Axsome Therapeutics, Inc. (AXSM) · Insider trading
What Axsome Therapeutics's directors, officers and largest holders bought and sold themselves, from the Form 4 each of them files with the SEC within two business days of a trade. Open-market purchases and sales first: those are the trades somebody chose to make at the market price.
Bought, 12 months
$0
0 insiders, 0 trades
Sold, 12 months
$134.33M
8 insiders, 100% under a plan
Net, 12 months
−$134.33M
bought less sold
Latest filing
2026-09-03
filings read to 2026-10-19
Who traded, two years
| Insider | Bought | Sold | Trades | Last trade | Holds after |
|---|---|---|---|---|---|
| Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | – | $110.58M | 20 | 2026-08-06 | 7,229 |
| Jacobson Mark L.Chief Operating Officer | – | $22.29M | 10 | 2026-09-03 | 0 |
| Jeffs RogerDirector | – | $13.52M | 8 | 2026-06-11 | 58,367 |
| Pizzie NickChief Financial Officer | – | $12.13M | 4 | 2026-06-09 | 42,867 |
| Coleman MarkDirector | $200,466 | $9.31M | 11 | 2026-06-10 | 30,389 |
| Saad Mark EDirector | – | $7.35M | 3 | 2025-12-31 | 10,002 |
| Murdock Hunter R.General Counsel | – | $3.65M | 5 | 2025-06-23 | 0 |
| Maizel AriChief Commercial Officer | – | $2.75M | 2 | 2026-04-22 | 0 |
| Mahony SusanDirector | – | $145,017 | 2 | 2026-06-10 | 829 |
Open-market purchases and sales
Newest first. “Plan” marks a trade made under a 10b5-1 plan set up in advance.
| Date | Insider | Trade | Shares | Price | Value | Holds after | Filing |
|---|---|---|---|---|---|---|---|
| 2026-09-03 | Jacobson Mark L.Chief Operating Officer | Saleplan | 10,000 | 208.65 | $2.09M | 0 | Form 4 |
| 2026-08-06 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Saleplan | 4,660 | 213.95 | $997,007 | 7,229 | Form 4 |
| 2026-08-05 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Saleplan | 45,004 | 212.01 | $9.54M | 7,229 | Form 4 |
| 2026-07-01 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Saleplan | 49,666 | 240.25 | $11.93M | 7,229 | Form 4 |
| 2026-06-11 | Jeffs RogerDirector | Saleplan | 286 | 249.12 | $71,248 | 58,367 | Form 4 |
| 2026-06-10 | Jeffs RogerDirector | Saleplan | 286 | 246.18 | $70,407 | 58,653 | Form 4 |
| 2026-06-10 | Coleman MarkDirector | Saleplan | 643 | 249.00 | $160,107 | 30,389 | Form 4 |
| 2026-06-10 | Mahony SusanDirector | Saleplan | 300 | 246.18 | $73,854 | 829 | Form 4 |
| 2026-06-09 | Mahony SusanDirector | Saleplan | 300 | 237.21 | $71,163 | 1,129 | Form 4 |
| 2026-06-09 | Pizzie NickChief Financial Officer | Saleplan | 33,000 | 240.09 | $7.92M | 42,867 | Form 4 |
| 2026-06-09 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Saleplan | 49,670 | 241.01 | $11.97M | 7,229 | Form 4 |
| 2026-06-02 | Coleman MarkDirector | Saleplan | 5,537 | 223.39 | $1.24M | 29,603 | Form 4 |
| 2026-06-01 | Coleman MarkDirector | Saleplan | 6,000 | 230.30 | $1.38M | 35,140 | Form 4 |
| 2026-05-29 | Coleman MarkDirector | Saleplan | 6,000 | 233.46 | $1.40M | 41,140 | Form 4 |
| 2026-05-05 | Jacobson Mark L.Chief Operating Officer | Saleplan | 233 | 228.18 | $53,166 | 0 | Form 4 |
| 2026-05-04 | Jacobson Mark L.Chief Operating Officer | Saleplan | 4,517 | 227.94 | $1.03M | 0 | Form 4 |
| 2026-04-22 | Maizel AriChief Commercial Officer | Saleplan | 7,500 | 182.42 | $1.37M | 0 | Form 4 |
| 2026-02-26 | Jacobson Mark L.Chief Operating Officer | Saleplan | 35,378 | 161.88 | $5.73M | 0 | Form 4 |
| 2026-02-26 | Coleman MarkDirector | Saleplan | 25,000 | 161.11 | $4.03M | 47,140 | Form 4 |
| 2026-02-02 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Saleplan | 32,410 | 185.60 | $6.02M | 7,229 | Form 4 |
| 2026-01-22 | Pizzie NickChief Financial Officer | Saleplan | 12,000 | 187.92 | $2.26M | 42,588 | Form 4 |
| 2026-01-21 | Maizel AriChief Commercial Officer | Saleplan | 7,500 | 184.44 | $1.38M | 0 | Form 4 |
| 2026-01-07 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Saleplan | 31,261 | 170.38 | $5.33M | 7,229 | Form 4 |
