Arrowhead Pharmaceuticals, Inc. (ARWR) · Insider trading
What Arrowhead Pharmaceuticals's directors, officers and largest holders bought and sold themselves, from the Form 4 each of them files with the SEC within two business days of a trade. Open-market purchases and sales first: those are the trades somebody chose to make at the market price.
Bought, 12 months
$0
0 insiders, 0 trades
Sold, 12 months
$37.34M
10 insiders, 45% under a plan
Net, 12 months
−$37.34M
bought less sold
Latest filing
2026-08-20
filings read to 2026-10-19
Who traded, two years
| Insider | Bought | Sold | Trades | Last trade | Holds after |
|---|---|---|---|---|---|
| Anzalone Christopher RichardDirector, Chief Executive Officer | – | $32.63M | 38 | 2026-01-02 | 3,798,510 |
| Hamilton James CChief Medical Officer | – | $6.30M | 16 | 2026-04-23 | 226,958 |
| O'Brien PatrickCOO | – | $3.86M | 15 | 2026-01-05 | 520,033 |
| Perry Michael SDirector | – | $2.00M | 2 | 2026-08-18 | 111,459 |
| Ferrari MauroDirector | – | $1.02M | 2 | 2025-12-26 | 69,053 |
| Apel Daniel JosephChief Financial Officer | – | $934,285 | 3 | 2026-04-22 | 172,792 |
| Olukotun Adeoye yDirector | – | $927,682 | 6 | 2026-08-18 | 31,600 |
| Myszkowski Kenneth AllenChief Financial Officer | – | $893,095 | 4 | 2025-01-07 | 465,433 |
| Vakiener VictoriaDirector | – | $876,550 | 4 | 2025-12-19 | 42,964 |
| Waddill William D.Director | – | $730,703 | 5 | 2025-12-19 | 62,514 |
| Lu HongboDirector | – | $228,334 | 1 | 2026-05-12 | 52,012 |
| Given Douglas BDirector | – | $121,556 | 2 | 2024-12-17 | 124,167 |
Open-market purchases and sales
Newest first. “Plan” marks a trade made under a 10b5-1 plan set up in advance.
| Date | Insider | Trade | Shares | Price | Value | Holds after | Filing |
|---|---|---|---|---|---|---|---|
| 2026-08-18 | Olukotun Adeoye yDirector | Sale | 2,000 | 86.96 | $173,920 | 31,600 | Form 4 |
| 2026-08-18 | Perry Michael SDirector | Sale | 11,600 | 87.30 | $1.01M | 111,459 | Form 4 |
| 2026-05-12 | Lu HongboDirector | Saleplan | 2,970 | 76.88 | $228,334 | 52,012 | Form 4 |
| 2026-04-23 | Hamilton James CChief Medical Officer | Saleplan | 10,000 | 75.00 | $750,000 | 226,958 | Form 4 |
| 2026-04-22 | Apel Daniel JosephChief Financial Officer | Saleplan | 3,208 | 70.11 | $224,913 | 172,792 | Form 4 |
| 2026-04-22 | Apel Daniel JosephChief Financial Officer | Saleplan | 1,157 | 70.45 | $81,511 | 171,635 | Form 4 |
| 2026-04-22 | Apel Daniel JosephChief Financial Officer | Saleplan | 8,730 | 71.92 | $627,862 | 162,905 | Form 4 |
| 2026-03-05 | Hamilton James CChief Medical Officer | Saleplan | 10,000 | 64.19 | $641,900 | 236,958 | Form 4 |
| 2026-01-05 | O'Brien PatrickCOO | Saleplan | 4,368 | 61.20 | $267,322 | 520,033 | Form 4 |
| 2026-01-05 | O'Brien PatrickCOO | Saleplan | 6,164 | 62.23 | $383,586 | 513,869 | Form 4 |
| 2026-01-05 | O'Brien PatrickCOO | Saleplan | 13,451 | 62.96 | $846,875 | 500,418 | Form 4 |
| 2026-01-05 | O'Brien PatrickCOO | Saleplan | 11,842 | 63.84 | $755,993 | 488,576 | Form 4 |
| 2026-01-05 | O'Brien PatrickCOO | Saleplan | 2,700 | 64.44 | $173,988 | 485,876 | Form 4 |
