INSMED Inc (INSM) · Insider trading
What INSMED's directors, officers and largest holders bought and sold themselves, from the Form 4 each of them files with the SEC within two business days of a trade. Open-market purchases and sales first: those are the trades somebody chose to make at the market price.
Bought, 12 months
$0
0 insiders, 0 trades
Sold, 12 months
$167.12M
10 insiders, 56% under a plan
Net, 12 months
−$167.12M
bought less sold
Latest filing
2026-09-11
filings read to 2026-10-19
Who traded, two years
| Insider | Bought | Sold | Trades | Last trade | Holds after |
|---|---|---|---|---|---|
| Lewis WilliamDirector, Chair and CEO | – | $78.60M | 168 | 2026-07-23 | 264,930 |
| Flammer Martina M.d.Chief Medical Officer | – | $63.39M | 64 | 2026-08-06 | 78,764 |
| Adsett RogerChief Operating Officer | – | $61.04M | 27 | 2026-08-10 | 98,744 |
| Schaeffer Orlov S NicoleChief People Strategy Officer | – | $56.47M | 32 | 2026-01-02 | 98,014 |
| Bonstein SaraChief Financial Officer | – | $31.14M | 29 | 2026-06-03 | 69,082 |
| Smith Michael AlexanderChief Legal Officer | – | $21.97M | 38 | 2026-06-22 | 37,648 |
| Lee LeoDirector | – | $14.69M | 5 | 2025-11-17 | 126,465 |
| Sharoky Melvin MDDirector | – | $8.70M | 5 | 2026-08-17 | – |
| Brennan David RDirector | – | $3.10M | 1 | 2026-09-09 | 39,238 |
| Anderson Elizabeth MDirector | – | $2.98M | 2 | 2025-11-24 | 58,729 |
| Wise John DraytonChief Commercial Officer | – | $1.54M | 6 | 2025-02-07 | 133,015 |
| McGirr David W JDirector | – | $451,535 | 2 | 2025-06-04 | 97,723 |
| Desjardins ClarissaDirector | $201,694 | – | 2 | 2025-05-21 | – |
Open-market purchases and sales
Newest first. “Plan” marks a trade made under a 10b5-1 plan set up in advance.
| Date | Insider | Trade | Shares | Price | Value | Holds after | Filing |
|---|---|---|---|---|---|---|---|
| 2026-09-09 | Brennan David RDirector | Sale | 25,000 | 124.00 | $3.10M | 39,238 | Form 4 |
| 2026-08-17 | Sharoky Melvin MDDirector | Saleindirect | 5,000 | 127.53 | $637,650 | 0 | Form 4 |
| 2026-08-10 | Adsett RogerChief Operating Officer | Sale | 239,850 | 133.27 | $31.96M | 98,744 | Form 4 |
| 2026-08-06 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 8,895 | 127.00 | $1.13M | 78,764 | Form 4 |
| 2026-08-06 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 18,278 | 129.40 | $2.37M | 60,486 | Form 4 |
| 2026-07-23 | Lewis WilliamDirector, Chair and CEO | Saleplan | 4,828 | 105.62 | $509,933 | 264,930 | Form 4 |
| 2026-07-23 | Lewis WilliamDirector, Chair and CEO | Saleplan | 5,872 | 106.43 | $624,957 | 259,058 | Form 4 |
| 2026-07-09 | Lewis WilliamDirector, Chair and CEO | Saleplan | 5,005 | 116.55 | $583,333 | 264,752 | Form 4 |
| 2026-07-09 | Lewis WilliamDirector, Chair and CEO | Saleplan | 2,335 | 117.62 | $274,643 | 262,417 | Form 4 |
| 2026-07-09 | Lewis WilliamDirector, Chair and CEO | Saleplan | 3,359 | 118.52 | $398,109 | 259,058 | Form 4 |
| 2026-07-06 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 4,854 | 109.02 | $529,183 | 67,934 | Form 4 |
| 2026-07-06 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 7,448 | 110.60 | $823,749 | 60,486 | Form 4 |
| 2026-06-25 | Lewis WilliamDirector, Chair and CEO | Saleplan | 12,091 | 102.34 | $1.24M | 268,224 | Form 4 |
| 2026-06-25 | Lewis WilliamDirector, Chair and CEO | Saleplan | 1,836 | 103.10 | $189,292 | 266,388 | Form 4 |
| 2026-06-25 | Lewis WilliamDirector, Chair and CEO | Saleplan | 3,723 | 104.28 | $388,234 | 262,665 | Form 4 |
| 2026-06-25 | Lewis WilliamDirector, Chair and CEO | Saleplan | 2,456 | 105.27 | $258,543 | 260,209 | Form 4 |
| 2026-06-25 | Lewis WilliamDirector, Chair and CEO | Saleplan | 1,292 | 106.27 | $137,301 | 258,917 | Form 4 |
| 2026-06-22 | Smith Michael AlexanderChief Legal Officer | Saleplan | 1,806 | 95.82 | $173,051 | 37,648 | Form 4 |
| 2026-06-08 | Lewis WilliamDirector, Chair and CEO | Saleplan | 6,515 | 94.03 | $612,605 | 258,917 | Form 4 |
| 2026-06-05 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 1,858 | 103.78 | $192,823 | 60,486 | Form 4 |
| 2026-06-03 | Lewis WilliamDirector, Chair and CEO | Sale | 7,605 | 102.27 | $777,763 | 265,432 | Form 4 |
| 2026-06-03 | Bonstein SaraChief Financial Officer | Sale | 2,404 | 102.27 | $245,857 | 69,082 | Form 4 |
| 2026-06-03 | Adsett RogerChief Operating Officer | Sale | 2,370 | 102.27 | $242,380 | 98,603 | Form 4 |
| 2026-06-03 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 2,566 | 102.27 | $262,425 | 62,344 | Form 4 |
| 2026-06-03 | Smith Michael AlexanderChief Legal Officer | Sale | 2,159 | 102.27 | $220,801 | 39,454 | Form 4 |
| 2026-05-22 | Smith Michael AlexanderChief Legal Officer | Saleplan | 6,149 | 108.47 | $666,982 | 41,613 | Form 4 |
| 2026-05-18 | Lewis WilliamDirector, Chair and CEO | Saleplan | 5,753 | 105.32 | $605,906 | 292,848 | Form 4 |
| 2026-05-18 | Lewis WilliamDirector, Chair and CEO | Saleplan | 11,836 | 106.39 | $1.26M | 281,012 | Form 4 |
| 2026-05-18 | Lewis WilliamDirector, Chair and CEO | Saleplan | 7,975 | 106.97 | $853,086 | 273,037 | Form 4 |
| 2026-05-14 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 10,479 | 117.54 | $1.23M | 64,910 | Form 4 |
| 2026-05-13 | Lewis WilliamDirector, Chair and CEO | Sale | 13,283 | 116.18 | $1.54M | 287,902 | Form 4 |
| 2026-05-13 | Bonstein SaraChief Financial Officer | Sale | 8,272 | 116.18 | $961,041 | 71,486 | Form 4 |
| 2026-05-13 | Adsett RogerChief Operating Officer | Sale | 5,837 | 116.18 | $678,143 | 100,973 | Form 4 |
| 2026-05-13 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 4,470 | 112.76 | $504,037 | 78,773 | Form 4 |
| 2026-05-13 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 3,384 | 116.18 | $393,153 | 75,389 | Form 4 |
| 2026-05-13 | Smith Michael AlexanderChief Legal Officer | Sale | 4,109 | 116.18 | $477,384 | 47,762 | Form 4 |
| 2026-05-11 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 12,119 | 100.35 | $1.22M | 84,073 | Form 4 |
| 2026-05-11 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 830 | 101.18 | $83,979 | 83,243 | Form 4 |
| 2026-05-04 | Lewis WilliamDirector, Chair and CEO | Saleplan | 433 | 134.18 | $58,100 | 311,451 | Form 4 |
| 2026-05-04 | Lewis WilliamDirector, Chair and CEO | Saleplan | 599 | 135.18 | $80,973 | 310,852 | Form 4 |
341 more
| 2026-05-04 | Lewis WilliamDirector, Chair and CEO | Saleplan | 5,318 | 137.01 | $728,619 | 305,534 | Form 4 |
| 2026-05-04 | Lewis WilliamDirector, Chair and CEO | Saleplan | 2,721 | 137.86 | $375,117 | 302,813 | Form 4 |
| 2026-05-04 | Lewis WilliamDirector, Chair and CEO | Saleplan | 1,247 | 139.09 | $173,445 | 301,566 | Form 4 |
| 2026-05-04 | Lewis WilliamDirector, Chair and CEO | Saleplan | 381 | 139.60 | $53,188 | 301,185 | Form 4 |
| 2026-04-16 | Lewis WilliamDirector, Chair and CEO | Saleplan | 2,246 | 142.99 | $321,156 | 309,638 | Form 4 |
| 2026-04-16 | Lewis WilliamDirector, Chair and CEO | Saleplan | 5,373 | 143.81 | $772,691 | 304,265 | Form 4 |
| 2026-04-16 | Lewis WilliamDirector, Chair and CEO | Saleplan | 2,255 | 144.66 | $326,208 | 302,010 | Form 4 |
| 2026-04-16 | Lewis WilliamDirector, Chair and CEO | Saleplan | 825 | 145.79 | $120,277 | 301,185 | Form 4 |
| 2026-04-06 | Lewis WilliamDirector, Chair and CEO | Saleplan | 787 | 161.73 | $127,282 | 311,097 | Form 4 |
| 2026-04-06 | Lewis WilliamDirector, Chair and CEO | Saleplan | 8,478 | 163.23 | $1.38M | 302,619 | Form 4 |
| 2026-04-06 | Lewis WilliamDirector, Chair and CEO | Saleplan | 1,434 | 164.01 | $235,190 | 301,185 | Form 4 |
| 2026-04-01 | Adsett RogerChief Operating Officer | Saleplan | 6,715 | 163.18 | $1.10M | 188,155 | Form 4 |
| 2026-04-01 | Adsett RogerChief Operating Officer | Saleplan | 19,001 | 164.11 | $3.12M | 169,154 | Form 4 |
| 2026-04-01 | Adsett RogerChief Operating Officer | Saleplan | 62,344 | 164.95 | $10.28M | 106,810 | Form 4 |
| 2026-03-30 | Smith Michael AlexanderChief Legal Officer | Saleplan | 19,638 | 150.98 | $2.96M | 51,871 | Form 4 |
| 2026-03-19 | Lewis WilliamDirector, Chair and CEO | Saleplan | 1,629 | 142.17 | $231,595 | 310,255 | Form 4 |
