | Schneider EugeneEVP, Chf Clinical Develop Ofcr | Option exercise M | +26,000 | 60.89 | 103,114 | Form 4 |
| 2026-06-26 | Baroldi JosephEVP, Chief Business Officer | Option exercise M | +3,866 | 56.78 | 8,535 | Form 4 |
| 2026-06-26 | Baroldi JosephEVP, Chief Business Officer | Option exercise M | +1,769 | 32.60 | 10,304 | Form 4 |
| 2026-06-26 | Monia Brett PDirector, Chief Executive Officer | Option exercise M | +50,000 | 56.78 | 295,571 | Form 4 |
| 2026-06-25 | Monia Brett PDirector, Chief Executive Officer | Option exercise M | +21,072 | 32.60 | 266,643 | Form 4 |
| 2026-06-24 | Monia Brett PDirector, Chief Executive Officer | Option exercise M | +14,565 | 32.60 | 260,136 | Form 4 |
| 2026-06-15 | Berthelsen Spencer RDirector | Option exercise M | +8,000 | 24.42 | 164,013 | Form 4 |
| 2026-06-12 | Kordasiewicz Holly B.EVP, Chief Development Officer | Option exercise M | +7,951 | 60.89 | 30,409 | Form 4 |
| 2026-06-12 | Kordasiewicz Holly B.EVP, Chief Development Officer | Option exercise M | +21,000 | 60.89 | 51,409 | Form 4 |
| 2026-06-12 | Kordasiewicz Holly B.EVP, Chief Development Officer | Option exercise M | +12,000 | 32.60 | 63,409 | Form 4 |
| 2026-06-12 | Kordasiewicz Holly B.EVP, Chief Development Officer | Option exercise M | +19,895 | 56.78 | 83,304 | Form 4 |
| 2026-06-01 | Berthelsen Spencer RDirector | Option exercise M | +8,000 | 24.42 | 164,013 | Form 4 |
| 2026-05-14 | Monia Brett PDirector, Chief Executive Officer | Option exercise M | +3,220 | 32.60 | 245,882 | Form 4 |
| 2026-05-13 | Monia Brett PDirector, Chief Executive Officer | Option exercise M | +1,316 | 32.60 | 243,978 | Form 4 |
| 2026-05-04 | Loscalzo JosephDirector | Option exercise M | +10,968 | 38.06 | 47,298 | Form 4 |
| 2026-05-04 | Loscalzo JosephDirector | Option exercise M | +12,000 | 40.05 | 59,298 | Form 4 |
| 2026-05-04 | Loscalzo JosephDirector | Option exercise M | +10,321 | 41.08 | 69,619 | Form 4 |
| 2026-05-04 | Loscalzo JosephDirector | Option exercise M | +16,000 | 42.88 | 85,619 | Form 4 |
| 2026-05-04 | Loscalzo JosephDirector | Option exercise M | +12,000 | 60.20 | 97,619 | Form 4 |
| 2026-05-04 | Loscalzo JosephDirector | Option exercise M | +16,000 | 64.80 | 113,619 | Form 4 |
| 2026-05-01 | Klein Joseph IIIDirector | Option exercise M | +10,111 | 47.11 | 21,125 | Form 4 |
| 2026-04-15 | Baroldi JosephEVP, Chief Business Officer | Option exercise M | +10,837 | – | 52,154 | Form 4 |
| 2026-04-15 | Birchler BrianEVP, Corp and Development Ops | Option exercise M | +1,875 | – | 68,473 | Form 4 |
| 2026-04-15 | Jenne KyleEVP, Chf GL Pdt Str Ofcr | Option exercise M | +12,226 | – | 28,615 | Form 4 |
| 2026-04-01 | Klein Joseph IIIDirector | Option exercise M | +12,000 | 38.06 | 23,014 | Form 4 |
| 2026-04-01 | Klein Joseph IIIDirector | Option exercise M | +10,321 | 41.08 | 33,335 | Form 4 |
| 2026-03-16 | Hougen Elizabeth LEVP, Finance & CFO | Option exercise M | +60,299 | 60.89 | 193,180 | Form 4 |
| 2026-03-16 | Hougen Elizabeth LEVP, Finance & CFO | Option exercise M | +61,041 | 56.78 | 254,221 | Form 4 |