| 2026-01-05 | O'Brien PatrickCOO | Saleplan | 900 | 66.01 | $59,409 | 484,976 | Form 4 |
| 2026-01-05 | O'Brien PatrickCOO | Saleplan | 313 | 68.00 | $21,284 | 484,663 | Form 4 |
| 2026-01-05 | O'Brien PatrickCOO | Saleplan | 600 | 61.12 | $36,672 | 484,063 | Form 4 |
| 2026-01-05 | O'Brien PatrickCOO | Saleplan | 900 | 62.25 | $56,025 | 483,163 | Form 4 |
| 2026-01-05 | O'Brien PatrickCOO | Saleplan | 5,873 | 62.91 | $369,470 | 477,290 | Form 4 |
| 2026-01-05 | O'Brien PatrickCOO | Saleplan | 2,336 | 64.04 | $149,597 | 474,954 | Form 4 |
| 2026-01-05 | O'Brien PatrickCOO | Saleplan | 46 | 68.00 | $3,128 | 474,908 | Form 4 |
| 2026-01-05 | Hamilton James CChief Medical Officer | Saleplan | 4,625 | 61.24 | $283,235 | 207,497 | Form 4 |
| 2026-01-05 | Hamilton James CChief Medical Officer | Saleplan | 6,090 | 62.28 | $379,285 | 201,407 | Form 4 |
| 2026-01-05 | Hamilton James CChief Medical Officer | Saleplan | 14,792 | 63.01 | $932,044 | 186,615 | Form 4 |
| 2026-01-05 | Hamilton James CChief Medical Officer | Saleplan | 12,711 | 63.95 | $812,868 | 173,904 | Form 4 |
| 2026-01-05 | Hamilton James CChief Medical Officer | Saleplan | 1,200 | 64.49 | $77,388 | 172,704 | Form 4 |
| 2026-01-05 | Hamilton James CChief Medical Officer | Saleplan | 437 | 65.97 | $28,829 | 172,267 | Form 4 |
| 2026-01-05 | Hamilton James CChief Medical Officer | Saleplan | 309 | 68.00 | $21,012 | 171,958 | Form 4 |
| 2026-01-02 | Anzalone Christopher RichardDirector, Chief Executive Officer | Saleplan | 7,416 | 65.88 | $488,566 | 3,798,510 | Form 4 |
| 2026-01-02 | Anzalone Christopher RichardDirector, Chief Executive Officer | Saleplan | 5,771 | 66.39 | $383,137 | 3,792,739 | Form 4 |
| 2025-12-29 | Anzalone Christopher RichardDirector, Chief Executive Officer | Saleplan | 35,181 | 69.33 | $2.44M | 3,822,471 | Form 4 |
| 2025-12-29 | Anzalone Christopher RichardDirector, Chief Executive Officer | Saleplan | 16,545 | 68.69 | $1.14M | 3,805,926 | Form 4 |
| 2025-12-26 | Ferrari MauroDirector | Saleplan | 7,530 | 70.00 | $527,100 | 69,053 | Form 4 |
| 2025-12-22 | Anzalone Christopher RichardDirector, Chief Executive Officer | Saleplan | 10,012 | 68.33 | $684,120 | 3,808,500 | Form 4 |
| 2025-12-22 | Anzalone Christopher RichardDirector, Chief Executive Officer | Saleplan | 2,574 | 68.85 | $177,220 | 3,805,926 | Form 4 |
| 2025-12-19 | Olukotun Adeoye yDirector | Saleplan | 3,090 | 66.70 | $206,103 | 40,510 | Form 4 |
| 2025-12-19 | Olukotun Adeoye yDirector | Saleplan | 6,083 | 68.04 | $413,887 | 34,427 | Form 4 |
| 2025-12-19 | Olukotun Adeoye yDirector | Saleplan | 827 | 68.48 | $56,633 | 33,600 | Form 4 |
| 2025-12-19 | Anzalone Christopher RichardDirector, Chief Executive Officer | Saleplan | 3,979 | 66.67 | $265,280 | 3,827,978 | Form 4 |
| 2025-12-19 | Anzalone Christopher RichardDirector, Chief Executive Officer | Saleplan | 8,147 | 68.01 | $554,077 | 3,819,831 | Form 4 |
| 2025-12-19 | Anzalone Christopher RichardDirector, Chief Executive Officer | Saleplan | 1,319 | 68.48 | $90,325 | 3,818,512 | Form 4 |