| 2026-03-19 | Lewis WilliamDirector, Chair and CEO | Saleplan | 4,537 | 143.42 | $650,697 | 305,718 | Form 4 |
| 2026-03-19 | Lewis WilliamDirector, Chair and CEO | Saleplan | 4,533 | 144.11 | $653,251 | 301,185 | Form 4 |
| 2026-03-05 | Lewis WilliamDirector, Chair and CEO | Saleplan | 2,083 | 144.23 | $300,431 | 309,801 | Form 4 |
| 2026-03-05 | Lewis WilliamDirector, Chair and CEO | Saleplan | 2,589 | 145.27 | $376,104 | 307,212 | Form 4 |
| 2026-03-05 | Lewis WilliamDirector, Chair and CEO | Saleplan | 3,899 | 146.66 | $571,827 | 303,313 | Form 4 |
| 2026-03-05 | Lewis WilliamDirector, Chair and CEO | Saleplan | 2,128 | 147.54 | $313,965 | 301,185 | Form 4 |
| 2026-02-24 | Smith Michael AlexanderChief Legal Officer | Saleplan | 4,852 | 153.93 | $746,868 | 71,793 | Form 4 |
| 2026-02-24 | Smith Michael AlexanderChief Legal Officer | Saleplan | 4,151 | 155.06 | $643,654 | 67,642 | Form 4 |
| 2026-02-24 | Smith Michael AlexanderChief Legal Officer | Saleplan | 15,771 | 156.53 | $2.47M | 51,871 | Form 4 |
| 2026-02-19 | Lewis WilliamDirector, Chair and CEO | Saleplan | 1,988 | 149.17 | $296,550 | 309,896 | Form 4 |
| 2026-02-19 | Lewis WilliamDirector, Chair and CEO | Saleplan | 1,891 | 150.10 | $283,839 | 308,005 | Form 4 |
| 2026-02-19 | Lewis WilliamDirector, Chair and CEO | Saleplan | 3,413 | 151.12 | $515,773 | 304,592 | Form 4 |
| 2026-02-19 | Lewis WilliamDirector, Chair and CEO | Saleplan | 2,377 | 151.92 | $361,114 | 302,215 | Form 4 |
| 2026-02-19 | Lewis WilliamDirector, Chair and CEO | Saleplan | 1,030 | 153.38 | $157,981 | 301,185 | Form 4 |
| 2026-02-09 | Lewis WilliamDirector, Chair and CEO | Saleplan | 4,888 | 147.17 | $719,367 | 309,693 | Form 4 |
| 2026-02-09 | Lewis WilliamDirector, Chair and CEO | Saleplan | 7,221 | 148.02 | $1.07M | 302,472 | Form 4 |
| 2026-02-09 | Lewis WilliamDirector, Chair and CEO | Saleplan | 1,287 | 148.83 | $191,544 | 301,185 | Form 4 |
| 2026-02-05 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 869 | 152.44 | $132,470 | 83,243 | Form 4 |
| 2026-02-03 | Lewis WilliamDirector, Chair and CEO | Sale | 3,009 | 156.34 | $470,427 | 303,882 | Form 4 |
| 2026-02-03 | Bonstein SaraChief Financial Officer | Sale | 748 | 156.34 | $116,942 | 79,758 | Form 4 |
| 2026-02-03 | Adsett RogerChief Operating Officer | Sale | 791 | 156.17 | $123,530 | 106,810 | Form 4 |
| 2026-02-03 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 795 | 155.77 | $123,837 | 84,112 | Form 4 |
| 2026-02-03 | Smith Michael AlexanderChief Legal Officer | Sale | 640 | 156.27 | $100,013 | 56,397 | Form 4 |
| 2026-02-02 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 563 | 152.06 | $85,610 | 92,326 | Form 4 |
| 2026-02-02 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 928 | 153.16 | $142,132 | 91,398 | Form 4 |
| 2026-02-02 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 3,349 | 154.56 | $517,621 | 88,049 | Form 4 |
| 2026-02-02 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 3,042 | 155.46 | $472,909 | 85,007 | Form 4 |
| 2026-02-02 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 100 | 156.86 | $15,686 | 84,907 | Form 4 |
| 2026-01-20 | Lewis WilliamDirector, Chair and CEO | Saleplan | 1,006 | 156.80 | $157,741 | 316,584 | Form 4 |
| 2026-01-20 | Lewis WilliamDirector, Chair and CEO | Saleplan | 1,243 | 158.37 | $196,854 | 315,341 | Form 4 |
| 2026-01-20 | Lewis WilliamDirector, Chair and CEO | Saleplan | 5,967 | 158.99 | $948,693 | 309,374 | Form 4 |
| 2026-01-20 | Lewis WilliamDirector, Chair and CEO | Saleplan | 2,229 | 159.85 | $356,306 | 307,145 | Form 4 |
| 2026-01-20 | Lewis WilliamDirector, Chair and CEO | Saleplan | 254 | 160.70 | $40,818 | 306,891 | Form 4 |
| 2026-01-12 | Lewis WilliamDirector, Chair and CEO | Saleplan | 3,974 | 167.73 | $666,559 | 322,132 | Form 4 |
| 2026-01-12 | Lewis WilliamDirector, Chair and CEO | Saleplan | 7,176 | 168.63 | $1.21M | 314,956 | Form 4 |
| 2026-01-12 | Lewis WilliamDirector, Chair and CEO | Saleplan | 6,996 | 169.57 | $1.19M | 307,960 | Form 4 |
| 2026-01-12 | Lewis WilliamDirector, Chair and CEO | Saleplan | 160 | 170.24 | $27,238 | 307,800 | Form 4 |
| 2026-01-12 | Lewis WilliamDirector, Chair and CEO | Saleplan | 297 | 171.31 | $50,879 | 307,503 | Form 4 |
| 2026-01-12 | Lewis WilliamDirector, Chair and CEO | Saleplan | 297 | 172.36 | $51,191 | 307,206 | Form 4 |
| 2026-01-12 | Lewis WilliamDirector, Chair and CEO | Saleplan | 315 | 174.86 | $55,081 | 306,891 | Form 4 |
| 2026-01-09 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 1,887 | 186.19 | $351,341 | 84,907 | Form 4 |
| 2026-01-08 | Lewis WilliamDirector, Chair and CEO | Sale | 3,223 | 174.17 | $561,350 | 315,407 | Form 4 |
| 2026-01-08 | Bonstein SaraChief Financial Officer | Sale | 1,447 | 174.17 | $252,024 | 80,506 | Form 4 |
| 2026-01-08 | Adsett RogerChief Operating Officer | Sale | 2,059 | 174.17 | $358,616 | 107,601 | Form 4 |
| 2026-01-08 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 1,660 | 173.87 | $288,624 | 90,045 | Form 4 |
| 2026-01-08 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 3,251 | 174.17 | $566,227 | 86,794 | Form 4 |
| 2026-01-08 | Smith Michael AlexanderChief Legal Officer | Sale | 1,053 | 174.17 | $183,401 | 57,037 | Form 4 |
| 2026-01-07 | Lewis WilliamDirector, Chair and CEO | Sale | 2,357 | 175.07 | $412,640 | 318,630 | Form 4 |
| 2026-01-07 | Bonstein SaraChief Financial Officer | Sale | 1,678 | 175.07 | $293,767 | 81,953 | Form 4 |
| 2026-01-07 | Adsett RogerChief Operating Officer | Sale | 802 | 175.07 | $140,406 | 109,660 | Form 4 |
| 2026-01-07 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 1,434 | 175.84 | $252,155 | 91,705 | Form 4 |
| 2026-01-07 | Smith Michael AlexanderChief Legal Officer | Sale | 709 | 175.07 | $124,125 | 58,090 | Form 4 |
| 2026-01-06 | Lewis WilliamDirector, Chair and CEO | Sale | 4,096 | 173.33 | $709,960 | 320,987 | Form 4 |
| 2026-01-06 | Bonstein SaraChief Financial Officer | Sale | 1,517 | 173.33 | $262,942 | 83,631 | Form 4 |
| 2026-01-06 | Adsett RogerChief Operating Officer | Sale | 1,429 | 173.33 | $247,689 | 110,462 | Form 4 |
| 2026-01-06 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 4,783 | 173.47 | $829,707 | 98,541 | Form 4 |
| 2026-01-06 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 2,830 | 174.21 | $493,014 | 95,711 | Form 4 |
| 2026-01-06 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 957 | 175.01 | $167,485 | 94,754 | Form 4 |
| 2026-01-06 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 1,615 | 173.33 | $279,928 | 93,139 | Form 4 |
| 2026-01-06 | Smith Michael AlexanderChief Legal Officer | Sale | 1,396 | 173.33 | $241,969 | 58,799 | Form 4 |
| 2026-01-05 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 2,799 | 169.29 | $473,843 | 104,258 | Form 4 |
| 2026-01-05 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 3,205 | 170.61 | $546,805 | 101,053 | Form 4 |
| 2026-01-05 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 2,836 | 171.19 | $485,495 | 98,217 | Form 4 |
| 2026-01-05 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 286 | 171.92 | $49,169 | 97,931 | Form 4 |
| 2026-01-05 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 1,820 | 173.45 | $315,679 | 96,111 | Form 4 |
| 2026-01-05 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 655 | 174.28 | $114,153 | 95,456 | Form 4 |
| 2026-01-05 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 702 | 175.73 | $123,362 | 94,754 | Form 4 |
| 2026-01-02 | Schaeffer Orlov S NicoleChief People Strategy Officer | Saleplan | 31,030 | 174.28 | $5.41M | 98,014 | Form 4 |
| 2026-01-02 | Schaeffer Orlov S NicoleChief People Strategy Officer | Saleplan | 34,103 | 175.17 | $5.97M | 63,911 | Form 4 |
| 2026-01-02 | Schaeffer Orlov S NicoleChief People Strategy Officer | Saleplan | 12,832 | 176.08 | $2.26M | 51,079 | Form 4 |
| 2026-01-02 | Schaeffer Orlov S NicoleChief People Strategy Officer | Saleplan | 9,125 | 177.17 | $1.62M | 41,954 | Form 4 |