| 2026-03-16 | Hougen Elizabeth LEVP, Finance & CFO | Option exercise M | +33,118 | 32.60 | 287,339 | Form 4 |
| 2026-03-16 | Hougen Elizabeth LEVP, Finance & CFO | Option exercise M | +20,541 | 37.58 | 307,880 | Form 4 |
| 2026-03-10 | Jenne KyleEVP, Chf GL Pdt Str Ofcr | Option exercise M | +32,602 | 46.10 | 48,991 | Form 4 |
| 2026-03-10 | Jenne KyleEVP, Chf GL Pdt Str Ofcr | Option exercise M | +4,675 | 34.69 | 16,389 | Form 4 |
| 2026-03-10 | Monia Brett PDirector, Chief Executive Officer | Option exercise M | +34,103 | 60.89 | 276,765 | Form 4 |
| 2026-03-09 | Monia Brett PDirector, Chief Executive Officer | Option exercise M | +40,822 | 60.89 | 295,803 | Form 4 |
| 2026-03-09 | Monia Brett PDirector, Chief Executive Officer | Option exercise M | +73,529 | 60.89 | 369,332 | Form 4 |
| 2026-03-04 | Baroldi JosephEVP, Chief Business Officer | Option exercise M | +238 | 56.78 | 4,585 | Form 4 |
| 2026-03-04 | Baroldi JosephEVP, Chief Business Officer | Option exercise M | +201 | 32.60 | 4,548 | Form 4 |
| 2026-03-04 | Loscalzo JosephDirector | Option exercise M | +200 | 38.06 | 36,530 | Form 4 |
| 2026-03-03 | Baroldi JosephEVP, Chief Business Officer | Option exercise M | +820 | 56.78 | 5,592 | Form 4 |
| 2026-03-03 | Baroldi JosephEVP, Chief Business Officer | Option exercise M | +879 | 32.60 | 6,471 | Form 4 |
| 2026-03-03 | Bennett C FrankEVP, Chief Scientific Officer | Option exercise M | +16,463 | 32.60 | 117,017 | Form 4 |
| 2026-03-03 | Bennett C FrankEVP, Chief Scientific Officer | Option exercise M | +48,626 | 60.89 | 165,643 | Form 4 |
| 2026-03-03 | Devers Shannon L.EVP, Chief Human Resources Ofc | Option exercise M | +3,510 | 37.58 | 26,051 | Form 4 |
| 2026-03-03 | Devers Shannon L.EVP, Chief Human Resources Ofc | Option exercise M | +3,760 | 40.85 | 29,811 | Form 4 |
| 2026-03-03 | Devers Shannon L.EVP, Chief Human Resources Ofc | Option exercise M | +5,500 | 34.69 | 35,311 | Form 4 |
| 2026-03-03 | Devers Shannon L.EVP, Chief Human Resources Ofc | Option exercise M | +6,951 | 32.60 | 42,262 | Form 4 |
| 2026-03-03 | Devers Shannon L.EVP, Chief Human Resources Ofc | Option exercise M | +385 | 52.87 | 42,647 | Form 4 |
| 2026-03-03 | Diaz Allene M.Director | Option exercise M | +10,321 | 41.08 | 28,689 | Form 4 |
| 2026-03-03 | Diaz Allene M.Director | Option exercise M | +12,000 | 38.06 | 40,689 | Form 4 |
| 2026-03-03 | Diaz Allene M.Director | Option exercise M | +18,000 | 40.05 | 58,689 | Form 4 |
| 2026-03-03 | Klein Joseph IIIDirector | Option exercise M | +12,000 | 40.05 | 28,346 | Form 4 |
| 2026-03-03 | Klein Joseph IIIDirector | Option exercise M | +4,000 | 42.88 | 32,346 | Form 4 |
| 2026-03-03 | Loscalzo JosephDirector | Option exercise M | +832 | 38.06 | 37,162 | Form 4 |
| 2026-02-27 | Bennett C FrankEVP, Chief Scientific Officer | Other J | +261 | 48.87 | 100,554 | Form 4 |
| 2026-02-27 | Birchler BrianEVP, Corp and Development Ops | Other J | +351 | 48.87 | 66,598 | Form 4 |
| 2026-02-27 | Monia Brett PDirector, Chief Executive Officer | Other J | +484 | 48.87 | 254,981 | Form 4 |
| 2026-02-27 | O'Neil Patrick R.EVP CLO & General Counsel | Other J | +376 | 48.87 | 72,359 | Form 4 |