58 more
| 2025-12-19 | Waddill William D.Director | Saleplan | 2,416 | 66.66 | $161,051 | 62,514 | Form 4 |
| 2025-12-19 | Waddill William D.Director | Saleplan | 5,451 | 68.01 | $370,723 | 57,063 | Form 4 |
| 2025-12-19 | Waddill William D.Director | Saleplan | 500 | 68.53 | $34,265 | 56,563 | Form 4 |
| 2025-12-19 | Vakiener VictoriaDirector | Saleplan | 2,799 | 66.63 | $186,497 | 42,964 | Form 4 |
| 2025-12-19 | Vakiener VictoriaDirector | Saleplan | 5,281 | 67.97 | $358,950 | 37,683 | Form 4 |
| 2025-12-19 | Vakiener VictoriaDirector | Saleplan | 1,960 | 68.39 | $134,044 | 35,723 | Form 4 |
| 2025-12-17 | Anzalone Christopher RichardDirector, Chief Executive Officer | Sale | 46,287 | 63.55 | $2.94M | 3,870,670 | Form 4 |
| 2025-12-17 | Anzalone Christopher RichardDirector, Chief Executive Officer | Sale | 35,750 | 64.51 | $2.31M | 3,834,920 | Form 4 |
| 2025-12-17 | Anzalone Christopher RichardDirector, Chief Executive Officer | Sale | 982 | 65.53 | $64,350 | 3,833,938 | Form 4 |
| 2025-12-17 | Anzalone Christopher RichardDirector, Chief Executive Officer | Sale | 1,981 | 66.30 | $131,340 | 3,831,957 | Form 4 |
| 2025-12-16 | Anzalone Christopher RichardDirector, Chief Executive Officer | Sale | 8,416 | 60.51 | $509,252 | 3,962,839 | Form 4 |
| 2025-12-16 | Anzalone Christopher RichardDirector, Chief Executive Officer | Sale | 10,963 | 61.25 | $671,484 | 3,951,876 | Form 4 |
| 2025-12-16 | Anzalone Christopher RichardDirector, Chief Executive Officer | Sale | 14,095 | 62.12 | $875,581 | 3,937,781 | Form 4 |
| 2025-12-16 | Anzalone Christopher RichardDirector, Chief Executive Officer | Sale | 8,476 | 62.94 | $533,479 | 3,929,305 | Form 4 |
| 2025-12-16 | Anzalone Christopher RichardDirector, Chief Executive Officer | Sale | 6,661 | 64.29 | $428,236 | 3,922,644 | Form 4 |
| 2025-12-16 | Anzalone Christopher RichardDirector, Chief Executive Officer | Sale | 1,000 | 64.96 | $64,960 | 3,921,644 | Form 4 |
| 2025-12-16 | Anzalone Christopher RichardDirector, Chief Executive Officer | Sale | 1,300 | 65.77 | $85,501 | 3,920,344 | Form 4 |
| 2025-12-16 | Anzalone Christopher RichardDirector, Chief Executive Officer | Sale | 166 | 66.77 | $11,084 | 3,920,178 | Form 4 |
| 2025-12-16 | Anzalone Christopher RichardDirector, Chief Executive Officer | Sale | 3,221 | 67.87 | $218,609 | 3,916,957 | Form 4 |
| 2025-12-15 | Anzalone Christopher RichardDirector, Chief Executive Officer | Sale | 100,532 | 68.67 | $6.90M | 4,000,723 | Form 4 |
| 2025-12-15 | Anzalone Christopher RichardDirector, Chief Executive Officer | Sale | 21,321 | 69.28 | $1.48M | 3,979,402 | Form 4 |
| 2025-12-15 | Anzalone Christopher RichardDirector, Chief Executive Officer | Sale | 8,147 | 69.96 | $569,964 | 3,971,255 | Form 4 |
| 2025-12-05 | Perry Michael SDirector | Sale | 16,250 | 61.03 | $991,738 | 115,240 | Form 4 |
| 2025-11-28 | Ferrari MauroDirector | Sale | 8,750 | 56.39 | $493,412 | 68,764 | Form 4 |
| 2025-10-01 | Hamilton James CChief Medical Officer | Saleplan | 20,000 | 35.00 | $700,000 | 212,122 | Form 4 |