| 2026-01-02 | Schaeffer Orlov S NicoleChief People Strategy Officer | Saleplan | 200 | 177.78 | $35,556 | 41,754 | Form 4 |
| 2025-12-18 | Lewis WilliamDirector, Chair and CEO | Saleplan | 350 | 162.26 | $56,791 | 314,260 | Form 4 |
| 2025-12-18 | Lewis WilliamDirector, Chair and CEO | Saleplan | 1,465 | 163.19 | $239,073 | 312,795 | Form 4 |
| 2025-12-18 | Lewis WilliamDirector, Chair and CEO | Saleplan | 447 | 164.24 | $73,415 | 312,348 | Form 4 |
| 2025-12-18 | Lewis WilliamDirector, Chair and CEO | Saleplan | 697 | 165.21 | $115,151 | 311,651 | Form 4 |
| 2025-12-18 | Lewis WilliamDirector, Chair and CEO | Saleplan | 1,783 | 166.60 | $297,048 | 309,868 | Form 4 |
| 2025-12-18 | Lewis WilliamDirector, Chair and CEO | Saleplan | 1,431 | 167.29 | $239,392 | 308,437 | Form 4 |
| 2025-12-18 | Lewis WilliamDirector, Chair and CEO | Saleplan | 2,175 | 168.54 | $366,574 | 306,262 | Form 4 |
| 2025-12-18 | Lewis WilliamDirector, Chair and CEO | Saleplan | 1,938 | 169.58 | $328,646 | 304,324 | Form 4 |
| 2025-12-18 | Lewis WilliamDirector, Chair and CEO | Saleplan | 362 | 170.26 | $61,634 | 303,962 | Form 4 |
| 2025-12-18 | Lewis WilliamDirector, Chair and CEO | Saleplan | 51 | 171.20 | $8,731 | 303,911 | Form 4 |
| 2025-12-05 | Sharoky Melvin MDDirector | Sale | 20,000 | 205.01 | $4.10M | 243,948 | Form 4 |
| 2025-12-04 | Lewis WilliamDirector, Chair and CEO | Saleplan | 4,516 | 204.62 | $924,064 | 310,094 | Form 4 |
| 2025-12-04 | Lewis WilliamDirector, Chair and CEO | Saleplan | 2,222 | 205.66 | $456,977 | 307,872 | Form 4 |
| 2025-12-04 | Lewis WilliamDirector, Chair and CEO | Saleplan | 2,921 | 206.49 | $603,157 | 304,951 | Form 4 |
| 2025-12-04 | Lewis WilliamDirector, Chair and CEO | Saleplan | 1,040 | 207.42 | $215,717 | 303,911 | Form 4 |
| 2025-12-01 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 1,450 | 205.98 | $298,671 | 90,556 | Form 4 |
| 2025-12-01 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 5,886 | 207.03 | $1.22M | 84,670 | Form 4 |
| 2025-12-01 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 1,559 | 207.73 | $323,851 | 83,111 | Form 4 |
| 2025-11-24 | Anderson Elizabeth MDirector | Sale | 5,000 | 204.58 | $1.02M | 58,729 | Form 4 |
| 2025-11-17 | Lee LeoDirector | Sale | 3,212 | 193.51 | $621,554 | 126,465 | Form 4 |
| 2025-11-17 | Lee LeoDirector | Sale | 17,594 | 194.49 | $3.42M | 108,871 | Form 4 |
| 2025-11-17 | Lee LeoDirector | Sale | 14,944 | 195.39 | $2.92M | 93,927 | Form 4 |
| 2025-11-17 | Lee LeoDirector | Sale | 24,076 | 196.61 | $4.73M | 69,851 | Form 4 |
| 2025-11-17 | Lee LeoDirector | Sale | 15,174 | 197.40 | $3.00M | 54,677 | Form 4 |
| 2025-11-14 | Anderson Elizabeth MDirector | Sale | 10,000 | 195.87 | $1.96M | 63,729 | Form 4 |
| 2025-11-12 | Schaeffer Orlov S NicoleChief People Strategy Officer | Sale | 4,078 | 192.45 | $784,811 | 62,383 | Form 4 |
| 2025-11-12 | Schaeffer Orlov S NicoleChief People Strategy Officer | Sale | 6,575 | 193.64 | $1.27M | 55,808 | Form 4 |
| 2025-11-12 | Schaeffer Orlov S NicoleChief People Strategy Officer | Sale | 19,183 | 194.44 | $3.73M | 36,625 | Form 4 |
| 2025-11-12 | Schaeffer Orlov S NicoleChief People Strategy Officer | Sale | 164 | 195.88 | $32,124 | 36,461 | Form 4 |
| 2025-11-11 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 5,467 | 188.38 | $1.03M | 108,870 | Form 4 |
| 2025-11-11 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 12,224 | 189.36 | $2.31M | 96,646 | Form 4 |
| 2025-11-11 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 10,622 | 190.33 | $2.02M | 86,024 | Form 4 |
| 2025-11-11 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 2,913 | 191.04 | $556,500 | 83,111 | Form 4 |
| 2025-11-03 | Smith Michael AlexanderChief Legal Officer | Saleplan | 1,342 | 181.01 | $242,915 | 80,690 | Form 4 |
| 2025-11-03 | Smith Michael AlexanderChief Legal Officer | Saleplan | 7,619 | 181.88 | $1.39M | 73,071 | Form 4 |
| 2025-11-03 | Smith Michael AlexanderChief Legal Officer | Saleplan | 4,286 | 182.60 | $782,624 | 68,785 | Form 4 |
| 2025-11-03 | Smith Michael AlexanderChief Legal Officer | Saleplan | 4,032 | 183.92 | $741,565 | 64,753 | Form 4 |
| 2025-11-03 | Smith Michael AlexanderChief Legal Officer | Saleplan | 3,243 | 184.91 | $599,663 | 61,510 | Form 4 |
| 2025-11-03 | Smith Michael AlexanderChief Legal Officer | Saleplan | 3,636 | 185.93 | $676,041 | 57,874 | Form 4 |
| 2025-11-03 | Smith Michael AlexanderChief Legal Officer | Saleplan | 1,572 | 187.15 | $294,200 | 56,302 | Form 4 |
| 2025-11-03 | Smith Michael AlexanderChief Legal Officer | Saleplan | 1,400 | 187.97 | $263,158 | 54,902 | Form 4 |
| 2025-09-12 | Sharoky Melvin MDDirector | Sale | 10,000 | 145.39 | $1.45M | 262,675 | Form 4 |
| 2025-09-12 | Schaeffer Orlov S NicoleChief People Strategy Officer | Saleplan | 32,091 | 144.60 | $4.64M | 80,890 | Form 4 |
| 2025-09-12 | Schaeffer Orlov S NicoleChief People Strategy Officer | Saleplan | 30,967 | 145.67 | $4.51M | 49,923 | Form 4 |
| 2025-09-12 | Schaeffer Orlov S NicoleChief People Strategy Officer | Saleplan | 7,304 | 146.57 | $1.07M | 42,619 | Form 4 |
| 2025-09-12 | Schaeffer Orlov S NicoleChief People Strategy Officer | Saleplan | 6,158 | 147.46 | $908,059 | 36,461 | Form 4 |
| 2025-09-02 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 19,066 | 141.27 | $2.69M | 250,693 | Form 4 |
| 2025-09-02 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 5,877 | 142.03 | $834,710 | 244,816 | Form 4 |
| 2025-09-02 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 35,245 | 143.16 | $5.05M | 209,571 | Form 4 |
| 2025-09-02 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 28,063 | 144.05 | $4.04M | 181,508 | Form 4 |
| 2025-09-02 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 63,782 | 145.33 | $9.27M | 117,726 | Form 4 |
| 2025-09-02 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 34,615 | 146.05 | $5.06M | 83,111 | Form 4 |
| 2025-09-02 | Smith Michael AlexanderChief Legal Officer | Saleplan | 1,354 | 141.16 | $191,131 | 77,820 | Form 4 |
| 2025-09-02 | Smith Michael AlexanderChief Legal Officer | Saleplan | 1,100 | 142.06 | $156,266 | 76,720 | Form 4 |
| 2025-09-02 | Smith Michael AlexanderChief Legal Officer | Saleplan | 7,391 | 143.16 | $1.06M | 69,329 | Form 4 |
| 2025-09-02 | Smith Michael AlexanderChief Legal Officer | Saleplan | 8,300 | 144.16 | $1.20M | 61,029 | Form 4 |
| 2025-09-02 | Smith Michael AlexanderChief Legal Officer | Saleplan | 4,944 | 145.18 | $717,770 | 56,085 | Form 4 |
| 2025-09-02 | Smith Michael AlexanderChief Legal Officer | Saleplan | 1,183 | 145.89 | $172,588 | 54,902 | Form 4 |
| 2025-08-20 | Sharoky Melvin MDDirector | Sale | 10,000 | 129.50 | $1.29M | 274,516 | Form 4 |
| 2025-08-19 | Adsett RogerChief Operating Officer | Sale | 20,193 | 127.42 | $2.57M | 110,444 | Form 4 |
| 2025-08-19 | Adsett RogerChief Operating Officer | Sale | 4,807 | 128.27 | $616,594 | 105,637 | Form 4 |
| 2025-08-18 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 2,968 | 127.59 | $378,687 | 237,821 | Form 4 |
| 2025-08-18 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 2,481 | 128.76 | $319,454 | 235,340 | Form 4 |
| 2025-08-18 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 1,416 | 129.47 | $183,330 | 233,924 | Form 4 |
| 2025-08-14 | Schaeffer Orlov S NicoleChief People Strategy Officer | Sale | 3,554 | 126.57 | $449,830 | 86,210 | Form 4 |
| 2025-08-14 | Schaeffer Orlov S NicoleChief People Strategy Officer | Sale | 5,746 | 127.71 | $733,822 | 80,464 | Form 4 |
| 2025-08-14 | Schaeffer Orlov S NicoleChief People Strategy Officer | Sale | 700 | 128.16 | $89,712 | 79,764 | Form 4 |
| 2025-08-12 | Sharoky Melvin MDDirector | Sale | 10,000 | 121.58 | $1.22M | 290,616 | Form 4 |
| 2025-08-04 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 1,693 | 108.80 | $184,198 | 239,061 | Form 4 |
| 2025-08-04 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 3,199 | 109.68 | $350,866 | 235,862 | Form 4 |
| 2025-08-04 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 1,938 | 110.91 | $214,944 | 233,924 | Form 4 |