| 2026-02-27 | Swayze EricEVP Research | Other J | +256 | 48.87 | 32,361 | Form 4 |
| 2026-02-02 | Bennett C FrankEVP, Chief Scientific Officer | Other J | −0 | – | 100,293 | Form 4/A |
| 2026-02-02 | Bennett C FrankEVP, Chief Scientific Officer | Option exercise M | +48,626 | 60.89 | 128,919 | Form 4 |
| 2026-02-02 | Bennett C FrankEVP, Chief Scientific Officer | Option exercise M | +16,463 | 32.60 | 96,756 | Form 4 |
| 2026-01-29 | Baroldi JosephEVP, Chief Business Officer | Grant or award A | +10,278 | – | 50,709 | Form 4 |
| 2026-01-29 | Bennett C FrankEVP, Chief Scientific Officer | Grant or award A | +11,421 | – | 106,178 | Form 4 |
| 2026-01-29 | Birchler BrianEVP, Corp and Development Ops | Grant or award A | +11,991 | – | 72,426 | Form 4 |
| 2026-01-29 | Hougen Elizabeth LEVP, Finance & CFO | Grant or award A | +13,562 | – | 139,869 | Form 4 |
| 2026-01-29 | Monia Brett PDirector, Chief Executive Officer | Grant or award A | +122,214 | – | 346,897 | Form 4 |
| 2026-01-29 | O'Neil Patrick R.EVP CLO & General Counsel | Grant or award A | +11,991 | – | 78,162 | Form 4 |
| 2026-01-29 | Schneider EugeneEVP, Chf Clinical Develop Ofcr | Grant or award A | +11,991 | – | 75,881 | Form 4 |
| 2026-01-29 | Swayze EricEVP Research | Grant or award A | +11,991 | – | 53,926 | Form 4 |
| 2026-01-15 | Baroldi JosephEVP, Chief Business Officer | Option exercise M | +17,037 | – | 47,338 | Form 4 |
| 2026-01-15 | Baroldi JosephEVP, Chief Business Officer | Option exercise M | +2,850 | – | 5,921 | Form 4 |
| 2026-01-15 | Bennett C FrankEVP, Chief Scientific Officer | Option exercise M | +21,055 | – | 103,734 | Form 4 |
| 2026-01-15 | Birchler BrianEVP, Corp and Development Ops | Option exercise M | +20,089 | – | 68,915 | Form 4 |
| 2026-01-15 | Devers Shannon L.EVP, Chief Human Resources Ofc | Option exercise M | +17,377 | – | 34,871 | Form 4 |
| 2026-01-15 | Hougen Elizabeth LEVP, Finance & CFO | Option exercise M | +28,729 | – | 139,229 | Form 4 |
| 2026-01-15 | Jenne KyleEVP, Chf GL Pdt Str Ofcr | Option exercise M | +7,013 | – | 18,212 | Form 4 |
| 2026-01-15 | Kordasiewicz Holly B.EVP, Chief Development Officer | Option exercise M | +11,119 | – | 18,859 | Form 4 |
| 2026-01-15 | Monia Brett PDirector, Chief Executive Officer | Option exercise M | +89,145 | – | 268,717 | Form 4 |
| 2026-01-15 | O'Neil Patrick R.EVP CLO & General Counsel | Option exercise M | +21,473 | – | 75,362 | Form 4 |
| 2026-01-15 | Schneider EugeneEVP, Chf Clinical Develop Ofcr | Option exercise M | +21,685 | – | 73,192 | Form 4 |
| 2026-01-15 | Swayze EricEVP Research | Option exercise M | +21,366 | – | 51,819 | Form 4 |
| 2026-01-15 | Swayze EricEVP Research | Option exercise M | +111 | – | 367 | Form 4 |
| 2026-01-15 | Yang Michael J.Director | Option exercise M | +1,930 | – | 7,940 | Form 4 |
| 2026-01-07 | Devers Shannon L.EVP, Chief Human Resources Ofc | Option exercise M | +25,545 | 56.78 | 43,039 | Form 4 |
| 2026-01-07 | Devers Shannon L.EVP, Chief Human Resources Ofc | Option exercise M | +2,101 | 32.60 | 19,595 | Form 4 |
| 2026-01-07 | Devers Shannon L.EVP, Chief Human Resources Ofc | Option exercise M | +3,460 | 32.60 | 20,954 | Form 4 |