| 2025-09-12 | Hamilton James CChief Medical Officer | Saleplan | 15,000 | 30.00 | $450,000 | 232,122 | Form 4 |
| 2025-09-02 | Hamilton James CChief Medical Officer | Saleplan | 15,000 | 25.00 | $375,000 | 247,122 | Form 4 |
| 2025-08-15 | Hamilton James CChief Medical Officer | Saleplan | 9,389 | 20.00 | $187,780 | 262,122 | Form 4 |
| 2025-08-13 | Hamilton James CChief Medical Officer | Saleplan | 611 | 20.00 | $12,220 | 271,511 | Form 4 |
| 2025-04-11 | Anzalone Christopher RichardDirector, Chief Executive Officer | Sale | 50,800 | 11.49 | $583,692 | 3,921,255 | Form 4 |
| 2025-04-10 | Anzalone Christopher RichardDirector, Chief Executive Officer | Sale | 50,000 | 10.87 | $543,500 | 3,972,055 | Form 4 |
| 2025-04-09 | Anzalone Christopher RichardDirector, Chief Executive Officer | Sale | 35,305 | 9.93 | $350,579 | 4,027,072 | Form 4 |
| 2025-04-09 | Anzalone Christopher RichardDirector, Chief Executive Officer | Sale | 3,400 | 10.75 | $36,550 | 4,023,672 | Form 4 |
| 2025-04-09 | Anzalone Christopher RichardDirector, Chief Executive Officer | Sale | 1,617 | 11.76 | $19,016 | 4,022,055 | Form 4 |
| 2025-03-13 | Anzalone Christopher RichardDirector, Chief Executive Officer | Sale | 51,425 | 15.07 | $774,975 | 4,062,377 | Form 4 |
| 2025-03-04 | Anzalone Christopher RichardDirector, Chief Executive Officer | Saleplan | 133,333 | 17.02 | $2.27M | 3,773,802 | Form 4 |
| 2025-03-03 | Anzalone Christopher RichardDirector, Chief Executive Officer | Saleplan | 166,667 | 18.03 | $3.01M | 3,907,135 | Form 4 |
| 2025-01-23 | Olukotun Adeoye yDirector | Saleplan | 959 | 21.00 | $20,139 | 35,781 | Form 4 |
| 2025-01-07 | Myszkowski Kenneth AllenChief Financial Officer | Saleplan | 8,000 | 19.70 | $157,600 | 465,433 | Form 4 |
| 2025-01-07 | Myszkowski Kenneth AllenChief Financial Officer | Saleplan | 10,000 | 19.69 | $196,900 | 455,433 | Form 4 |
| 2025-01-07 | O'Brien PatrickCOO and General Counsel | Saleplan | 8,000 | 19.69 | $157,520 | 527,201 | Form 4 |
| 2025-01-06 | Myszkowski Kenneth AllenChief Financial Officer | Saleplan | 17,765 | 19.68 | $349,615 | 482,835 | Form 4 |
| 2025-01-06 | Myszkowski Kenneth AllenChief Financial Officer | Saleplan | 9,402 | 20.10 | $188,980 | 473,433 | Form 4 |
| 2025-01-06 | O'Brien PatrickCOO and General Counsel | Saleplan | 19,658 | 19.69 | $387,066 | 544,727 | Form 4 |
| 2025-01-06 | O'Brien PatrickCOO and General Counsel | Saleplan | 9,526 | 20.10 | $191,473 | 535,201 | Form 4 |
| 2025-01-06 | Hamilton James CChief Discovery/Trans Medicine | Saleplan | 21,758 | 19.68 | $428,197 | 283,093 | Form 4 |
| 2025-01-06 | Hamilton James CChief Discovery/Trans Medicine | Saleplan | 10,971 | 20.11 | $220,627 | 272,122 | Form 4 |
| 2025-01-02 | Anzalone Christopher RichardDirector, Chief Executive Officer | Saleplan | 11,520 | 19.05 | $219,456 | 3,764,252 | Form 4 |
| 2024-12-27 | Olukotun Adeoye yDirector | Saleplan | 2,850 | 20.00 | $57,000 | 36,740 | Form 4 |
| 2024-12-23 | Anzalone Christopher RichardDirector, Chief Executive Officer | Saleplan | 12,563 | 19.59 | $246,109 | 3,775,772 | Form 4 |