| 2026-01-06 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Saleplan | 29,450 | 172.33 | $5.08M | 7,229 | Form 4 |
| 2026-01-05 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Saleplan | 78,703 | 171.28 | $13.48M | 7,229 | Form 4 |
| 2025-12-31 | Saad Mark EDirector | Saleplan | 6,231 | 165.18 | $1.03M | 10,002 | Form 4 |
| 2025-12-31 | Saad Mark EDirector | Saleplan | 31,346 | 165.18 | $5.18M | 10,002 | Form 4 |
| 2025-12-04 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Saleplan | 10,558 | 148.18 | $1.56M | 7,229 | Form 4 |
| 2025-12-03 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Saleplan | 20,163 | 146.94 | $2.96M | 7,229 | Form 4 |
| 2025-12-02 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Saleplan | 49,252 | 144.59 | $7.12M | 7,229 | Form 4 |
| 2025-11-05 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Saleplan | 21,775 | 134.49 | $2.93M | 7,229 | Form 4 |
| 2025-11-04 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Saleplan | 50,459 | 133.79 | $6.75M | 7,229 | Form 4 |
| 2025-11-03 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Saleplan | 91,705 | 132.34 | $12.14M | 7,229 | Form 4 |
| 2025-10-08 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Saleplan | 12,774 | 118.84 | $1.52M | 7,229 | Form 4 |
| 2025-10-07 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Saleplan | 13,390 | 118.77 | $1.59M | 7,229 | Form 4 |
| 2025-10-06 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Saleplan | 19,220 | 120.17 | $2.31M | 7,229 | Form 4 |
| 2025-09-22 | Jacobson Mark L.Chief Operating Officer | Saleplan | 10,000 | 115.96 | $1.16M | 0 | Form 4 |
| 2025-09-16 | Jacobson Mark L.Chief Operating Officer | Saleplan | 5,783 | 116.19 | $671,927 | 0 | Form 4 |
| 2025-09-16 | Jacobson Mark L.Chief Operating Officer | Saleplan | 40,000 | 114.23 | $4.57M | 0 | Form 4 |
| 2025-09-16 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Saleplan | 19,719 | 114.19 | $2.25M | 7,229 | Form 4 |
25 more
| 2025-09-15 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Saleplan | 15,254 | 117.37 | $1.79M | 7,229 | Form 4 |
| 2025-09-12 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Saleplan | 27,907 | 118.96 | $3.32M | 7,229 | Form 4 |
| 2025-09-08 | Coleman MarkDirector | Buy | 800 | 127.20 | $101,760 | 47,437 | Form 4 |
| 2025-09-08 | Coleman MarkDirector | Buy | 287 | 127.30 | $36,535 | 47,724 | Form 4 |
| 2025-09-08 | Coleman MarkDirector | Buy | 488 | 127.40 | $62,171 | 48,212 | Form 4 |
| 2025-09-05 | Saad Mark EDirector | Saleplan | 9,127 | 125.07 | $1.14M | 10,002 | Form 4 |
| 2025-09-02 | Jeffs RogerDirector | Saleplan | 13,464 | 123.68 | $1.67M | 57,510 | Form 4 |
| 2025-08-29 | Jeffs RogerDirector | Saleplan | 20,000 | 121.27 | $2.43M | 70,974 | Form 4 |
| 2025-08-28 | Jeffs RogerDirector | Saleplan | 20,000 | 121.60 | $2.43M | 90,974 | Form 4 |
| 2025-08-27 | Jeffs RogerDirector | Saleplan | 20,000 | 122.30 | $2.45M | 110,974 | Form 4 |
| 2025-08-26 | Jeffs RogerDirector | Saleplan | 20,000 | 120.03 | $2.40M | 130,974 | Form 4 |
| 2025-08-22 | Jeffs RogerDirector | Saleplan | 16,694 | 120.08 | $2.00M | 150,974 | Form 4 |
| 2025-06-23 | Murdock Hunter R.General Counsel | Saleplan | 6,014 | 100.12 | $602,122 | 0 | Form 4 |
| 2025-06-20 | Murdock Hunter R.General Counsel | Saleplan | 7,500 | 102.47 | $768,525 | 0 | Form 4 |
| 2025-06-18 | Murdock Hunter R.General Counsel | Saleplan | 7,500 | 100.90 | $756,750 | 0 | Form 4 |
| 2025-06-17 | Murdock Hunter R.General Counsel | Saleplan | 7,500 | 100.26 | $751,950 | 0 | Form 4 |
| 2025-06-16 | Murdock Hunter R.General Counsel | Saleplan | 7,500 | 102.42 | $768,150 | 0 | Form 4 |
| 2025-06-09 | Jacobson Mark L.Chief Operating Officer | Saleplan | 25,000 | 110.44 | $2.76M | 5,783 | Form 4 |
| 2025-05-28 | Coleman MarkDirector | Saleplan | 3,750 | 103.43 | $387,862 | 46,637 | Form 4 |