| 2026-01-07 | Devers Shannon L.EVP, Chief Human Resources Ofc | Option exercise M | +3,829 | 37.58 | 21,323 | Form 4 |
| 2026-01-07 | Devers Shannon L.EVP, Chief Human Resources Ofc | Option exercise M | +9,264 | 52.87 | 26,758 | Form 4 |
| 2026-01-02 | Swayze EricEVP Research | Option exercise M | +5,125 | 60.89 | 35,578 | Form 4 |
| 2026-01-02 | Swayze EricEVP Research | Option exercise M | +18,338 | 60.89 | 48,791 | Form 4 |
| 2025-11-25 | Devers Shannon L.EVP, Chief Human Resources Ofc | Option exercise M | +16,777 | 53.77 | 34,271 | Form 4 |
| 2025-11-25 | Klein Joseph IIIDirector | Option exercise M | +4,000 | – | 4,000 | Form 4 |
| 2025-11-25 | Klein Joseph IIIDirector | Option exercise M | +4,000 | – | 4,000 | Form 4 |
| 2025-11-25 | Klein Joseph IIIDirector | Option exercise M | +4,000 | – | 4,000 | Form 4 |
| 2025-11-19 | Herman Joan eDirector | Option exercise M | +12,000 | 40.05 | 58,086 | Form 4 |
| 2025-11-19 | Herman Joan eDirector | Option exercise M | +32,000 | 63.90 | 78,086 | Form 4 |
| 2025-11-18 | Wender Joseph HDirector | Option exercise M | +16,000 | 24.42 | 16,000 | Form 4 |
| 2025-11-06 | Geary Richard SEVP, Chief Development Officer | Option exercise M | +14,738 | 56.78 | 74,395 | Form 4 |
| 2025-11-06 | Geary Richard SEVP, Chief Development Officer | Option exercise M | +18,300 | 60.89 | 77,957 | Form 4 |
| 2025-11-05 | Geary Richard SEVP, Chief Development Officer | Option exercise M | +800 | 56.78 | 60,457 | Form 4 |
| 2025-11-05 | Geary Richard SEVP, Chief Development Officer | Option exercise M | +801 | 60.89 | 60,458 | Form 4 |
| 2025-11-03 | Geary Richard SEVP, Chief Development Officer | Option exercise M | +775 | 60.89 | 60,432 | Form 4/A |
| 2025-11-03 | Geary Richard SEVP, Chief Development Officer | Option exercise M | +905 | 56.78 | 60,562 | Form 4/A |
| 2025-10-31 | Geary Richard SEVP, Chief Development Officer | Option exercise M | +34,585 | 60.89 | 114,242 | Form 4 |
| 2025-10-31 | Geary Richard SEVP, Chief Development Officer | Option exercise M | +34,664 | 56.78 | 114,321 | Form 4 |
| 2025-10-31 | Loscalzo JosephDirector | Option exercise M | +16,000 | 52.22 | 52,330 | Form 4 |
| 2025-10-15 | Birchler BrianEVP, Corp and Development Ops | Option exercise M | +12,425 | 53.77 | 69,251 | Form 4 |
| 2025-10-15 | Devers Shannon L.EVP, Chief Human Resources Ofc | Option exercise M | +6,000 | 48.51 | 21,937 | Form 4 |
| 2025-10-15 | Devers Shannon L.EVP, Chief Human Resources Ofc | Option exercise M | +2,820 | – | 18,757 | Form 4 |
| 2025-10-15 | Swayze EricEVP Research | Option exercise M | +125 | – | 309 | Form 4 |
| 2025-10-14 | Birchler BrianEVP, Corp and Development Ops | Option exercise M | +11,475 | 53.77 | 68,301 | Form 4 |
| 2025-10-06 | O'Neil Patrick R.EVP CLO & General Counsel | Option exercise M | +10,200 | 52.87 | 67,330 | Form 4 |
| 2025-10-02 | Baroldi JosephEVP, Chief Business Officer | Option exercise M | +15,000 | 31.80 | 46,926 | Form 4 |
| 2025-10-02 | O'Neil Patrick R.EVP CLO & General Counsel | Option exercise M | +30,203 | 56.78 | 87,333 | Form 4 |