| 2024-12-18 | Anzalone Christopher RichardDirector, Chief Executive Officer | Saleplan | 12,653 | 20.52 | $259,640 | 3,702,394 | Form 4 |
| 2024-12-18 | Anzalone Christopher RichardDirector, Chief Executive Officer | Saleplan | 8,260 | 21.74 | $179,572 | 3,694,134 | Form 4 |
| 2024-12-18 | Anzalone Christopher RichardDirector, Chief Executive Officer | Saleplan | 5,799 | 22.12 | $128,274 | 3,688,335 | Form 4 |
| 2024-12-17 | Given Douglas BDirector | Saleplan | 547 | 22.04 | $12,056 | 124,167 | Form 4 |
| 2024-12-17 | Waddill William D.Director | Saleplan | 3,747 | 22.04 | $82,584 | 40,378 | Form 4 |
| 2024-12-16 | Vakiener VictoriaDirector | Saleplan | 8,994 | 21.91 | $197,059 | 21,211 | Form 4 |
| 2024-12-16 | Given Douglas BDirector | Saleplan | 5,000 | 21.90 | $109,500 | 124,714 | Form 4 |
| 2024-12-16 | Waddill William D.Director | Saleplan | 3,748 | 21.90 | $82,081 | 44,125 | Form 4 |
Grants, exercises and other transactions
Pay, tax and paperwork rather than a choice to trade at the market price. Two years.
25 × grant or award10 × gift4 × option exercise
Show them
| Date | Insider | What | Shares | Price | Holds after | Filing |
|---|---|---|---|---|---|---|
| 2026-06-15 | Cohen Matthew GregoryDirector | Grant or award A | +11,882 | – | 11,882 | Form 4 |
| 2026-01-06 | O'Brien PatrickCOO | Gift G | −540 | – | 474,368 | Form 4 |
| 2026-01-06 | O'Brien PatrickCOO | Gift G | −540 | – | 473,828 | Form 4 |
| 2026-01-06 | O'Brien PatrickCOO | Gift G | −540 | – | 473,288 | Form 4 |
| 2026-01-06 | O'Brien PatrickCOO | Gift G | −440 | – | 472,848 | Form 4 |
| 2026-01-06 | O'Brien PatrickCOO | Gift G | −440 | – | 472,408 | Form 4 |
| 2026-01-06 | O'Brien PatrickCOO | Grant or award A | +75,000 | – | 547,408 | Form 4 |
| 2026-01-06 | Hamilton James CChief Medical Officer | Grant or award A | +75,000 | – | 246,958 | Form 4 |
| 2026-01-06 | Apel Daniel JosephChief Financial Officer | Grant or award A | +75,000 | – | 176,200 | Form 4 |
| 2025-12-31 | O'Brien PatrickCOO | Gift G | −560 | – | 526,641 | Form 4 |
| 2025-12-31 | O'Brien PatrickCOO | Gift G | −560 | – | 526,081 | Form 4 |
| 2025-12-31 | O'Brien PatrickCOO | Gift G | −560 | – | 525,521 | Form 4 |
| 2025-12-31 | O'Brien PatrickCOO | Gift G | −560 | – | 524,961 | Form 4 |
| 2025-12-31 | O'Brien PatrickCOO | Gift G | −560 | – | 524,401 | Form 4 |
| 2025-12-29 | Anzalone Christopher RichardDirector, Chief Executive Officer | Option exercise M | +35,181 | 6.15 | 3,841,107 | Form 4 |
| 2025-12-29 | Anzalone Christopher RichardDirector, Chief Executive Officer | Option exercise M | +16,545 | 6.15 | 3,857,652 | Form 4 |
| 2025-12-16 | Ingram Douglas SDirector | Grant or award A | +7,819 | – | 46,215 | Form 4 |
| 2025-12-16 | Olukotun Adeoye yDirector | Grant or award A | +7,819 | – | 43,600 | Form 4 |
| 2025-12-16 | Perry Michael SDirector | Grant or award A | +7,819 | – | 123,059 | Form 4 |
| 2025-12-16 | Ferrari MauroDirector | Grant or award A | +7,819 | – | 76,583 | Form 4 |
| 2025-12-16 | Waddill William D.Director | Grant or award A | +7,819 | – | 64,930 | Form 4 |