| 2025-05-28 | Jacobson Mark L.Chief Operating Officer | Saleplan | 20,000 | 103.45 | $2.07M | 5,783 | Form 4 |
| 2025-05-27 | Coleman MarkDirector | Saleplan | 3,750 | 105.47 | $395,512 | 50,387 | Form 4 |
| 2025-05-27 | Jacobson Mark L.Chief Operating Officer | Saleplan | 20,673 | 104.66 | $2.16M | 5,783 | Form 4 |
| 2025-05-20 | Coleman MarkDirector | Sale | 3,000 | 107.49 | $322,470 | 54,137 | Form 4 |
| 2025-02-14 | Pizzie NickChief Financial Officer | Saleplan | 3,000 | 131.07 | $393,210 | 42,187 | Form 4 |
| 2025-02-13 | Pizzie NickChief Financial Officer | Saleplan | 12,000 | 129.86 | $1.56M | 42,187 | Form 4 |
Grants, exercises and other transactions
Pay, tax and paperwork rather than a choice to trade at the market price. Two years.
53 × option exercise
Show them
| Date | Insider | What | Shares | Price | Holds after | Filing |
|---|---|---|---|---|---|---|
| 2026-09-03 | Jacobson Mark L.Chief Operating Officer | Option exercise M | +10,000 | 12.95 | 10,000 | Form 4 |
| 2026-08-06 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Option exercise M | +4,660 | 4.95 | 11,889 | Form 4 |
| 2026-08-05 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Option exercise M | +45,004 | 4.95 | 52,233 | Form 4 |
| 2026-07-01 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Option exercise M | +49,666 | 4.95 | 56,895 | Form 4 |
| 2026-06-09 | Pizzie NickChief Financial Officer | Option exercise M | +33,000 | 3.50 | 75,867 | Form 4 |
| 2026-06-09 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Option exercise M | +49,670 | 4.95 | 56,899 | Form 4 |
| 2026-06-08 | Coleman MarkDirector | Option exercise M | +1,429 | – | 31,032 | Form 4 |
| 2026-06-08 | Mahony SusanDirector | Option exercise M | +1,429 | – | 1,429 | Form 4 |
| 2026-06-08 | Saad Mark EDirector | Option exercise M | +1,429 | – | 11,431 | Form 4 |
| 2026-06-08 | Jeffs RogerDirector | Option exercise M | +1,429 | – | 58,939 | Form 4 |
| 2026-05-05 | Jacobson Mark L.Chief Operating Officer | Option exercise M | +233 | 12.95 | 233 | Form 4 |
| 2026-05-04 | Jacobson Mark L.Chief Operating Officer | Option exercise M | +4,517 | 12.95 | 4,517 | Form 4 |
| 2026-04-22 | Maizel AriChief Commercial Officer | Option exercise M | +7,500 | 70.73 | 7,500 | Form 4 |
| 2026-02-26 | Jacobson Mark L.Chief Operating Officer | Option exercise M | +35,378 | 2.85 | 35,378 | Form 4 |
| 2026-02-23 | Coleman MarkDirector | Option exercise M | +6,250 | 4.95 | 72,140 | Form 4 |
| 2026-02-20 | Coleman MarkDirector | Option exercise M | +12,485 | 4.95 | 65,890 | Form 4 |
| 2026-02-10 | Coleman MarkDirector | Option exercise M | +5,193 | 8.02 | 53,405 | Form 4 |
| 2026-02-02 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Option exercise M | +32,410 | 8.02 | 39,639 | Form 4 |
| 2026-01-22 | Pizzie NickChief Financial Officer | Option exercise M | +12,000 | 3.50 | 54,588 | Form 4 |
| 2026-01-21 | Maizel AriChief Commercial Officer | Option exercise M | +7,500 | 70.73 | 7,500 | Form 4 |
| 2026-01-07 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Option exercise M | +31,261 | 8.02 | 38,490 | Form 4 |
| 2026-01-06 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Option exercise M | +29,450 | 8.02 | 36,679 | Form 4 |
| 2026-01-05 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Option exercise M | +78,703 | 8.02 | 85,932 | Form 4 |
| 2025-12-31 | Saad Mark EDirector | Option exercise M | +6,231 | 8.02 | 16,233 | Form 4 |
| 2025-12-31 | Saad Mark EDirector | Option exercise M | +31,346 | 4.95 | 41,348 | Form 4 |
| 2025-12-04 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Option exercise M | +10,558 | 8.02 | 17,787 | Form 4 |
| 2025-12-03 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Option exercise M | +20,163 | 8.02 | 27,392 | Form 4 |
| 2025-12-02 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Option exercise M | +49,252 | 8.02 | 56,481 | Form 4 |