| 2025-08-04 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 8,715 | 109.50 | $954,292 | 83,111 | Form 4 |
| 2025-07-21 | Bonstein SaraChief Financial Officer | Saleplan | 32,090 | 102.38 | $3.29M | 99,815 | Form 4 |
| 2025-07-21 | Bonstein SaraChief Financial Officer | Saleplan | 26,310 | 103.03 | $2.71M | 73,505 | Form 4 |
| 2025-07-15 | Smith Michael AlexanderChief Legal Officer | Saleplan | 933 | 102.51 | $95,642 | 66,394 | Form 4 |
| 2025-07-15 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 2,168 | 101.71 | $220,507 | 238,586 | Form 4 |
| 2025-07-15 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 4,492 | 102.66 | $461,149 | 234,094 | Form 4 |
| 2025-07-15 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 170 | 103.32 | $17,564 | 233,924 | Form 4 |
| 2025-07-11 | Smith Michael AlexanderChief Legal Officer | Saleplan | 748 | 96.41 | $72,115 | 67,327 | Form 4 |
| 2025-07-07 | Bonstein SaraChief Financial Officer | Saleplan | 35,583 | 95.66 | $3.40M | 106,198 | Form 4 |
| 2025-07-07 | Bonstein SaraChief Financial Officer | Saleplan | 22,181 | 96.19 | $2.13M | 84,017 | Form 4 |
| 2025-07-01 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 3,666 | 97.73 | $358,278 | 237,088 | Form 4 |
| 2025-07-01 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 2,349 | 98.83 | $232,152 | 234,739 | Form 4 |
| 2025-07-01 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 815 | 99.61 | $81,182 | 233,924 | Form 4 |
| 2025-06-23 | Bonstein SaraChief Financial Officer | Saleplan | 49,104 | 101.71 | $4.99M | 102,197 | Form 4 |
| 2025-06-23 | Bonstein SaraChief Financial Officer | Saleplan | 8,661 | 102.15 | $884,721 | 93,536 | Form 4 |
| 2025-06-16 | Adsett RogerChief Operating Officer | Saleplan | 6,500 | 98.50 | $640,250 | 134,823 | Form 4 |
| 2025-06-16 | Adsett RogerChief Operating Officer | Saleplan | 4,186 | 99.32 | $415,754 | 130,637 | Form 4 |
| 2025-06-16 | Lewis WilliamDirector, Chair and CEO | Saleplan | 442 | 98.51 | $43,541 | 308,316 | Form 4 |
| 2025-06-16 | Lewis WilliamDirector, Chair and CEO | Saleplan | 1,558 | 99.65 | $155,255 | 306,758 | Form 4 |
| 2025-06-16 | Lewis WilliamDirector, Chair and CEO | Saleplan | 2,300 | 100.70 | $231,610 | 304,458 | Form 4 |
| 2025-06-16 | Lewis WilliamDirector, Chair and CEO | Saleplan | 904 | 101.39 | $91,657 | 303,554 | Form 4 |
| 2025-06-16 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 7,000 | 98.50 | $689,500 | 356,729 | Form 4 |
| 2025-06-16 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 32,490 | 99.51 | $3.23M | 324,239 | Form 4 |
| 2025-06-16 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 48,531 | 100.54 | $4.88M | 275,708 | Form 4 |
| 2025-06-16 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 41,784 | 101.23 | $4.23M | 233,924 | Form 4 |
| 2025-06-11 | Schaeffer Orlov S NicoleChief People Strategy Officer | Saleplan | 35,072 | 91.68 | $3.22M | 153,507 | Form 4 |
| 2025-06-11 | Schaeffer Orlov S NicoleChief People Strategy Officer | Saleplan | 18,319 | 92.73 | $1.70M | 135,188 | Form 4 |
| 2025-06-11 | Schaeffer Orlov S NicoleChief People Strategy Officer | Saleplan | 10,781 | 93.48 | $1.01M | 124,407 | Form 4 |
| 2025-06-11 | Schaeffer Orlov S NicoleChief People Strategy Officer | Saleplan | 34,500 | 95.49 | $3.29M | 89,907 | Form 4 |
| 2025-06-11 | Schaeffer Orlov S NicoleChief People Strategy Officer | Saleplan | 500 | 96.02 | $48,010 | 89,407 | Form 4 |
| 2025-06-11 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 19,423 | 94.50 | $1.84M | 83,111 | Form 4 |
| 2025-06-10 | Bonstein SaraChief Financial Officer | Saleplan | 7,277 | 87.12 | $633,972 | 153,901 | Form 4 |
| 2025-06-10 | Bonstein SaraChief Financial Officer | Saleplan | 7,310 | 88.29 | $645,400 | 146,591 | Form 4 |
| 2025-06-10 | Bonstein SaraChief Financial Officer | Saleplan | 20,926 | 88.99 | $1.86M | 125,665 | Form 4 |
| 2025-06-10 | Bonstein SaraChief Financial Officer | Saleplan | 15,825 | 89.85 | $1.42M | 109,840 | Form 4 |
| 2025-06-10 | Bonstein SaraChief Financial Officer | Saleplan | 6,328 | 90.93 | $575,405 | 103,512 | Form 4 |
| 2025-06-10 | Bonstein SaraChief Financial Officer | Saleplan | 100 | 91.66 | $9,166 | 103,412 | Form 4 |
| 2025-06-10 | Schaeffer Orlov S NicoleChief People Strategy Officer | Saleplan | 38,300 | 88.64 | $3.39M | 118,579 | Form 4 |
| 2025-06-10 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 25,740 | 88.64 | $2.28M | 83,111 | Form 4 |
| 2025-06-05 | Smith Michael AlexanderChief Legal Officer | Saleplan | 1,879 | 73.50 | $138,106 | 67,718 | Form 4 |
| 2025-06-04 | McGirr David W JDirector | Saleplan | 3,000 | 73.27 | $219,810 | 97,723 | Form 4 |
| 2025-06-03 | Lewis WilliamDirector, Chair and CEO | Saleplan | 5,472 | 71.50 | $391,248 | 308,758 | Form 4 |
| 2025-06-03 | McGirr David W JDirector | Saleplan | 3,250 | 71.30 | $231,725 | 100,723 | Form 4 |
| 2025-06-03 | Schaeffer Orlov S NicoleChief People Strategy Officer | Sale | 1,642 | 71.50 | $117,403 | 118,579 | Form 4 |
| 2025-06-03 | Bonstein SaraChief Financial Officer | Sale | 1,579 | 71.50 | $112,898 | 113,288 | Form 4 |
| 2025-06-03 | Adsett RogerChief Operating Officer | Sale | 1,860 | 71.50 | $132,990 | 141,323 | Form 4 |
| 2025-06-03 | Flammer Martina M.d.Chief Medical Officer | Sale | 1,686 | 71.50 | $120,549 | 83,111 | Form 4 |
| 2025-06-03 | Smith Michael AlexanderChief Legal Officer | Sale | 1,448 | 71.50 | $103,532 | 69,597 | Form 4 |
| 2025-06-02 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 1,000 | 70.23 | $70,230 | 239,754 | Form 4 |
| 2025-06-02 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 4,400 | 71.35 | $313,940 | 235,354 | Form 4 |
| 2025-06-02 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 1,430 | 71.94 | $102,874 | 233,924 | Form 4 |
| 2025-05-30 | Smith Michael AlexanderChief Legal Officer | Saleplan | 6,327 | 68.56 | $433,779 | 91,045 | Form 4 |
| 2025-05-30 | Smith Michael AlexanderChief Legal Officer | Saleplan | 20,000 | 70.00 | $1.40M | 71,045 | Form 4 |
| 2025-05-21 | Desjardins ClarissaDirector | Buyindirect | 1,130 | 66.35 | $74,976 | 3,025 | Form 4 |
| 2025-05-20 | Lewis WilliamDirector, Chair and CEO | Saleplan | 9,489 | 66.87 | $634,529 | 325,798 | Form 4 |
| 2025-05-20 | Lewis WilliamDirector, Chair and CEO | Saleplan | 4,480 | 67.96 | $304,461 | 321,318 | Form 4 |
| 2025-05-20 | Lewis WilliamDirector, Chair and CEO | Saleplan | 7,088 | 68.49 | $485,457 | 314,230 | Form 4 |
| 2025-05-20 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 2,863 | 66.90 | $191,535 | 237,891 | Form 4 |
| 2025-05-20 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 2,251 | 68.13 | $153,361 | 235,640 | Form 4 |
| 2025-05-20 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 1,716 | 68.54 | $117,615 | 233,924 | Form 4 |
| 2025-05-20 | Desjardins ClarissaDirector | Buyindirect | 1,895 | 66.87 | $126,719 | 1,895 | Form 4 |
| 2025-05-16 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 1,799 | 67.53 | $121,486 | 84,797 | Form 4 |
| 2025-05-15 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 9,925 | 65.47 | $649,790 | 86,596 | Form 4 |
| 2025-05-14 | Adsett RogerChief Operating Officer | Sale | 1,925 | 65.61 | $126,299 | 136,675 | Form 4 |
| 2025-05-14 | Bonstein SaraChief Financial Officer | Sale | 1,634 | 65.61 | $107,207 | 108,359 | Form 4 |
| 2025-05-14 | Flammer Martina M.d.Chief Medical Officer | Sale | 1,744 | 65.61 | $114,424 | 90,013 | Form 4 |
| 2025-05-14 | Lewis WilliamDirector, Chair and CEO | Sale | 3,771 | 65.61 | $247,415 | 312,973 | Form 4 |
| 2025-05-14 | Schaeffer Orlov S NicoleChief People Strategy Officer | Sale | 1,236 | 65.61 | $81,094 | 114,643 | Form 4 |
| 2025-05-14 | Smith Michael AlexanderChief Legal Officer | Sale | 409 | 65.61 | $26,834 | 91,794 | Form 4 |
| 2025-05-13 | Adsett RogerChief Operating Officer | Sale | 7,482 | 67.81 | $507,354 | 138,600 | Form 4 |
| 2025-05-13 | Bonstein SaraChief Financial Officer | Sale | 8,870 | 67.81 | $601,475 | 109,993 | Form 4 |
| 2025-05-13 | Flammer Martina M.d.Chief Medical Officer | Sale | 8,408 | 67.81 | $570,146 | 91,757 | Form 4 |