| 2025-12-16 | Lu HongboDirector | Grant or award A | +7,819 | – | 54,982 | Form 4 |
| 2025-12-16 | Vakiener VictoriaDirector | Grant or award A | +7,819 | – | 45,763 | Form 4 |
| 2025-12-12 | Anzalone Christopher RichardDirector, Chief Executive Officer | Grant or award A | +180,000 | – | 4,101,255 | Form 4 |
| 2025-03-13 | Anzalone Christopher RichardDirector, Chief Executive Officer | Grant or award A | +340,000 | – | 4,113,802 | Form 4 |
| 2025-03-04 | Anzalone Christopher RichardDirector, Chief Executive Officer | Option exercise M | +133,333 | 7.75 | 4,073,802 | Form 4 |
| 2025-03-03 | Anzalone Christopher RichardDirector, Chief Executive Officer | Option exercise M | +166,667 | 7.75 | 3,940,469 | Form 4 |
| 2025-02-07 | Anzalone Christopher RichardDirector, Chief Executive Officer | Grant or award A | +9,550 | 20.10 | 3,773,802 | Form 4 |
| 2025-02-06 | Ingram Douglas SDirector | Grant or award A | +38,396 | 20.09 | 38,396 | Form 4 |
| 2025-01-04 | Myszkowski Kenneth AllenChief Financial Officer | Grant or award A | +100,000 | – | 500,600 | Form 4 |
| 2025-01-04 | O'Brien PatrickCOO and General Counsel | Grant or award A | +100,000 | – | 564,385 | Form 4 |
| 2025-01-04 | Hamilton James CChief Discovery/Trans Medicine | Grant or award A | +100,000 | – | 304,851 | Form 4 |
| 2024-12-18 | Anzalone Christopher RichardDirector, Chief Executive Officer | Grant or award A | +100,000 | – | 3,788,335 | Form 4 |
| 2024-12-18 | Lu HongboDirector | Grant or award A | +16,733 | 22.99 | 47,163 | Form 4 |
| 2024-12-18 | Perry Michael SDirector | Grant or award A | +16,733 | 22.99 | 131,490 | Form 4 |
| 2024-12-18 | Ferrari MauroDirector | Grant or award A | +16,733 | 22.99 | 77,514 | Form 4 |
| 2024-12-18 | Waddill William D.Director | Grant or award A | +16,733 | 22.99 | 57,111 | Form 4 |
| 2024-12-18 | Olukotun Adeoye yDirector | Grant or award A | +16,733 | 22.99 | 39,590 | Form 4 |
| 2024-12-18 | Vakiener VictoriaDirector | Grant or award A | +16,733 | 22.99 | 37,944 | Form 4 |
How to read it
- Buy, sale
- Code P and S on the form: shares bought or sold in the market, at the market price. The other codes are mostly pay (a grant, an option exercised) or tax (shares the company withheld), and say little about what the insider thinks of the price.
- Plan
- A sale or purchase under a Rule 10b5-1 plan, set up in advance and running on its own schedule. Since April 2023 the form has a box for it. Much executive selling is planned and says more about diversifying than about the company.
- Holds after
- The shares the insider still held after the trade, in the form the trade was in (directly, or indirectly through a trust or a fund).
- Value
- Shares times the price the form reports, which is often an average over several fills on the day.
Read from the SEC's own quarterly data sets of Forms 3, 4 and 5, and from each day's filings since the last one. A correcting amendment replaces the lines it restates. Every row links to its filing. None of this is advice: insiders sell for many reasons, and buy for fewer.