| 2025-11-05 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Option exercise M | +21,775 | 8.02 | 29,004 | Form 4 |
| 2025-11-04 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Option exercise M | +50,459 | 8.02 | 57,688 | Form 4 |
| 2025-11-03 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Option exercise M | +91,705 | 8.02 | 98,934 | Form 4 |
| 2025-10-08 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Option exercise M | +12,774 | 8.02 | 20,003 | Form 4 |
| 2025-10-07 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Option exercise M | +13,390 | 8.02 | 20,619 | Form 4 |
| 2025-10-06 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Option exercise M | +19,220 | 8.02 | 26,449 | Form 4 |
| 2025-09-22 | Jacobson Mark L.Chief Operating Officer | Option exercise M | +10,000 | 2.85 | 10,000 | Form 4 |
| 2025-09-16 | Jacobson Mark L.Chief Operating Officer | Option exercise M | +25,000 | 4.95 | 25,000 | Form 4 |
| 2025-09-16 | Jacobson Mark L.Chief Operating Officer | Option exercise M | +15,000 | 4.85 | 40,000 | Form 4 |
| 2025-09-16 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Option exercise M | +19,719 | 8.02 | 26,948 | Form 4 |
| 2025-09-15 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Option exercise M | +15,254 | 8.02 | 22,483 | Form 4 |
| 2025-09-12 | Tabuteau HerriotDirector, Chief Executive Officer, 10% owner | Option exercise M | +27,907 | 8.02 | 35,136 | Form 4 |
| 2025-09-05 | Saad Mark EDirector | Option exercise M | +9,127 | 9.00 | 19,129 | Form 4 |
| 2025-06-23 | Murdock Hunter R.General Counsel | Option exercise M | +6,014 | 29.91 | 6,014 | Form 4 |
| 2025-06-20 | Murdock Hunter R.General Counsel | Option exercise M | +7,500 | 29.91 | 7,500 | Form 4 |
| 2025-06-18 | Murdock Hunter R.General Counsel | Option exercise M | +7,500 | 29.91 | 7,500 | Form 4 |
| 2025-06-17 | Murdock Hunter R.General Counsel | Option exercise M | +7,500 | 29.91 | 7,500 | Form 4 |
| 2025-06-16 | Murdock Hunter R.General Counsel | Option exercise M | +7,500 | 29.91 | 7,500 | Form 4 |
| 2025-06-09 | Jacobson Mark L.Chief Operating Officer | Option exercise M | +25,000 | 8.02 | 30,783 | Form 4 |
| 2025-05-28 | Jacobson Mark L.Chief Operating Officer | Option exercise M | +20,000 | 6.47 | 25,783 | Form 4 |
| 2025-05-27 | Jacobson Mark L.Chief Operating Officer | Option exercise M | +20,673 | 6.47 | 26,456 | Form 4 |
| 2025-02-14 | Pizzie NickChief Financial Officer | Option exercise M | +3,000 | 3.50 | 45,187 | Form 4 |
| 2025-02-13 | Pizzie NickChief Financial Officer | Option exercise M | +12,000 | 3.50 | 54,187 | Form 4 |
| 2025-01-03 | Coleman MarkDirector | Option exercise M | +9,127 | 9.00 | 57,137 | Form 4 |
| 2024-11-19 | Coleman MarkDirector | Option exercise M | +33,410 | 5.94 | 48,010 | Form 4 |
How to read it
- Buy, sale
- Code P and S on the form: shares bought or sold in the market, at the market price. The other codes are mostly pay (a grant, an option exercised) or tax (shares the company withheld), and say little about what the insider thinks of the price.
- Plan
- A sale or purchase under a Rule 10b5-1 plan, set up in advance and running on its own schedule. Since April 2023 the form has a box for it. Much executive selling is planned and says more about diversifying than about the company.
- Holds after
- The shares the insider still held after the trade, in the form the trade was in (directly, or indirectly through a trust or a fund).
- Value
- Shares times the price the form reports, which is often an average over several fills on the day.
Read from the SEC's own quarterly data sets of Forms 3, 4 and 5, and from each day's filings since the last one. A correcting amendment replaces the lines it restates. Every row links to its filing. None of this is advice: insiders sell for many reasons, and buy for fewer.