| 2025-10-02 | O'Neil Patrick R.EVP CLO & General Counsel | Option exercise M | +34,461 | 60.89 | 91,591 | Form 4 |
| 2025-10-02 | Swayze EricEVP Research | Option exercise M | +12,972 | 53.77 | 50,274 | Form 4 |
| 2025-10-01 | Swayze EricEVP Research | Option exercise M | +14,142 | 53.77 | 51,444 | Form 4 |
| 2025-09-30 | Hougen Elizabeth LEVP, Finance & CFO | Option exercise M | +49,800 | 53.77 | 160,300 | Form 4 |
| 2025-09-30 | Geary Richard SEVP, Chief Development Officer | Option exercise M | +57,900 | 53.77 | 137,557 | Form 4 |
| 2025-09-30 | O'Neil Patrick R.EVP CLO & General Counsel | Option exercise M | +14,827 | 56.78 | 71,957 | Form 4 |
| 2025-09-29 | O'Neil Patrick R.EVP CLO & General Counsel | Option exercise M | +10,473 | 56.78 | 67,603 | Form 4 |
| 2025-09-12 | O'Neil Patrick R.EVP CLO & General Counsel | Option exercise M | +1,700 | 56.78 | 58,830 | Form 4 |
| 2025-09-09 | O'Neil Patrick R.EVP CLO & General Counsel | Option exercise M | +20,000 | 60.89 | 77,130 | Form 4 |
| 2025-09-09 | O'Neil Patrick R.EVP CLO & General Counsel | Option exercise M | +1,000 | 56.78 | 58,130 | Form 4 |
| 2025-09-09 | Baroldi JosephEVP, Chief Business Officer | Option exercise M | +11,950 | 31.80 | 43,876 | Form 4 |
| 2025-09-05 | Baroldi JosephEVP, Chief Business Officer | Option exercise M | +250 | 31.80 | 32,176 | Form 4 |
| 2025-09-03 | Schneider EugeneEVP, Chf Clinical Develop Ofcr | Option exercise M | +19,658 | 53.77 | 71,165 | Form 4 |
| 2025-09-03 | Loscalzo JosephDirector | Option exercise M | +16,000 | 24.42 | 52,330 | Form 4 |
| 2025-09-03 | Bennett C FrankEVP, Chief Scientific Officer | Option exercise M | +46,800 | 53.77 | 135,479 | Form 4 |
| 2025-09-03 | Bennett C FrankEVP, Chief Scientific Officer | Option exercise M | −12,891 | 61.50 | 88,679 | Form 4 |
| 2025-09-03 | O'Neil Patrick R.EVP CLO & General Counsel | Option exercise M | +14,000 | 37.58 | 71,130 | Form 4 |
| 2025-09-03 | O'Neil Patrick R.EVP CLO & General Counsel | Option exercise M | +13,050 | 32.60 | 18,705 | Form 4 |
| 2025-09-03 | O'Neil Patrick R.EVP CLO & General Counsel | Option exercise M | +49,800 | 53.77 | 57,130 | Form 4 |
| 2025-09-03 | Baroldi JosephEVP, Chief Business Officer | Option exercise M | +2,800 | 31.80 | 34,726 | Form 4 |
| 2025-09-03 | Baroldi JosephEVP, Chief Business Officer | Option exercise M | +15,000 | 31.80 | 46,926 | Form 4 |
| 2025-09-03 | Baroldi JosephEVP, Chief Business Officer | Option exercise M | +15,000 | 31.80 | 31,926 | Form 4 |
| 2025-09-03 | Devers Shannon L.EVP, Chief Human Resources Ofc | Option exercise M | +2,234 | 37.58 | 18,171 | Form 4 |
| 2025-09-03 | Devers Shannon L.EVP, Chief Human Resources Ofc | Option exercise M | +928 | 32.60 | 15,937 | Form 4 |
| 2025-09-03 | Klein Joseph IIIDirector | Option exercise M | +16,000 | – | 16,000 | Form 4 |
| 2025-09-03 | Klein Joseph IIIDirector | Option exercise M | +12,000 | – | 28,000 | Form 4 |
| 2025-09-03 | Klein Joseph IIIDirector | Option exercise M | +16,000 | – | 16,000 | Form 4 |
| 2025-09-03 | Klein Joseph IIIDirector | Option exercise M | +12,000 | – | 28,000 | Form 4 |