| 2025-05-13 | Lewis WilliamDirector, Chair and CEO | Sale | 9,743 | 66.40 | $646,935 | 324,443 | Form 4 |
| 2025-05-13 | Lewis WilliamDirector, Chair and CEO | Sale | 7,699 | 67.70 | $521,222 | 316,744 | Form 4 |
| 2025-05-13 | Schaeffer Orlov S NicoleChief People Strategy Officer | Sale | 4,999 | 67.81 | $338,982 | 115,879 | Form 4 |
| 2025-05-13 | Smith Michael AlexanderChief Legal Officer | Sale | 4,407 | 67.81 | $298,839 | 92,203 | Form 4 |
| 2025-05-01 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 2,629 | 72.24 | $189,919 | 238,125 | Form 4 |
| 2025-05-01 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 4,201 | 72.78 | $305,749 | 233,924 | Form 4 |
| 2025-04-15 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 3,334 | 69.62 | $232,113 | 237,420 | Form 4 |
| 2025-04-15 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 2,896 | 70.54 | $204,284 | 234,524 | Form 4 |
| 2025-04-15 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 600 | 71.30 | $42,780 | 233,924 | Form 4 |
| 2025-04-01 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 3,021 | 72.29 | $218,388 | 237,733 | Form 4 |
| 2025-04-01 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 772 | 73.44 | $56,696 | 236,961 | Form 4 |
| 2025-04-01 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 2,232 | 74.78 | $166,909 | 234,729 | Form 4 |
| 2025-04-01 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 805 | 75.26 | $60,584 | 233,924 | Form 4 |
| 2025-03-17 | Lewis WilliamDirector, Chair and CEO | Saleplan | 4,727 | 75.91 | $358,827 | 348,209 | Form 4 |
| 2025-03-17 | Lewis WilliamDirector, Chair and CEO | Saleplan | 5,907 | 76.87 | $454,071 | 342,302 | Form 4 |
| 2025-03-17 | Lewis WilliamDirector, Chair and CEO | Saleplan | 8,116 | 77.79 | $631,344 | 334,186 | Form 4 |
| 2025-03-17 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 2,023 | 76.00 | $153,748 | 238,731 | Form 4 |
| 2025-03-17 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 2,070 | 77.01 | $159,411 | 236,661 | Form 4 |
| 2025-03-17 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 2,737 | 77.83 | $213,021 | 233,924 | Form 4 |
| 2025-03-03 | Lewis WilliamDirector, Chair and CEO | Saleplan | 7,317 | 76.24 | $557,848 | 345,619 | Form 4 |
| 2025-03-03 | Lewis WilliamDirector, Chair and CEO | Saleplan | 758 | 77.75 | $58,934 | 344,861 | Form 4 |
| 2025-03-03 | Lewis WilliamDirector, Chair and CEO | Saleplan | 7,763 | 78.61 | $610,249 | 337,098 | Form 4 |
| 2025-03-03 | Lewis WilliamDirector, Chair and CEO | Saleplan | 2,785 | 79.43 | $221,213 | 334,313 | Form 4 |
| 2025-03-03 | Lewis WilliamDirector, Chair and CEO | Saleplan | 127 | 80.90 | $10,274 | 334,186 | Form 4 |
| 2025-03-03 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 2,671 | 76.23 | $203,610 | 238,083 | Form 4 |
| 2025-03-03 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 1,486 | 78.20 | $116,205 | 236,597 | Form 4 |
| 2025-03-03 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 2,250 | 78.97 | $177,682 | 234,347 | Form 4 |
| 2025-03-03 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 377 | 79.73 | $30,058 | 233,970 | Form 4 |
| 2025-03-03 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 46 | 80.90 | $3,721 | 233,924 | Form 4 |
| 2025-02-18 | Bonstein SaraChief Financial Officer | Saleplan | 17,622 | 80.28 | $1.41M | 119,563 | Form 4 |
| 2025-02-18 | Bonstein SaraChief Financial Officer | Saleplan | 700 | 81.00 | $56,700 | 118,863 | Form 4 |
| 2025-02-18 | Lewis WilliamDirector, Chair and CEO | Saleplan | 1,253 | 79.95 | $100,177 | 351,683 | Form 4 |
| 2025-02-18 | Lewis WilliamDirector, Chair and CEO | Saleplan | 16,743 | 81.08 | $1.36M | 334,940 | Form 4 |
| 2025-02-18 | Lewis WilliamDirector, Chair and CEO | Saleplan | 754 | 81.67 | $61,579 | 334,186 | Form 4 |
| 2025-02-18 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 456 | 80.00 | $36,480 | 240,298 | Form 4 |
| 2025-02-18 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 6,074 | 81.07 | $492,419 | 234,224 | Form 4 |
| 2025-02-18 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 300 | 81.81 | $24,543 | 233,924 | Form 4 |
| 2025-02-12 | Bonstein SaraChief Financial Officer | Saleplan | 5,019 | 80.00 | $401,520 | 137,185 | Form 4 |
| 2025-02-11 | Bonstein SaraChief Financial Officer | Saleplan | 13,302 | 80.00 | $1.06M | 142,204 | Form 4 |
| 2025-02-10 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 9,729 | 77.02 | $749,328 | 128,264 | Form 4 |
| 2025-02-10 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 5,089 | 78.36 | $398,774 | 123,175 | Form 4 |
| 2025-02-10 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 23,010 | 79.33 | $1.83M | 100,165 | Form 4 |
| 2025-02-10 | Adsett RogerChief Operating Officer | Saleplan | 11,053 | 77.02 | $851,302 | 178,004 | Form 4 |
| 2025-02-10 | Adsett RogerChief Operating Officer | Saleplan | 5,781 | 78.36 | $452,999 | 172,223 | Form 4 |
| 2025-02-10 | Adsett RogerChief Operating Officer | Saleplan | 26,141 | 79.33 | $2.07M | 146,082 | Form 4 |
| 2025-02-07 | Wise John DraytonChief Commercial Officer | Sale | 10 | 78.91 | $789 | 133,015 | Form 4 |
| 2025-02-07 | Adsett RogerChief Operating Officer | Sale | 100 | 79.57 | $7,957 | 189,057 | Form 4 |
| 2025-02-07 | Flammer Martina M.d.Chief Medical Officer | Sale | 60 | 79.59 | $4,775 | 137,993 | Form 4 |
| 2025-02-06 | Smith Michael AlexanderChief Legal Officer | Sale | 20,650 | 80.90 | $1.67M | 96,610 | Form 4 |
| 2025-02-06 | Bonstein SaraChief Financial Officer | Sale | 28,390 | 80.90 | $2.30M | 155,506 | Form 4 |
| 2025-02-06 | Wise John DraytonChief Commercial Officer | Sale | 7,910 | 80.90 | $639,919 | 133,025 | Form 4 |
| 2025-02-06 | Lewis WilliamDirector, Chair and CEO | Sale | 79,350 | 80.90 | $6.42M | 453,894 | Form 4 |
| 2025-02-06 | Adsett RogerChief Operating Officer | Sale | 45,605 | 80.90 | $3.69M | 189,157 | Form 4 |
| 2025-02-06 | Schaeffer Orlov S NicoleChief People Strategy Officer | Sale | 23,500 | 80.90 | $1.90M | 120,878 | Form 4 |
| 2025-02-06 | Flammer Martina M.d.Chief Medical Officer | Sale | 33,055 | 80.90 | $2.67M | 138,053 | Form 4 |
| 2025-02-03 | Lewis WilliamDirector, Chair and CEO | Saleplan | 241 | 75.25 | $18,135 | 398,043 | Form 4 |
| 2025-02-03 | Lewis WilliamDirector, Chair and CEO | Saleplan | 1,872 | 76.35 | $142,927 | 396,171 | Form 4 |
| 2025-02-03 | Lewis WilliamDirector, Chair and CEO | Saleplan | 9,869 | 77.97 | $769,486 | 386,302 | Form 4 |
| 2025-02-03 | Lewis WilliamDirector, Chair and CEO | Saleplan | 6,768 | 78.44 | $530,882 | 379,534 | Form 4 |
| 2025-02-03 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 41 | 74.86 | $3,069 | 240,713 | Form 4 |
| 2025-02-03 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 745 | 76.43 | $56,940 | 239,968 | Form 4 |
| 2025-02-03 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 3,463 | 77.95 | $269,941 | 236,505 | Form 4 |
| 2025-02-03 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 2,581 | 78.40 | $202,350 | 233,924 | Form 4 |
| 2025-01-30 | Schaeffer Orlov S NicoleChief People Strategy Officer | Saleplan | 91,140 | 80.00 | $7.29M | 97,083 | Form 4 |
| 2025-01-15 | Lewis WilliamDirector, Chair and CEO | Saleplan | 6,636 | 69.39 | $460,472 | 404,703 | Form 4 |
| 2025-01-15 | Lewis WilliamDirector, Chair and CEO | Saleplan | 22,696 | 70.32 | $1.60M | 382,007 | Form 4 |
| 2025-01-15 | Lewis WilliamDirector, Chair and CEO | Saleplan | 2,473 | 71.05 | $175,707 | 379,534 | Form 4 |
| 2025-01-15 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 1,499 | 69.40 | $104,031 | 239,255 | Form 4 |
| 2025-01-15 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 4,700 | 70.31 | $330,457 | 234,555 | Form 4 |
| 2025-01-15 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 631 | 71.01 | $44,807 | 233,924 | Form 4 |
| 2025-01-14 | Schaeffer Orlov S NicoleChief People Strategy Officer | Saleplan | 872 | 68.72 | $59,924 | 97,083 | Form 4 |
| 2025-01-14 | Adsett RogerChief Operating Officer | Saleplan | 1,457 | 68.72 | $100,125 | 146,082 | Form 4 |