| 2025-09-03 | Monia Brett PDirector, Chief Executive Officer | Option exercise M | +102,900 | 53.77 | 282,909 | Form 4 |
| 2025-09-03 | Monia Brett PDirector, Chief Executive Officer | Option exercise M | +42,030 | 37.58 | 308,324 | Form 4 |
| 2025-09-03 | Monia Brett PDirector, Chief Executive Officer | Option exercise M | +31,316 | 32.60 | 212,140 | Form 4 |
| 2025-09-03 | Monia Brett PDirector, Chief Executive Officer | Option exercise M | +27,568 | 32.60 | 239,708 | Form 4 |
| 2025-09-02 | O'Neil Patrick R.EVP CLO & General Counsel | Option exercise M | +13,050 | 32.60 | 70,180 | Form 4 |
| 2025-08-29 | Birchler BrianEVP, Corp and Development Ops | Other J | +166 | 27.71 | 56,826 | Form 4 |
| 2025-08-29 | Bennett C FrankEVP, Chief Scientific Officer | Other J | +213 | 27.71 | 93,679 | Form 4 |
| 2025-08-29 | Geary Richard SEVP, Chief Development Officer | Other J | +165 | 27.71 | 89,657 | Form 4 |
| 2025-08-29 | Monia Brett PDirector, Chief Executive Officer | Other J | +189 | 27.71 | 180,009 | Form 4 |
| 2025-08-29 | O'Neil Patrick R.EVP CLO & General Counsel | Other J | +331 | 27.71 | 57,130 | Form 4 |
| 2025-08-18 | Bennett C FrankEVP, Chief Scientific Officer | Option exercise M | +10,000 | 32.60 | 103,466 | Form 4 |
| 2025-07-30 | Monia Brett PDirector, Chief Executive Officer | Option exercise M | +2,432 | 32.60 | 182,252 | Form 4 |
| 2025-07-15 | Berthelsen Spencer RDirector | Option exercise M | +4,079 | – | 156,013 | Form 4 |
| 2025-07-15 | Diaz Allene M.Director | Option exercise M | +4,079 | – | 19,795 | Form 4 |
| 2025-07-15 | Hayden Michael RDirector | Option exercise M | +4,079 | – | 54,298 | Form 4 |
| 2025-07-15 | Herman Joan eDirector | Option exercise M | +4,079 | – | 46,086 | Form 4 |
| 2025-07-15 | Parshall B LynneDirector | Option exercise M | +4,079 | – | 91,344 | Form 4 |
| 2025-07-15 | Wender Joseph HDirector | Option exercise M | +4,079 | – | 136,835 | Form 4 |
| 2025-07-15 | Yang Michael J.Director | Option exercise M | +4,079 | – | 6,010 | Form 4 |
| 2025-07-15 | Loscalzo JosephDirector | Option exercise M | +4,079 | – | 36,330 | Form 4 |
| 2025-04-15 | Baroldi JosephEVP, Chief Business Officer | Option exercise M | +10,837 | – | 35,854 | Form 4 |
| 2025-04-15 | Jenne KyleEVP, Chf GL Pdt Str Ofcr | Option exercise M | +12,226 | – | 14,215 | Form 4 |
| 2025-04-15 | Birchler BrianEVP, Corp and Development Ops | Option exercise M | +1,875 | – | 57,340 | Form 4 |
| 2025-02-28 | Bennett C FrankEVP, Chief Scientific Officer | Other J | +320 | 28.21 | 93,466 | Form 4 |
| 2025-02-28 | Birchler BrianEVP, Corp and Development Ops | Other J | +414 | 28.21 | 55,465 | Form 4 |
| 2025-02-28 | Geary Richard SEVP, Chief Development Officer | Other J | +415 | 28.21 | 99,492 | Form 4 |
| 2025-02-28 | Monia Brett PDirector, Chief Executive Officer | Other J | +437 | 28.21 | 181,120 | Form 4 |
| 2025-02-28 | O'Neil Patrick R.EVP CLO & General Counsel | Other J | +554 | 28.21 | 56,799 | Form 4 |
| 2025-02-28 | Swayze EricEVP Research | Other J | +415 | 28.21 | 48,432 | Form 4 |
| 2025-01-30 | Bennett C FrankEVP, Chief Scientific Officer | Grant or award A | +3,607 | – | 94,473 | Form 4 |