| 2025-01-14 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 1,384 | 68.72 | $95,108 | 100,165 | Form 4 |
| 2025-01-10 | Adsett RogerChief Operating Officer | Saleplan | 1,298 | 63.86 | $82,890 | 151,143 | Form 4 |
| 2025-01-10 | Adsett RogerChief Operating Officer | Saleplan | 3,604 | 63.62 | $229,286 | 147,539 | Form 4 |
| 2025-01-10 | Smith Michael AlexanderChief Legal Officer | Sale | 319 | 63.38 | $20,218 | 69,965 | Form 4 |
| 2025-01-10 | Lewis WilliamDirector, Chair and CEO | Sale | 2,978 | 63.36 | $188,686 | 392,589 | Form 4 |
| 2025-01-10 | Wise John DraytonChief Commercial Officer | Saleplan | 287 | 65.40 | $18,770 | 125,562 | Form 4 |
| 2025-01-10 | Schaeffer Orlov S NicoleChief People Strategy Officer | Saleplan | 965 | 63.87 | $61,635 | 101,047 | Form 4 |
| 2025-01-10 | Schaeffer Orlov S NicoleChief People Strategy Officer | Saleplan | 3,092 | 63.62 | $196,713 | 97,955 | Form 4 |
| 2025-01-10 | Bonstein SaraChief Financial Officer | Sale | 1,066 | 63.72 | $67,926 | 118,863 | Form 4 |
| 2025-01-10 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 1,371 | 63.73 | $87,374 | 106,350 | Form 4 |
| 2025-01-10 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 4,801 | 63.62 | $305,440 | 101,549 | Form 4 |
| 2025-01-08 | Adsett RogerChief Operating Officer | Saleplan | 1,882 | 66.10 | $124,400 | 145,784 | Form 4 |
| 2025-01-08 | Smith Michael AlexanderChief Legal Officer | Sale | 1,064 | 66.21 | $70,447 | 64,578 | Form 4 |
| 2025-01-08 | Lewis WilliamDirector, Chair and CEO | Sale | 3,999 | 65.96 | $263,774 | 372,743 | Form 4 |
| 2025-01-08 | Wise John DraytonChief Commercial Officer | Saleplan | 392 | 66.21 | $25,954 | 119,192 | Form 4 |
| 2025-01-08 | Schaeffer Orlov S NicoleChief People Strategy Officer | Saleplan | 1,209 | 65.84 | $79,601 | 96,306 | Form 4 |
| 2025-01-08 | Bonstein SaraChief Financial Officer | Sale | 1,464 | 66.05 | $96,697 | 113,272 | Form 4 |
| 2025-01-08 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 1,702 | 66.16 | $112,604 | 101,064 | Form 4 |
| 2025-01-07 | Adsett RogerChief Operating Officer | Saleplan | 2,444 | 65.95 | $161,182 | 147,666 | Form 4 |
| 2025-01-07 | Smith Michael AlexanderChief Legal Officer | Sale | 2,306 | 65.98 | $152,150 | 65,642 | Form 4 |
| 2025-01-07 | Lewis WilliamDirector, Chair and CEO | Sale | 8,218 | 66.02 | $542,552 | 376,742 | Form 4 |
| 2025-01-07 | Wise John DraytonChief Commercial Officer | Saleplan | 10,000 | 65.98 | $659,800 | 122,492 | Form 4 |
| 2025-01-07 | Wise John DraytonChief Commercial Officer | Saleplan | 2,908 | 65.87 | $191,550 | 119,584 | Form 4 |
| 2025-01-07 | Schaeffer Orlov S NicoleChief People Strategy Officer | Saleplan | 2,596 | 65.88 | $171,024 | 97,515 | Form 4 |
| 2025-01-07 | Bonstein SaraChief Financial Officer | Sale | 3,470 | 65.70 | $227,979 | 114,736 | Form 4 |
| 2025-01-07 | Flammer Martina M.d.Chief Medical Officer | Saleplan | 3,344 | 65.91 | $220,403 | 102,766 | Form 4 |
| 2025-01-02 | Lewis WilliamDirector, Chair and CEO | Saleplan | 18,750 | 69.84 | $1.31M | 384,960 | Form 4 |
| 2025-01-02 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 6,830 | 69.86 | $477,144 | 233,924 | Form 4 |
| 2024-12-19 | Lewis WilliamDirector, Chair and CEO | Saleplan | 13,162 | 69.65 | $916,733 | 390,548 | Form 4 |
| 2024-12-19 | Lewis WilliamDirector, Chair and CEO | Saleplan | 5,588 | 70.52 | $394,066 | 384,960 | Form 4 |
| 2024-12-19 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 5,240 | 69.71 | $365,280 | 235,514 | Form 4 |
| 2024-12-19 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 1,590 | 70.61 | $112,270 | 233,924 | Form 4 |
| 2024-12-12 | Lewis WilliamDirector, Chair and CEO | Saleplan | 11,504 | 72.58 | $834,960 | 392,206 | Form 4 |
| 2024-12-12 | Lewis WilliamDirector, Chair and CEO | Saleplan | 6,847 | 73.56 | $503,665 | 385,359 | Form 4 |
| 2024-12-12 | Lewis WilliamDirector, Chair and CEO | Saleplan | 399 | 74.23 | $29,618 | 384,960 | Form 4 |
| 2024-12-12 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 4,087 | 72.57 | $296,594 | 236,667 | Form 4 |
| 2024-12-12 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 2,562 | 73.55 | $188,435 | 234,105 | Form 4 |
| 2024-12-12 | Lewis WilliamDirector, Chair and CEO | Saleplanindirect | 181 | 74.22 | $13,434 | 233,924 | Form 4 |
Grants, exercises and other transactions
Pay, tax and paperwork rather than a choice to trade at the market price. Two years.
108 × option exercise42 × grant or award30 × gift
Show them
| Date | Insider | What | Shares | Price | Holds after | Filing |
|---|---|---|---|---|---|---|
| 2026-08-10 | Adsett RogerChief Operating Officer | Option exercise M | +82,280 | 13.67 | 181,024 | Form 4 |
| 2026-08-10 | Adsett RogerChief Operating Officer | Option exercise M | +76,600 | 17.16 | 257,624 | Form 4 |
| 2026-08-10 | Adsett RogerChief Operating Officer | Option exercise M | +80,970 | 30.46 | 338,594 | Form 4 |
| 2026-08-06 | Flammer Martina M.d.Chief Medical Officer | Option exercise M | +18,278 | 18.95 | 78,764 | Form 4 |
| 2026-08-06 | Flammer Martina M.d.Chief Medical Officer | Option exercise M | +8,895 | 25.83 | 87,659 | Form 4 |
| 2026-07-23 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,260 | 30.46 | 265,318 | Form 4 |
| 2026-07-23 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +4,440 | 17.16 | 269,758 | Form 4 |
| 2026-07-09 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,259 | 30.46 | 265,317 | Form 4 |
| 2026-07-09 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +4,440 | 17.16 | 269,757 | Form 4 |
| 2026-07-06 | Flammer Martina M.d.Chief Medical Officer | Option exercise M | +7,945 | 29.13 | 68,431 | Form 4 |
| 2026-07-06 | Flammer Martina M.d.Chief Medical Officer | Option exercise M | +4,357 | 19.74 | 72,788 | Form 4 |
| 2026-06-25 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +12,518 | 30.46 | 271,435 | Form 4 |
| 2026-06-25 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +8,880 | 17.16 | 280,315 | Form 4 |
| 2026-06-23 | Butera SamueleSVP, GM, Global Respiratory | Grant or award A | +7,342 | – | 7,342 | Form 4 |
| 2026-05-18 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,259 | 30.46 | 294,161 | Form 4 |
| 2026-05-18 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +4,440 | 17.16 | 298,601 | Form 4 |
| 2026-05-13 | Sharoky Melvin MDDirector | Grant or award A | +3,305 | – | 246,081 | Form 4 |
| 2026-05-13 | Schafer CarolDirector | Grant or award A | +3,305 | – | 66,622 | Form 4 |
| 2026-05-13 | Brennan David RDirector | Grant or award A | +3,305 | – | 64,238 | Form 4 |
| 2026-05-13 | Lee LeoDirector | Grant or award A | +3,305 | – | 57,971 | Form 4 |
| 2026-05-13 | Anderson Elizabeth MDirector | Grant or award A | +3,305 | – | 62,034 | Form 4 |
| 2026-05-13 | Desjardins ClarissaDirector | Grant or award A | +3,305 | – | 70,312 | Form 4 |
| 2026-05-11 | Flammer Martina M.d.Chief Medical Officer | Option exercise M | +12,949 | 17.07 | 96,192 | Form 4 |
| 2026-05-04 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,259 | 30.46 | 307,444 | Form 4 |
| 2026-05-04 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +4,440 | 17.16 | 311,884 | Form 4 |
| 2026-04-16 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,259 | 30.46 | 307,444 | Form 4 |
| 2026-04-16 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +4,440 | 17.16 | 311,884 | Form 4 |
| 2026-04-06 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,259 | 30.46 | 307,444 | Form 4 |
| 2026-04-06 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +4,440 | 17.16 | 311,884 | Form 4 |
| 2026-04-01 | Adsett RogerChief Operating Officer | Option exercise M | +88,060 | 14.56 | 194,870 | Form 4 |
| 2026-03-30 | Smith Michael AlexanderChief Legal Officer | Option exercise M | +5,649 | 17.07 | 57,520 | Form 4 |
| 2026-03-30 | Smith Michael AlexanderChief Legal Officer | Option exercise M | +13,989 | 27.89 | 71,509 | Form 4 |
| 2026-03-19 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,259 | 30.46 | 307,444 | Form 4 |
| 2026-03-19 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +4,440 | 17.16 | 311,884 | Form 4 |
| 2026-03-05 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,259 | 30.46 | 307,444 | Form 4 |
| 2026-03-05 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +4,440 | 17.16 | 311,884 | Form 4 |
| 2026-03-03 | Sharoky Melvin MDDirector | Gift G | −100 | – | 242,776 | Form 4 |
| 2026-02-25 | Sharoky Melvin MDDirector | Gift G | −1,072 | – | 242,876 | Form 4 |
| 2026-02-25 | Sharoky Melvin MDDirector | Gift G | +243 | – | 5,423 | Form 4 |
| 2026-02-25 | Sharoky Melvin MDDirector | Gift G | +243 | – | 3,724 | Form 4 |
| 2026-02-25 | Sharoky Melvin MDDirector | Gift G | +243 | – | 5,007 | Form 4 |
| 2026-02-25 | Sharoky Melvin MDDirector | Gift G | +243 | – | 819 | Form 4 |
| 2026-02-24 | Smith Michael AlexanderChief Legal Officer | Option exercise M | +20,248 | 17.07 | 76,645 | Form 4 |
| 2026-02-23 | Brennan David RDirector | Gift G | −6,000 | – | 60,933 | Form 4 |
| 2026-02-19 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,259 | 30.46 | 307,444 | Form 4 |
| 2026-02-19 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +4,440 | 17.16 | 311,884 | Form 4 |
| 2026-02-09 | McGirr David W JDirector | Gift G | −53,400 | – | 44,323 | Form 4 |
| 2026-02-09 | McGirr David W JDirector | Gift G | +53,400 | – | 53,400 | Form 4 |
| 2026-02-09 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +4,440 | 17.16 | 308,322 | Form 4 |
| 2026-02-09 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,259 | 30.46 | 314,581 | Form 4 |
| 2026-02-02 | Flammer Martina M.d.Chief Medical Officer | Option exercise M | +7,982 | 65.72 | 92,889 | Form 4 |
| 2026-01-20 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,259 | 30.46 | 313,150 | Form 4 |
| 2026-01-20 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +4,440 | 17.16 | 317,590 | Form 4 |
| 2026-01-12 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,259 | 30.46 | 321,666 | Form 4 |
| 2026-01-12 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +4,440 | 17.16 | 326,106 | Form 4 |
| 2026-01-06 | Flammer Martina M.d.Chief Medical Officer | Option exercise M | +8,570 | 26.43 | 103,324 | Form 4 |
| 2026-01-05 | Flammer Martina M.d.Chief Medical Officer | Option exercise M | +4,358 | 19.74 | 99,112 | Form 4 |
| 2026-01-05 | Flammer Martina M.d.Chief Medical Officer | Option exercise M | +7,945 | 29.13 | 107,057 | Form 4 |
| 2026-01-02 | Schaeffer Orlov S NicoleChief People Strategy Officer | Grant or award A | +5,293 | – | 41,754 | Form 4 |
| 2026-01-02 | Schaeffer Orlov S NicoleChief People Strategy Officer | Option exercise M | +87,290 | 13.91 | 129,044 | Form 4 |
| 2026-01-02 | Lewis WilliamDirector, Chair and CEO | Grant or award A | +21,172 | – | 325,083 | Form 4 |
| 2026-01-02 | Bonstein SaraChief Financial Officer | Grant or award A | +5,998 | – | 79,503 | Form 4 |
| 2026-01-02 | Bonstein SaraChief Financial Officer | Grant or award A | +5,645 | – | 85,148 | Form 4 |
| 2026-01-02 | Adsett RogerChief Operating Officer | Grant or award A | +5,998 | – | 111,891 | Form 4 |
| 2026-01-02 | Flammer Martina M.d.Chief Medical Officer | Grant or award A | +5,998 | – | 89,109 | Form 4 |
| 2026-01-02 | Flammer Martina M.d.Chief Medical Officer | Grant or award A | +5,645 | – | 94,754 | Form 4 |
| 2026-01-02 | Smith Michael AlexanderChief Legal Officer | Grant or award A | +5,293 | – | 60,195 | Form 4 |
| 2025-12-18 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +4,440 | 17.16 | 308,351 | Form 4 |
| 2025-12-18 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,259 | 30.46 | 314,610 | Form 4 |
| 2025-12-04 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,259 | 30.46 | 310,170 | Form 4 |
| 2025-12-04 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +4,440 | 17.16 | 314,610 | Form 4 |
| 2025-12-01 | Flammer Martina M.d.Chief Medical Officer | Option exercise M | +8,895 | 25.83 | 92,006 | Form 4 |
| 2025-11-12 | Schaeffer Orlov S NicoleChief People Strategy Officer | Option exercise M | +30,000 | 26.46 | 66,461 | Form 4 |
| 2025-11-11 | Flammer Martina M.d.Chief Medical Officer | Option exercise M | +12,949 | 17.07 | 96,060 | Form 4 |
| 2025-11-11 | Flammer Martina M.d.Chief Medical Officer | Option exercise M | +18,277 | 18.95 | 114,337 | Form 4 |
| 2025-11-06 | Brennan David RDirector | Gift G | −60,000 | – | 66,933 | Form 4 |
| 2025-11-06 | Brennan David RDirector | Gift G | +60,000 | – | 60,000 | Form 4 |
| 2025-11-03 | Smith Michael AlexanderChief Legal Officer | Option exercise M | +27,130 | 23.75 | 82,032 | Form 4 |
| 2025-09-12 | Schaeffer Orlov S NicoleChief People Strategy Officer | Option exercise M | +56,520 | 23.75 | 112,981 | Form 4 |
| 2025-09-11 | Sharoky Melvin MDDirector | Gift G | −2,000 | – | 272,516 | Form 4 |
| 2025-09-11 | Sharoky Melvin MDDirector | Gift G | −159 | – | 741 | Form 4 |
| 2025-09-11 | Sharoky Melvin MDDirector | Gift G | +159 | – | 272,675 | Form 4 |
| 2025-09-04 | Schaeffer Orlov S NicoleChief People Strategy Officer | Gift G | −23,303 | – | 56,461 | Form 4 |
| 2025-09-02 | Flammer Martina M.d.Chief Medical Officer | Option exercise M | +13,680 | 34.03 | 96,791 | Form 4 |
| 2025-09-02 | Flammer Martina M.d.Chief Medical Officer | Option exercise M | +17,160 | 26.46 | 113,951 | Form 4 |
| 2025-09-02 | Flammer Martina M.d.Chief Medical Officer | Option exercise M | +25,710 | 26.43 | 139,661 | Form 4 |
| 2025-09-02 | Flammer Martina M.d.Chief Medical Officer | Option exercise M | +38,846 | 17.07 | 178,507 | Form 4 |
| 2025-09-02 | Flammer Martina M.d.Chief Medical Officer | Option exercise M | +13,072 | 19.74 | 191,579 | Form 4 |
| 2025-09-02 | Flammer Martina M.d.Chief Medical Officer | Option exercise M | +36,555 | 18.95 | 228,134 | Form 4 |
| 2025-09-02 | Flammer Martina M.d.Chief Medical Officer | Option exercise M | +23,835 | 29.13 | 251,969 | Form 4 |
| 2025-09-02 | Flammer Martina M.d.Chief Medical Officer | Option exercise M | +17,790 | 25.83 | 269,759 | Form 4 |
| 2025-09-02 | Smith Michael AlexanderChief Legal Officer | Option exercise M | +12,780 | 30.46 | 79,174 | Form 4 |
| 2025-08-18 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,865 | 10.85 | 240,789 | Form 4 |
| 2025-08-13 | Sharoky Melvin MDDirector | Gift G | −6,100 | – | 284,516 | Form 4 |
| 2025-08-13 | Sharoky Melvin MDDirector | Gift G | −15,000 | – | 900 | Form 4 |
| 2025-08-13 | Sharoky Melvin MDDirector | Gift G | +5,000 | – | 6,847 | Form 4 |
| 2025-08-04 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,830 | 10.85 | 240,754 | Form 4 |
| 2025-08-04 | Flammer Martina M.d.Chief Medical Officer | Option exercise M | +8,715 | 19.74 | 91,826 | Form 4 |
| 2025-07-21 | Bonstein SaraChief Financial Officer | Option exercise M | +3,443 | 26.46 | 87,460 | Form 4 |
| 2025-07-21 | Bonstein SaraChief Financial Officer | Option exercise M | +11,455 | 28.88 | 98,915 | Form 4 |
| 2025-07-21 | Bonstein SaraChief Financial Officer | Option exercise M | +15,890 | 29.13 | 114,805 | Form 4 |
| 2025-07-21 | Bonstein SaraChief Financial Officer | Option exercise M | +17,100 | 34.03 | 131,905 | Form 4 |
| 2025-07-15 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,830 | 10.85 | 240,754 | Form 4 |
| 2025-07-07 | Bonstein SaraChief Financial Officer | Option exercise M | +6,244 | 19.74 | 100,137 | Form 4 |
| 2025-07-07 | Bonstein SaraChief Financial Officer | Option exercise M | +4,362 | 24.70 | 104,499 | Form 4 |
| 2025-07-07 | Bonstein SaraChief Financial Officer | Option exercise M | +23,565 | 26.43 | 128,064 | Form 4 |
| 2025-07-07 | Bonstein SaraChief Financial Officer | Option exercise M | +13,717 | 26.46 | 141,781 | Form 4 |
| 2025-07-01 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,830 | 10.85 | 240,754 | Form 4 |
| 2025-06-23 | Bonstein SaraChief Financial Officer | Option exercise M | +35,253 | 18.95 | 138,665 | Form 4 |
| 2025-06-23 | Bonstein SaraChief Financial Officer | Option exercise M | +12,636 | 19.74 | 151,301 | Form 4 |
| 2025-06-16 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +129,805 | 10.85 | 363,729 | Form 4 |