| 2025-01-30 | Geary Richard SEVP, Chief Development Officer | Grant or award A | +3,820 | – | 100,483 | Form 4 |
| 2025-01-30 | Hougen Elizabeth LEVP, Finance & CFO | Grant or award A | +4,138 | – | 112,023 | Form 4 |
| 2025-01-30 | Monia Brett PDirector, Chief Executive Officer | Grant or award A | +25,372 | – | 232,768 | Form 4 |
| 2025-01-30 | O'Neil Patrick R.EVP CLO & General Counsel | Grant or award A | +3,820 | – | 65,023 | Form 4 |
| 2025-01-30 | Schneider EugeneEVP, Chf Clinical Develop Ofcr | Grant or award A | +4,032 | – | 62,540 | Form 4 |
| 2025-01-30 | Swayze EricEVP Research | Grant or award A | +3,714 | – | 49,384 | Form 4 |
| 2025-01-15 | Baroldi JosephEVP, Chief Business Officer | Option exercise M | +8,787 | – | 28,418 | Form 4 |
| 2025-01-15 | Baroldi JosephEVP, Chief Business Officer | Option exercise M | +2,460 | – | 4,100 | Form 4 |
| 2025-01-15 | Bennett C FrankEVP, Chief Scientific Officer | Option exercise M | +18,011 | – | 97,618 | Form 4 |
| 2025-01-15 | Birchler BrianEVP, Corp and Development Ops | Option exercise M | +14,283 | – | 60,451 | Form 4 |
| 2025-01-15 | Devers Shannon L.EVP, Chief Human Resources Ofc | Option exercise M | +12,295 | – | 20,204 | Form 4 |
| 2025-01-15 | Geary Richard SEVP, Chief Development Officer | Option exercise M | +18,901 | – | 103,735 | Form 4 |
| 2025-01-15 | Hougen Elizabeth LEVP, Finance & CFO | Option exercise M | +23,887 | – | 116,755 | Form 4 |
| 2025-01-15 | Monia Brett PDirector, Chief Executive Officer | Option exercise M | +73,448 | – | 240,841 | Form 4 |
| 2025-01-15 | O'Neil Patrick R.EVP CLO & General Counsel | Option exercise M | +19,690 | – | 68,563 | Form 4 |
| 2025-01-15 | Schneider EugeneEVP, Chf Clinical Develop Ofcr | Option exercise M | +17,372 | – | 65,031 | Form 4 |
| 2025-01-15 | Swayze EricEVP Research | Option exercise M | +19,111 | – | 52,824 | Form 4 |
| 2025-01-15 | Swayze EricEVP Research | Option exercise M | +49 | – | 206 | Form 4 |
| 2025-01-15 | Yang Michael J.Director | Option exercise M | +1,931 | – | 1,931 | Form 4 |
How to read it
- Buy, sale
- Code P and S on the form: shares bought or sold in the market, at the market price. The other codes are mostly pay (a grant, an option exercised) or tax (shares the company withheld), and say little about what the insider thinks of the price.
- Plan
- A sale or purchase under a Rule 10b5-1 plan, set up in advance and running on its own schedule. Since April 2023 the form has a box for it. Much executive selling is planned and says more about diversifying than about the company.
- Holds after
- The shares the insider still held after the trade, in the form the trade was in (directly, or indirectly through a trust or a fund).
- Value
- Shares times the price the form reports, which is often an average over several fills on the day.
Read from the SEC's own quarterly data sets of Forms 3, 4 and 5, and from each day's filings since the last one. A correcting amendment replaces the lines it restates. Every row links to its filing. None of this is advice: insiders sell for many reasons, and buy for fewer.