| 2025-06-11 | Schaeffer Orlov S NicoleChief People Strategy Officer | Option exercise M | +70,000 | 13.91 | 188,579 | Form 4 |
| 2025-06-11 | Flammer Martina M.d.Chief Medical Officer | Option exercise M | +19,423 | 17.07 | 102,534 | Form 4 |
| 2025-06-10 | Bonstein SaraChief Financial Officer | Option exercise M | +24,150 | 18.95 | 137,438 | Form 4 |
| 2025-06-10 | Bonstein SaraChief Financial Officer | Option exercise M | +23,740 | 17.07 | 161,178 | Form 4 |
| 2025-06-10 | Schaeffer Orlov S NicoleChief People Strategy Officer | Option exercise M | +38,300 | 17.16 | 156,879 | Form 4 |
| 2025-06-10 | Flammer Martina M.d.Chief Medical Officer | Option exercise M | +25,740 | 26.46 | 108,851 | Form 4 |
| 2025-06-02 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,830 | 10.85 | 240,754 | Form 4 |
| 2025-05-27 | Sharoky Melvin MDDirector | Gift G | −200 | – | 300,616 | Form 4 |
| 2025-05-20 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,830 | 10.85 | 240,754 | Form 4 |
| 2025-05-20 | Sharoky Melvin MDDirector | Gift G | −400 | – | 300,816 | Form 4 |
| 2025-05-20 | Sharoky Melvin MDDirector | Gift G | +100 | – | 100 | Form 4 |
| 2025-05-20 | Sharoky Melvin MDDirector | Gift G | +100 | – | 100 | Form 4 |
| 2025-05-20 | Sharoky Melvin MDDirector | Gift G | +100 | – | 100 | Form 4 |
| 2025-05-20 | Sharoky Melvin MDDirector | Gift G | +100 | – | 100 | Form 4 |
| 2025-05-15 | Lee LeoDirector | Grant or award A | +5,058 | – | 129,677 | Form 4 |
| 2025-05-15 | McGirr David W JDirector | Grant or award A | +5,058 | – | 103,973 | Form 4 |
| 2025-05-15 | Anderson Elizabeth MDirector | Grant or award A | +5,058 | – | 73,729 | Form 4 |
| 2025-05-15 | Sharoky Melvin MDDirector | Grant or award A | +5,058 | – | 301,216 | Form 4 |
| 2025-05-15 | Desjardins ClarissaDirector | Grant or award A | +5,058 | – | 67,007 | Form 4 |
| 2025-05-15 | Schafer CarolDirector | Grant or award A | +5,058 | – | 63,317 | Form 4 |
| 2025-05-15 | Brennan David RDirector | Grant or award A | +5,058 | – | 126,933 | Form 4 |
| 2025-05-15 | Smith Michael AlexanderChief Legal Officer | Grant or award A | +5,578 | – | 97,372 | Form 4 |
| 2025-05-15 | Flammer Martina M.d.Chief Medical Officer | Grant or award A | +6,508 | – | 96,521 | Form 4 |
| 2025-05-15 | Lewis WilliamDirector, Chair and CEO | Grant or award A | +22,314 | – | 335,287 | Form 4 |
| 2025-05-15 | Schaeffer Orlov S NicoleChief People Strategy Officer | Grant or award A | +5,578 | – | 120,221 | Form 4 |
| 2025-05-15 | Adsett RogerChief Operating Officer | Grant or award A | +6,508 | – | 143,183 | Form 4 |
| 2025-05-15 | Bonstein SaraChief Financial Officer | Grant or award A | +6,508 | – | 114,867 | Form 4 |
| 2025-05-14 | Sharoky Melvin MDDirector | Gift G | −576 | – | 296,158 | Form 4 |
| 2025-05-14 | Sharoky Melvin MDDirector | Gift G | +576 | – | 576 | Form 4 |
| 2025-05-01 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,830 | 10.85 | 240,754 | Form 4 |
| 2025-04-15 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,830 | 10.85 | 240,754 | Form 4 |
| 2025-04-01 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,830 | 10.85 | 240,754 | Form 4 |
| 2025-03-17 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +18,750 | 22.76 | 352,936 | Form 4 |
| 2025-03-17 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,830 | 10.85 | 240,754 | Form 4 |
| 2025-03-03 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +18,750 | 22.76 | 352,936 | Form 4 |
| 2025-03-03 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,830 | 10.85 | 240,754 | Form 4 |
| 2025-02-25 | Sharoky Melvin MDDirector | Gift G | −1,443 | – | 296,734 | Form 4 |
| 2025-02-25 | Sharoky Melvin MDDirector | Gift G | +481 | – | 5,180 | Form 4 |
| 2025-02-25 | Sharoky Melvin MDDirector | Gift G | +481 | – | 3,481 | Form 4 |
| 2025-02-25 | Sharoky Melvin MDDirector | Gift G | +481 | – | 4,764 | Form 4 |
| 2025-02-18 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +18,750 | 22.76 | 352,936 | Form 4 |
| 2025-02-18 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,830 | 10.85 | 240,754 | Form 4 |
| 2025-02-05 | Smith Michael AlexanderChief Legal Officer | Grant or award A | +47,295 | – | 117,260 | Form 4 |
| 2025-02-05 | Bonstein SaraChief Financial Officer | Grant or award A | +65,033 | – | 183,896 | Form 4 |
| 2025-02-05 | Wise John DraytonChief Commercial Officer | Grant or award A | +15,373 | – | 140,935 | Form 4 |
| 2025-02-05 | Lewis WilliamDirector, Chair and CEO | Grant or award A | +153,710 | – | 533,244 | Form 4 |
| 2025-02-05 | Adsett RogerChief Operating Officer | Grant or award A | +88,680 | – | 234,762 | Form 4 |
| 2025-02-05 | Schaeffer Orlov S NicoleChief People Strategy Officer | Grant or award A | +47,295 | – | 144,378 | Form 4 |
| 2025-02-05 | Flammer Martina M.d.Chief Medical Officer | Grant or award A | +70,943 | – | 171,108 | Form 4 |
| 2025-02-03 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +18,750 | 22.76 | 398,284 | Form 4 |
| 2025-02-03 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,830 | 10.85 | 240,754 | Form 4 |
| 2025-01-30 | Schaeffer Orlov S NicoleChief People Strategy Officer | Option exercise M | +50,000 | 16.16 | 147,083 | Form 4 |
| 2025-01-30 | Schaeffer Orlov S NicoleChief People Strategy Officer | Option exercise M | +41,140 | 13.67 | 188,223 | Form 4 |
| 2025-01-15 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +18,750 | 22.76 | 411,339 | Form 4 |
| 2025-01-15 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,830 | 10.85 | 240,754 | Form 4 |
| 2025-01-08 | Adsett RogerChief Operating Officer | Grant or award A | +6,657 | – | 152,441 | Form 4 |
| 2025-01-08 | Smith Michael AlexanderChief Legal Officer | Grant or award A | +5,706 | – | 70,284 | Form 4 |
| 2025-01-08 | Lewis WilliamDirector, Chair and CEO | Grant or award A | +22,824 | – | 395,567 | Form 4 |
| 2025-01-08 | Wise John DraytonChief Commercial Officer | Grant or award A | +6,657 | – | 125,849 | Form 4 |
| 2025-01-08 | Schaeffer Orlov S NicoleChief People Strategy Officer | Grant or award A | +5,706 | – | 102,012 | Form 4 |
| 2025-01-08 | Bonstein SaraChief Financial Officer | Grant or award A | +6,657 | – | 119,929 | Form 4 |
| 2025-01-08 | Flammer Martina M.d.Chief Medical Officer | Grant or award A | +6,657 | – | 107,721 | Form 4 |
| 2025-01-07 | Wise John DraytonChief Commercial Officer | Option exercise M | +10,000 | 16.07 | 132,492 | Form 4 |
| 2025-01-02 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +18,750 | 22.76 | 403,710 | Form 4 |
| 2025-01-02 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,830 | 10.85 | 240,754 | Form 4 |
| 2024-12-19 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +18,750 | 22.76 | 403,710 | Form 4 |
| 2024-12-19 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,830 | 10.85 | 240,754 | Form 4 |
| 2024-12-12 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +18,750 | 22.76 | 403,710 | Form 4 |
| 2024-12-12 | Lewis WilliamDirector, Chair and CEO | Option exercise M | +6,830 | 10.85 | 240,754 | Form 4 |
How to read it
- Buy, sale
- Code P and S on the form: shares bought or sold in the market, at the market price. The other codes are mostly pay (a grant, an option exercised) or tax (shares the company withheld), and say little about what the insider thinks of the price.
- Plan
- A sale or purchase under a Rule 10b5-1 plan, set up in advance and running on its own schedule. Since April 2023 the form has a box for it. Much executive selling is planned and says more about diversifying than about the company.
- Holds after
- The shares the insider still held after the trade, in the form the trade was in (directly, or indirectly through a trust or a fund).
- Value
- Shares times the price the form reports, which is often an average over several fills on the day.
Read from the SEC's own quarterly data sets of Forms 3, 4 and 5, and from each day's filings since the last one. A correcting amendment replaces the lines it restates. Every row links to its filing. None of this is advice: insiders sell for many reasons, and buy for fewer.